Results 111 to 120 of about 52,424 (257)

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

Omadacycline: a novel aminomethylcycline

Infection and Drug Resistance, 2019
Rodrigo M Burgos,1 Keith A Rodvold1,21Department of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, Chicago, IL, USA; 2Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, USAAbstract ...
Burgos RM, Rodvold KA
doaj  

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

Management of acute bacterial skin and skin structure infections with a focus on patients at high risk of treatment failure

, 2017
Over the last 25 years, the terminology of skin and soft tissue infections, as well as their classification for optimal management of patients, has changed. The so-called and recently introduced term ‘acute bacterial skin and skin structure infections’ (
Luis Mauricio Hurtado-López, Alejandro Ortiz-Covarrubias, Abel Jalife-Montaño, Abraham Pulido-Cejudo, Mario Guzmán-Gutierrez, Jose Luis Martínez-Ordaz, Héctor Faustino Noyola-Villalobos   +6 more
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Cefdinir: an oral cephalosporin for the treatment of respiratory tract infections and skin and skin structure infections

, 2007
Cefdinir is an oral third-generation cephalosporin (also known as an advanced-spectrum or generation cephem) with good in vitro activity against the pathogens responsible for community-acquired respiratory tract infections and uncomplicated skin and skin
Ronald N Jones, Helio S Sader, Jones, Ronald N., Sader, Helio S. [UNIFESP]   +3 more
core   +1 more source

Multicenter Real-World Outpatient Use of Intravenous Omadacycline

Infectious Diseases and Therapy
Introduction Omadacycline is indicated for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.
Lucinda J. Van Anglen, Cathy L. Koo, Kimberly A. Couch   +2 more
doaj   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

An Assessment of Skin Lesion Measurement Techniques for Use in Clinical Trials of Acute Bacterial Skin and Skin Structure Infections

, 2018
BackgroundLimited data are available to support a reproducible measurement technique that could be used to assess the response of a skin lesion associated with a bacterial infection to antibacterial therapy.MethodsThis multicenter, observational study ...
Michael W. Dunne, Anita Das, George H. Talbot   +2 more
core   +1 more source

Profile of tedizolid phosphate and its potential in the treatment of acute bacterial skin and skin structure infections

Infection and Drug Resistance, 2015
Ronald G Hall 2nd, Heidi N Michaels Texas Tech University Health Sciences Center, Dallas, TX, USA Abstract: Tedizolid phosphate is the first once-daily oxazolidinone approved by the United States Food and Drug Administration for the treatment of acute ...
Hall RG 2nd, Michaels HN
doaj