Antibiotics, 2019 This meta-analysis aims to assess the efficacy and safety of tedizolid, compared to linezolid, in the treatment of acute bacterial skin and skin structure infection (ABSSSI). PubMed, Web of Science, EBSCO (Elton B.
Shao-Huan Lan +6 more
doaj +4 more sources
In vitro activity of tedizolid against 43 species of Nocardia species
Scientific ReportsThe purpose of the present study was to evaluate the in vitro activity of tedizolid against several clinically significant species of Nocardia by comparing with that of linezolid.
Masahiro Toyokawa +9 more
doaj +3 more sources
Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption [PDF]
Clinical and Translational SciencePenetration of antimicrobial treatments into the cerebrospinal fluid is essential to successfully treat infections of the central nervous system. This penetration is hindered by different barriers, including the blood–brain barrier, which is the most ...
Marin Lahouati +5 more
doaj +3 more sources
Prolonged tedizolid use in cutaneous non-tuberculous mycobacterial infection
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2021 Cutaneous non-tuberculous mycobacterial (NTM) infections are an emerging infectious disease and require a protracted course of combination antibiotics. Antimicrobial choice is limited by resistance and toxicity.
Timothy David Shaw +3 more
doaj +2 more sources
Pharmacodynamic evidence for tedizolid use in Mycobacterium avium lung disease [PDF]
IJTLD OpenOBJECTIVE: On guideline-based therapy for Mycobacterium avium complex (MAC) lung disease (LD), ∼50%–60% of patients suffer recalcitrant disease. Tedizolid is a promising agent based on the intracellular hollow fibre model of MAC-LD (HFS-MAC) using the ...
D. Deshpande, S. Srivastava, T. Gumbo
doaj +2 more sources
Pharmacokinetic/Pharmacodynamic Analysis of Tedizolid Phosphate Compared to Linezolid for the Treatment of Infections Caused by Gram-Positive Bacteria [PDF]
Antibiotics, 2021 Tedizolid and linezolid have antibacterial activity against the most important acute bacterial skin and skin-structure infection (ABSSSIs) pathogens.
Alicia Rodríguez-Gascón +3 more
doaj +2 more sources
Current Status and Perspectives of Antibacterial Agents Belonging to 2-Oxazolidinones [PDF]
PharmaceuticalsIn the last three decades, 2-oxazolidinones have emerged as an important class of inhibitors of bacterial protein synthesis, effective in the treatment of multidrug-resistant (MDR) bacterial infections. From a public health perspective, the importance of
Jessica Ceramella +9 more
doaj +2 more sources
LC-MS/MS Method for Simultaneous Quantification of Three Oxazolidinone Antimicrobials in Human Plasma: Application to Therapeutic Drug Monitoring [PDF]
Drug Design, Development and TherapyNa Zhang,* Nan Bai,* Ying Wang, Beibei Liang, Yun Cai Center of Medicine Clinical Research, Department of Pharmacy, Medical Supplies Center, PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors ...
Zhang N, Bai N, Wang Y, Liang B, Cai Y
doaj +2 more sources
Linezolid and tedizolid adverse effects: a review on serotonin syndrome, myelosuppression, neuropathies, and lactic acidosis [PDF]
Antimicrobial Stewardship & Healthcare EpidemiologyOxazolidinone antibiotics—linezolid and tedizolid—are often used to treat multidrug-resistant infections. They are highly bioavailable and ideal for transition to enteral therapy when appropriate.
Adam Greenfield +4 more
doaj +2 more sources
Journal of Pharmaceutical Health Care and Sciences, 2023 Background Tedizolid is an oxazolidinone anti-MRSA drug with included in the National Health Insurance Drug Price List in 2018. The effect of hemodialysis on tedizolid phosphate concentrations has been reported; pre-dialysis concentrations decreased by ...
Satoshi Yoshikawa +3 more
doaj +1 more source