Results 21 to 30 of about 1,804 (172)

The Effectiveness of Linezolid and Teicoplanin for Managing Infections After Burn Injuries: A Retrospective Study. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Gram‐positive infections in burn patients present significant treatment challenges. This study compared the efficacy and safety of linezolid vs. teicoplanin for managing such infections in a clinical setting. Methods We conducted a retrospective study involving 77 burn patients with confirmed Gram‐positive infections at ...
Zendehdel A, Roham M, Soltani S, Jahanshahi A, Heidarizadi S.   +4 more
europepmc   +2 more sources

Tedizolid activity against a multicentre worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae recovered from patients with pneumonia (2017–2019)

International Journal of Infectious Diseases, 2021
Objectives: The antimicrobial activity of tedizolid and comparators was evaluated against a large worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae isolates recovered from patients with pneumonia.
Cecilia G. Carvalhaes, Helio S. Sader, Paul R. Rhomberg, Rodrigo E. Mendes   +3 more
doaj   +1 more source

Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection

Journal of Pharmaceutical Health Care and Sciences, 2023
Background Tedizolid is a new oxazolidinone antibiotic with high potency for the treatment of infections caused by methicillin-resistant Staphylococcus aureus and other species.
Daisuke Negishi, Okimichi Mitsumatsu, Hiromi Mitsumatsu, Miaki Makiguchi, Makiko Shimizu, Hiroshi Yamazaki   +5 more
doaj   +1 more source

Long-Term Use of Tedizolid in Osteoarticular Infections: Benefits among Oxazolidinone Drugs

Antibiotics, 2021
Background: To evaluate the efficacy and safety of long-term use of tedizolid in osteoarticular infections. Methods: Multicentric retrospective study (January 2017–March 2019) of osteoarticular infection cases treated with tedizolid.
Eva Benavent, Laura Morata, Francesc Escrihuela-Vidal, Esteban Alberto Reynaga, Laura Soldevila, Laia Albiach, Maria Luisa Pedro-Botet, Ariadna Padullés, Alex Soriano, Oscar Murillo   +9 more
doaj   +1 more source

In Vitro Activities of Ceftobiprole, Dalbavancin, Tedizolid and Comparators against Clinical Isolates of Methicillin-Resistant Staphylococcus aureus Associated with Skin and Soft Tissue Infections

Antibiotics, 2023
Skin and soft tissue infections (SSTIs) are associated with significant morbidity and healthcare costs, especially when caused by methicillin-resistant Staphylococcus aureus (MRSA).
Sofia Maraki, Viktoria Eirini Mavromanolaki, Dimitra Stafylaki, Evangelia Iliaki-Giannakoudaki, George Hamilos   +4 more
doaj   +1 more source

Tedizolid, Faropenem, and Moxifloxacin Combination With Potential Activity Against Nonreplicating Mycobacterium tuberculosis

Frontiers in Pharmacology, 2021
Background:Mycobacteriumtuberculosis [Mtb] could be present in different metabolic population in the lung lesions, and nonreplicating persisters [NRP], associated with latent tuberculosis [TB], are the most difficult to kill.Objective: Test the ...
Shashikant Srivastava, Shashikant Srivastava, Shashikant Srivastava, Kayle N. Cirrincione, Devyani Deshpande, Tawanda Gumbo, Tawanda Gumbo, Tawanda Gumbo   +7 more
doaj   +1 more source

Tedizolid Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection: A Systematic Review and Meta-Analysis

Antibiotics, 2019
This meta-analysis aims to assess the efficacy and safety of tedizolid, compared to linezolid, in the treatment of acute bacterial skin and skin structure infection (ABSSSI). PubMed, Web of Science, EBSCO (Elton B.
Shao-Huan Lan, Wei-Ting Lin, Shen-Peng Chang, Li-Chin Lu, Chien-Ming Chao, Chih-Cheng Lai, Jui-Hsiang Wang   +6 more
doaj   +1 more source

Synthesis, mechanism of action, and structure-activity relationships of 1,3-oxazolidinones as anti-bacterial Agent: A review [PDF]

المجلة العراقية للصيدلة, 2022
Background: 1,3-oxazolidinones are an important class of antibiotics that are recognized with higher activities against Gram-positive bacteria. linezolid, tedizolid phosphate, and radezolid are important examples of this group.
Ali Hantosh, Nawal Rajab, Faris Abachi
doaj   +1 more source

In vitro activity of Tedizolid and Dalbavancin against MRSA strains is dependent on infection source

International Journal of Infectious Diseases, 2019
Objective: We tested the in vitro susceptibility to Tedizolid and Dalbavancin of Methicillin-resistant Staphylococcus aureus strains recovered from blood and wound cultures, and compared our results with studies conducted in the last four years.
Maya Azrad, Motti Baum, Assaf Rokney, Yish Levi, Avi Peretz   +4 more
doaj   +1 more source

Retrospective Real-World Evaluation of Outcomes in Patients with Skin and Soft Structure Infections Treated with Tedizolid in an Outpatient Setting

Infectious Diseases and Therapy, 2020
Introduction Outcomes data for patients who received tedizolid for acute bacterial skin and skin-structure infections (ABSSSIs) are scant. We provide a real-world analysis of economic and clinical outcomes following tedizolid use in the outpatient ...
Ravina Kullar, Laura A. Puzniak, Jason P. Swindle, Thomas Lodise   +3 more
doaj   +1 more source