Results 21 to 30 of about 546 (157)

Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption

open access: yesClinical and Translational Science
Penetration of antimicrobial treatments into the cerebrospinal fluid is essential to successfully treat infections of the central nervous system. This penetration is hindered by different barriers, including the blood–brain barrier, which is the most ...
Marin Lahouati   +5 more
doaj   +2 more sources

Actividad in vitro del tedizolid y de antibióticos de comparación en aislamientos de Staphylococcus aureus resistentes a meticilina en infecciones de piel y tejidos blandos en siete hospitales de Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2018
Introducción. Staphylococcus aureus resistente a meticilina (SARM) causa infecciones graves de la piel y los tejidos blandos en los hospitales y, en los últimos años, en la comunidad.
Aura Lucía Leal   +9 more
doaj   +3 more sources

Critical role of tedizolid in the treatment of acute bacterial skin and skin structure infections

open access: yesDrug Design, Development and Therapy, 2016
Olivia Ferrández,1,2 Olatz Urbina,1 Santiago Grau1,3 1Hospital Pharmacy, Hospital Universitari del Mar, Barcelona, Spain; 2Nursing Department, Universitat Pompeu Fabra, Barcelona, Spain; 3Medicine Department, Universitat Autònoma de ...
Ferrández O, Urbina O, Grau S
doaj   +1 more source

New developments in the management of severe skin and deep skin structure infections – focus on tedizolid

open access: yesTherapeutics and Clinical Risk Management, 2015
Michael J Durkin,1 G Ralph Corey2,3 1Department of Medicine, Division of Infectious Diseases, Duke University, Durham, NC, USA; 2Department of Medicine, Duke Clinical Research Institute, Durham, NC, USA; 3Duke Global Health Institute, Durham ...
Durkin MJ, Corey GR
doaj   +2 more sources

Tedizolid – a new antibiotic to solve old problems: prospects for the treatment of complicated skin and soft tissue infections

open access: yesАмбулаторная хирургия, 2019
The work describes  a new antibiotic from the oxazolidinone group – tedizolid.  The results  of the clinical studies have shown a high efficacy of tedizolid in complicated  skin and soft tissue infections.
A. V. Rodin, O. I. Agafonov
doaj   +2 more sources

In Vitro Activity of Tedizolid, Dalbavancin, and Ceftobiprole Against Clostridium difficile

open access: yesFrontiers in Microbiology, 2018
Background:Clostridium difficile (C. difficile) is a major nosocomial pathogen that colonizes in the human gut. Recently, the U.S. FDA approved three new antimicrobial agents against gram-positive bacteria: Tedizolid, Dalbavancin, and Ceftobiprole.
Dana Binyamin   +9 more
doaj   +2 more sources

Safety and tolerability of tedizolid as oral treatment for bone and joint infections

open access: yesMicrobiology Spectrum, 2023
Bone and joint infections (BJIs) are common infections increasingly managed with oral therapy. However, there are limited safe oral options for many Gram-positive pathogens.
Loren G. Miller   +10 more
doaj   +1 more source

Tedizolid: new data and experiences for clinical practice [PDF]

open access: yesRevista Española de Quimioterapia, 2021
The most relevant information on the clinical uses of tedizolid from studies published in the last 18 months is presented in this brief review. The most important data indicate better tolerance and safety profile of long-term therapeutic regimes in off-label indications, such as osteoarticular infections and those caused by mycobacteria. Its lower risk
Salavert Lleti, M   +3 more
openaire   +3 more sources

Tedizolid activity against a multicentre worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae recovered from patients with pneumonia (2017–2019)

open access: yesInternational Journal of Infectious Diseases, 2021
Objectives: The antimicrobial activity of tedizolid and comparators was evaluated against a large worldwide collection of Staphylococcus aureus and Streptococcus pneumoniae isolates recovered from patients with pneumonia.
Cecilia G. Carvalhaes   +3 more
doaj   +1 more source

Synovial fluid and plasma concentrations of tedizolid in patients with osteoarthritis infected with Staphylococcus aureus effectively determined with fluorescence detection

open access: yesJournal of Pharmaceutical Health Care and Sciences, 2023
Background Tedizolid is a new oxazolidinone antibiotic with high potency for the treatment of infections caused by methicillin-resistant Staphylococcus aureus and other species.
Daisuke Negishi   +5 more
doaj   +1 more source

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