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Synthesis of Oxazoles Containing CF3-Substituted Alcohol Unit via Tandem Cycloisomerization/Hydroxyalkylation from N-Propargylamides with Trifluoropyruvates [PDF]

open access: yesMolecules
Oxazoles are important five-membered heterocycles that contain both nitrogen and oxygen atoms. Due to their wide range of biological activities, many oxazoles demonstrate potential for extensive application in various fields, including medicinal ...
Juan-Juan Gao   +6 more
doaj   +2 more sources

Synthesis and Optical Properties of N-Arylnaphtho- and Anthra[2,3-d]oxazol-2-amines [PDF]

open access: yesMolecules
Oxazole, a versatile and significant heteroarene, serves as a bridge between synthetic organic chemistry and applications in the medicinal, pharmaceutical, and industrial fields.
Yuki Murata   +4 more
doaj   +2 more sources

GO/MNPs–TEA–CuI in water: a green and efficient catalytic system for multicomponent preparation of highly substituted imidazoles and oxazoles [PDF]

open access: yesFrontiers in Chemistry
A sustainable and highly efficient catalytic protocol has been developed employing graphene oxide-supported magnetic nanoparticles functionalized with triethanolamine and copper(I) iodide (GO/MNPs–TEA–CuI) for the synthesis of functionalized imidazole ...
Mohamed Abu Shuheil   +7 more
doaj   +2 more sources

Divergent photochemical ring-replacement of isoxazoles [PDF]

open access: yesNature Communications
Isoxazoles, oxazoles, and other five-membered heteroaromatics are prevalent motifs in core structure of pharmaceuticals and agrochemicals. In early-stage drug discovery, it is common practice to prepare libraries of analogues featuring different ...
Yan Xu   +5 more
doaj   +2 more sources

Benzo[d]oxazoles from Anilides by N-Deprotonation–O-SNAr Cyclization [PDF]

open access: yesMolecules
A synthesis of benzo[d]oxazoles by an N-deprotonation–O-SNAr cyclization sequence from anilide precursors is reported. Anilides derived from 2-fluorobenzaldehydes, activated toward SNAr ring closure by C5 electron-withdrawing groups, were prepared and ...
Nash E. Nevels   +2 more
doaj   +2 more sources

Development and application of in silico models to design new antibacterial 5-amino-4-cyano-1,3-oxazoles against colistin-resistant E. coli strains

open access: yesArtificial Intelligence Chemistry, 2023
Here we describe the results of QSAR analysis based on artificial neural networks, synthesis, activity evaluation and molecular docking of a number of 1,3-oxazole derivatives as anti-E. coli antibacterials.
Ivan Semenyuta   +7 more
doaj   +1 more source

Suzuki Coupling of Oxazoles [PDF]

open access: yesOrganic Letters, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Flegeau, Emmanuel Ferrer   +2 more
openaire   +3 more sources

Synthesis and Characterization of Novel Heterocyclic Chalcones from 1-Phenyl-1H-pyrazol-3-ol

open access: yesMolecules, 2022
An efficient synthetic route to construct diverse pyrazole-based chalcones from 1-phenyl-1H-pyrazol-3-ols bearing a formyl or acetyl group on the C4 position of pyrazole ring, employing a base-catalysed Claisen–Schmidt condensation reaction, is described.
Arminas Urbonavičius   +9 more
doaj   +1 more source

Core spectroscopy of oxazole

open access: yesThe Journal of Chemical Physics, 2022
We have measured, analyzed, and simulated the ground state valence photoelectron spectrum, x-ray absorption (XA) spectrum, x-ray photoelectron (XP) spectrum as well as normal and resonant Auger–Meitner electron (AE) spectrum of oxazole at the carbon, oxygen, and nitrogen K-edge in order to understand its electronic structure.
Anna Kristina Schnack-Petersen   +8 more
openaire   +3 more sources

Weak Intermolecular Interactions in a Series of Bioactive Oxazoles

open access: yesMolecules, 2021
The intermolecular interactions in a series of nine similar 4,5-phenyl-oxazoles were studied on the basis of crystal structures determined by X-ray diffraction. The crystal architectures were analyzed for the importance and hierarchies of different, weak
Anita M. Grześkiewicz   +2 more
doaj   +1 more source

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