Synthesis of Oxazoles Containing CF3-Substituted Alcohol Unit via Tandem Cycloisomerization/Hydroxyalkylation from N-Propargylamides with Trifluoropyruvates [PDF]
MoleculesOxazoles are important five-membered heterocycles that contain both nitrogen and oxygen atoms. Due to their wide range of biological activities, many oxazoles demonstrate potential for extensive application in various fields, including medicinal ...
Juan-Juan Gao +6 more
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Synthesis and Optical Properties of N-Arylnaphtho- and Anthra[2,3-d]oxazol-2-amines [PDF]
MoleculesOxazole, a versatile and significant heteroarene, serves as a bridge between synthetic organic chemistry and applications in the medicinal, pharmaceutical, and industrial fields.
Yuki Murata +4 more
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GO/MNPs–TEA–CuI in water: a green and efficient catalytic system for multicomponent preparation of highly substituted imidazoles and oxazoles [PDF]
Frontiers in ChemistryA sustainable and highly efficient catalytic protocol has been developed employing graphene oxide-supported magnetic nanoparticles functionalized with triethanolamine and copper(I) iodide (GO/MNPs–TEA–CuI) for the synthesis of functionalized imidazole ...
Mohamed Abu Shuheil +7 more
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Divergent photochemical ring-replacement of isoxazoles [PDF]
Nature CommunicationsIsoxazoles, oxazoles, and other five-membered heteroaromatics are prevalent motifs in core structure of pharmaceuticals and agrochemicals. In early-stage drug discovery, it is common practice to prepare libraries of analogues featuring different ...
Yan Xu +5 more
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Benzo[d]oxazoles from Anilides by N-Deprotonation–O-SNAr Cyclization [PDF]
MoleculesA synthesis of benzo[d]oxazoles by an N-deprotonation–O-SNAr cyclization sequence from anilide precursors is reported. Anilides derived from 2-fluorobenzaldehydes, activated toward SNAr ring closure by C5 electron-withdrawing groups, were prepared and ...
Nash E. Nevels +2 more
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Artificial Intelligence Chemistry, 2023 Here we describe the results of QSAR analysis based on artificial neural networks, synthesis, activity evaluation and molecular docking of a number of 1,3-oxazole derivatives as anti-E. coli antibacterials.
Ivan Semenyuta +7 more
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Synthesis and Characterization of Novel Heterocyclic Chalcones from 1-Phenyl-1H-pyrazol-3-ol
Molecules, 2022 An efficient synthetic route to construct diverse pyrazole-based chalcones from 1-phenyl-1H-pyrazol-3-ols bearing a formyl or acetyl group on the C4 position of pyrazole ring, employing a base-catalysed Claisen–Schmidt condensation reaction, is described.
Arminas Urbonavičius +9 more
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Suzuki Coupling of Oxazoles [PDF]
Organic Letters, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Flegeau, Emmanuel Ferrer +2 more
openaire +3 more sources
Weak Intermolecular Interactions in a Series of Bioactive Oxazoles
Molecules, 2021 The intermolecular interactions in a series of nine similar 4,5-phenyl-oxazoles were studied on the basis of crystal structures determined by X-ray diffraction. The crystal architectures were analyzed for the importance and hierarchies of different, weak
Anita M. Grześkiewicz +2 more
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Isomerization of 5-(2H-Azirin-2-yl)oxazoles: An Atom-Economic Approach to 4H-Pyrrolo[2,3-d]oxazoles
Molecules, 2021 An atom economical method for the preparation of variously substituted 4H-pyrrolo[2,3-d]oxazoles was developed on the basis of thermal isomerization of 5-(2H-azirin-2-yl)oxazoles.
Timur O. Zanakhov +4 more
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