Results 21 to 30 of about 3,191 (185)

Diazocarbonyl and Related Compounds in the Synthesis of Azoles

Molecules, 2021
Diazocarbonyl compounds have found numerous applications in many areas of chemistry. Among the most developed fields of diazo chemistry is the preparation of azoles from diazo compounds.
Anton Budeev, Grigory Kantin, Dmitry Dar’in, Mikhail Krasavin   +3 more
doaj   +1 more source

Gold Catalyzed Multicomponent Reactions beyond A3 Coupling

Molecules, 2018
The preparation of complex architectures has inspired the search for new methods and new processes in organic synthesis. Multicomponent reactions have become an interesting approach to achieve such molecular diversity and complexity.
Renso Visbal, Sara Graus, Raquel P. Herrera, M. Concepción Gimeno   +3 more
doaj   +1 more source

Simple and Expedient Access to Novel Fluorinated Thiazolo- and Oxazolo[3,2-a]pyrimidin-7-one Derivatives and Their Functionalization via Palladium-Catalyzed Reactions

Molecules, 2022
An efficient, versatile, and one-pot method for the preparation of novel fluorinated thiazolo- and oxazolo[3,2-a]pyrimidin-7-ones is described from 2-aminothiazoles or 2-amino-oxazoles and fluorinated alkynoates.
Wafa Blancou, Badr Jismy, Soufiane Touil, Hassan Allouchi, Mohamed Abarbri   +4 more
doaj   +1 more source

1,4- Addition of diazomethane to a heterodiene: a direct preparation of the oxazolic ring

Anais da Academia Brasileira de Ciências, 2007
The reaction of naphthoquinone-oximes (3) and (4) with diazomethane yields directly, in one step, the oxazoles (5) and (6), respectively.A reação das naphthoquinona-oximas (3) e (4) com diazometano fornece diretamente, em uma etapa, os oxazóis (5) e (6),
Flávio da S. Emery, Raphael S.F. Silva, Kelly C.G. de Moura, Maria C.F.R. Pinto, Mauro B. Amorim, Valéria R.S. Malta, Regina H.A. Santos, Kátia M. Honório, Albérico B.F. da Silva, Antonio V. Pinto   +9 more
doaj   +1 more source

2-(3-Bromophenyl)imidazo[2,1-b]oxazole

Molbank, 2023
The microwave-assisted reaction of 2-nitroimidazole with 3-bromophenacyl bromide in the presence of potassium carbonate as a base and dimethylformamide as a solvent afforded 2-(3-bromophenyl)imidazo[2,1-b]oxazole.
Ángel Cores, Mercedes Villacampa, J. Carlos Menéndez   +2 more
doaj   +1 more source

Identification and isolation of insecticidal oxazoles from Pseudomonas spp.

Beilstein Journal of Organic Chemistry, 2012
Two new and five known oxazoles were identified from two different Pseudomonas strains in addition to the known pyrones pseudopyronine A and B. Labeling experiments confirmed their structures and gave initial evidence for a novel biosynthesis pathway of ...
Florian Grundmann, Veronika Dill, Andrea Dowling, Aunchalee Thanwisai, Edna Bode, Narisara Chantratita, Richard ffrench-Constant, Helge B. Bode   +7 more
doaj   +1 more source

Investigation on the reactivity of α-azidochalcones with carboxylic acids: Formation of α-amido-1,3-diketones and highly substituted 2-(trifluoromethyl)oxazoles

Beilstein Journal of Organic Chemistry, 2015
The reaction of α-azidochalcones with carboxylic acids has been investigated resulting in the formation of α-amido-1,3-diketones under microwave irradiation via in situ formation of 2H-azirine intermediates.
Kandasamy Rajaguru, Arumugam Mariappan, Rajendran Suresh, Periasamy Manivannan, Shanmugam Muthusubramanian   +4 more
doaj   +1 more source

The LANCA three-component reaction to highly substituted β-ketoenamides – versatile intermediates for the synthesis of functionalized pyridine, pyrimidine, oxazole and quinoxaline derivatives

Beilstein Journal of Organic Chemistry, 2019
The LANCA three-component reaction of lithiated alkoxyallenes LA, nitriles N and carboxylic acids CA leads to β-ketoenamides KE in good to excellent yields.
Tilman Lechel, Roopender Kumar, Mrinal K. Bera, Reinhold Zimmer, Hans-Ulrich Reissig   +4 more
doaj   +1 more source

Recent Advances on O-Ethoxycarbonyl and O-Acyl Protected Cyanohydrins

Molecules, 2021
Ethoxycarbonyl cyanohydrins and O-acyl cyanohydrins are examples of O-protected cyanohydrins in which the protecting group presents an electrophilic center, contributing to additional reaction pathways.
Héctor Manuel Torres Domínguez, Luis Mauricio Hernández Villaverde, Ronan Le Lagadec   +2 more
doaj   +1 more source

Unified Synthesis of Unconventional α‐Polyhalogenated Amines Through Hydroaminoalkylation

Angewandte Chemie International Edition, EarlyView.
A unified, redox‐neutral method that transforms alkenes and alkynes into α‐polyhalomethyl amines using stable hemiaminal reagents is reported. This approach enables access to CF3, CF2H, CF2Cl, and CFClH motifs, expanding halogenated amine space with broad substrate scope, functional group tolerance, and applicability to late‐stage modification of drug ...
Angela K. Hofmeister, Giulia Iannelli, Péter Angyal, Augustin Malandain, Daniel Kaiser, Boris Maryasin, Hanspeter Kählig, Matteo Barel, Gaia Novarino, Nuno Maulide   +9 more
wiley   +1 more source