Results 1 to 10 of about 9,110 (223)

Azole γ‐Peptides Helix Switching via Heterocycle Substitutions [PDF]

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
Heterocycle substitution in azole‐based γ‐amino acids enables control over the helical shape of heterocyclic γ‐peptides. S↔N permutation in thiazole residues switches a canonical 9‐helix into a flexible helix exhibiting discontinuous hydrogen bonding.
Samantha Chaise, Claude Didierjean, Audrey Gacogne, Maxime Fillaudeau, Young Kee Kang, Aurélien Lebrun, Jean‐Louis Bantignies, Dominique Housset, Muriel Amblard, Ludovic T. Maillard, Baptiste Legrand   +10 more
wiley   +3 more sources

A High-Efficiency Deep Blue Emitter for OLEDs with a New Dual-Core Structure Incorporating ETL Characteristics

Molecules, 2023
In this study, we introduced the weak electron-accepting oxazole derivative 4,5-diphenyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxazole (TPO) into both anthracene and pyrene moieties of a dual core structure. Ultimately, we developed 2-(
Yeongjae Heo, Hyukmin Kwon, Sangwook Park, Sunwoo Dae, Hayoon Lee, Kiho Lee, Jongwook Park   +6 more
doaj   +1 more source

Crystal structure and Hirshfeld-surface analysis of the pesticide etoxazole

Acta Crystallographica Section E: Crystallographic Communications
Etoxazole (C21H23F2NO2), systematic name 4-(4-tert-butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazole, is a fluorinated insecticide and acaricide that inhibits chitin biosynthesis, disrupting insect development by preventing proper ...
Chaluvarangaiah Sowbhagya, Thaluru M. Mohan Kumar, Hemmige S. Yathirajan, Sean Parkin   +3 more
doaj   +1 more source

Design, synthesis and biological evaluation of 3-(2-aminooxazol-5-yl)-2H-chromen-2-one derivatives

Chemistry Central Journal, 2018
Background In view of wide range of biological activities of oxazole, a new series of oxazole analogues was synthesized and its chemical structures were confirmed by spectral data (Proton/Carbon-NMR, IR, MS etc.). The synthesized oxazole derivatives were
Saloni Kakkar, Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah, Balasubramanian Narasimhan   +6 more
doaj   +1 more source

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

Angewandte Chemie International Edition, EarlyView.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee‐Ann J. Keane, Patrick McArdle, Nicholas D. J. Yates, Christopher D. Spicer, Alison Parkin, Martin A. Fascione, Eddie L. Myers   +9 more
wiley   +1 more source

Recent advances in direct C–H arylation: Methodology, selectivity and mechanism in oxazole series

Beilstein Journal of Organic Chemistry, 2011
Catalytic direct (hetero)arylation of (hetero)arenes is an attractive alternative to traditional Kumada, Stille, Negishi and Suzuki–Miyaura cross-coupling reactions, notably as it avoids the prior preparation and isolation of (hetero)arylmetals ...
Cécile Verrier, Pierrik Lassalas, Laure Théveau, Guy Quéguiner, François Trécourt, Francis Marsais, Christophe Hoarau   +6 more
doaj   +1 more source

Poly[3-methyl-1,3-oxazolidin-2-iminium[µ₃-cyanido-tri-µ₂-cyanido-κ⁹C:N-tricuprate(I)]]

Molbank, 2021
The unexpected formation of an oxazole ring has occurred during synthesis of a copper(I) cyanide network polymer as part of our ongoing studies of the structural chemistry of these networks. Crystals of the title compound were formed during the synthesis
Leena N. Rachid, Peter W. R. Corfield
doaj   +1 more source

Development and validation of the method of quantification of 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide and its metabolites in laboratory animal plasma

Разработка и регистрация лекарственных средств
Introduction. The study of the systemic exposure of a new original drug is an essential part of its preclinical study. 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide is a new selective carbonic anhydrase II inhibitor for the treatment of ...
I. I. Yaichkov, M. K. Korsakov, A. A. Shetnev, N. N. Volkhin, S. S. Petukhov   +4 more
doaj   +1 more source

Density Functional Theory Applied to Excited State Intramolecular Proton Transfer in Imidazole-, Oxazole-, and Thiazole-Based Systems

Molecules, 2018
Excited state intramolecular proton transfer (ESIPT) is a photoinduced process strongly associated to hydrogen bonding within a molecular framework. In this manuscript, we computed potential energy data using Time Dependent Density Functional Theory ...
Fabricio de Carvalho, Maurício D. Coutinho Neto, Fernando H. Bartoloni, Paula Homem-de-Mello   +3 more
doaj   +1 more source

Cyclization of Activated Methylene Isocyanides with Methyl N(N),N′-Di(tri)substituted Carbamimidothioate: A Novel Entry for the Synthesis of N,1-Aryl-4-tosyl/ethoxycarbonyl-1H-imidazol-5-amines

SynOpen, 2019
Base-induced cyclization of active methylene isocyanides with carbamimidothioates for the synthesis of N,1-aryl-4-tosyl/ethylcarboxy-1H-imidazol-5-amines is reported.
Dukanya Dukanya, Toreshettahally R. Swaroop, Shobith Rangappa, Kanchugarakoppal S. Rangappa, Basappa Basappa   +4 more
doaj   +1 more source