Results 1 to 10 of about 35,784 (226)
Synthesis, Characterization, and DFT of Some Thiazole Derivatives as Carbon Steel Corrosion Inhibitors in 1 M HCl. [PDF]
Chem BiodiversBy reacting 2‐(1‐(4‐aminophenyl)ethylidene)hydrazine‐1‐carbothioamide (1) with various α‐halocarbonyl compounds, such as 3‐chloropentane‐2,4‐dione 2 and 1‐chloro‐1‐((4‐substituted phenyl)diazenyl)propan‐2‐one 4a–c, this work produces a new series of thiazole derivatives 3 and 5a–c.
Mahmoud AO +4 more
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Pyridyl-Thiazole-Thiosemicarbazones as Antitrypanosomatidae Agents: Design, Synthesis, and In Silico Profiling. [PDF]
ChemMedChemA novel pyridine–thiazole derivative, Compound 8, exhibited potent dual antitrypanosomatid activity. It demonstrated remarkable in vitro efficacy against Trypanosoma cruzi (IC50 = 1.0 µM) and L. amazonensis (IC50 = 3.9 µM). Molecular docking studies suggested interactions with heme and multiple molecular targets.
Silva AJFSD +10 more
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Biosynthesis of the Thiamin-Thiazole in Eukaryotes: Identification of a Thiazole Tautomer Intermediate [PDF]
Journal of the American Chemical Society, 2008 Thiamin thiazole biosynthesis in eukaryotes is still not completely understood. In this report, a late intermediate, tightly bound to the active site of the Saccharomyces cerevisiae thiazole synthase, was identified as an adenylated thiazole tautomer. The reactivity of this unusual compound was evaluated.
Abhishek, Chatterjee +4 more
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Thiazoles in Peptides and Peptidomimetics [PDF]
, 2015 The natural occurrence of the thiazole ring in chemistry and biology has inspired its widespread use in synthetic peptidomimetics as structural templates, biological probes, and pharmaceuticals. Thiazole can be viewed as a dehydrated cyclized derivative of cysteine, incorporated into peptide sequences through chemical synthesis or ribosomal ...
Mak, Jeffrey Y. W. +2 more
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Thiazoles in glycosylation reactions: Novel synthesis of thiazole thioglycosides
Heteroatom Chemistry, 2017 AbstractThis research reports a novel method for synthesizing new thiazole thioglycosides. This series of thiazole thioglycosides were designed by the reaction of potassium cyanocarbonimidodithioate 2 with benzoyl acetonitrile 3a and ethyl bromoacetate 3b in the presence of ethanol‐KOH to give the corresponding potassium 4‐amino‐5‐substituted‐thiazole ...
Mamdouh A. Abu‐Zaied +1 more
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Bioactive thiazole and benzothiazole derivatives
European Journal of Medicinal Chemistry, 2015 The heterocycles are the versatile compounds existing in almost all natural products and synthetic organic compounds, usually associated with one or the other biological activity. Among the heterocycles the thiazoles and benzothiazoles occupy a prominent position.
Rouf, Abdul, Tanyeli, Cihangir
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Thermodynamic Functions of Thiazole and iso-Thiazole
Croatica Chemica Acta, 1968 Some thermodynamic functions (the enthalpy and free energy functi ons, entropy and heat capacity) of thiazole and iso-thiazole have been calculated (300-1000° K), using the harmonic-oscillator, rigid-rotor approximation. The reported assignments for the two molecules were us ed, as were the published values for the moments of inertia of thiazole ...
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Thiazole Effect on Phycomyces [PDF]
Proceedings of the National Academy of Sciences, 1941 W J, Robbins, F, Kavanagh
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Recent advances in thiazole-based derivatives targeting diverse anti-inflammatory pathways. [PDF]
RSC AdvDawood DH +4 more
europepmc +1 more source