Results 41 to 50 of about 36,963 (239)

Thiazoles in Peptides and Peptidomimetics [PDF]

, 2015
The natural occurrence of the thiazole ring in chemistry and biology has inspired its widespread use in synthetic peptidomimetics as structural templates, biological probes, and pharmaceuticals. Thiazole can be viewed as a dehydrated cyclized derivative of cysteine, incorporated into peptide sequences through chemical synthesis or ribosomal ...
Mak, Jeffrey Y. W., Xu, Weijun, Fairlie, David P.   +2 more
openaire   +3 more sources

Chalcogen‐Bond‐Driven Electrochemical Bromide Sequestration in Benzothiazole‐Functionalized Covalent Organic Frameworks

Angewandte Chemie, EarlyView.
To address the unresolved challenge of selective bromide removal from reverse‐osmosis permeate, we developed benzothiazole‐functionalized COF/rGO electrodes that exploit directional chalcogen bonding to preferentially capture Br− over Cl−. The mesoporous BTzTp@rGO electrode achieved a maximum Br− uptake of 36.7 mg g−1, a Br−/Cl− selectivity factor of ...
Najat Maher Aldaqqa, Rajesh Dhanushkotti, Sara Vaca‐Chacon, Sushil Kumar, Thibault Terencio, Kyriaki Polychronopoulou, Gisha Elizabeth Luckachan, Dinesh Shetty   +7 more
wiley   +2 more sources

Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms

Molecules, 2021
Coumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules ...
Eslam Reda El-Sawy, Ahmed Bakr Abdelwahab, Gilbert Kirsch   +2 more
doaj   +1 more source

Thiazole-Induced Quinoid Polymers for Efficient Solar Cells: Influence of Molecular Skeleton, Regioselectivity, and Regioregularity

, 2018
Fluorination strategy has been regarded as a promising approach to improve the photovoltaic performance in polymer solar cells. However, the synthesis is relatively tedious and costly for most fluorinated momomers.
Bilal Shahid (4427476), Yonghai Li (1933006), Dangqiang Zhu (1615996), Renqiang Yang, Meng Qiu (406483), Renqiang Yang (554437), Yingying Wang (124944), Yonghai Li, Xichang Bao, Meng Qiu, Qian Wang (32718), Bilal Shahid, Xichang Bao (1504375), Yingying Wang, Qian Wang, Dangqiang Zhu   +15 more
core   +1 more source

Effect of novel 2-amino-5-benzylthiazole derivative on cellular ultrastructure and activity of antioxidant system in murine lymphoma cells

Біологічні студії, 2019
The influence of newly synthesized thiazole derivative N-(5-benzyl-1,3-thiazol-2-yl)-3,5-dimethyl-1-benzofuran-2-carboxamide on cellular ultrastructure and anti­oxidant system activity in lymphoma cells was studied in vitro. A pronounced cytotoxic action
Ya. R. Shalai, M. V. Popovych, O. R. Kulachkovskyy, V. P. Hreniukh, S. M. Mandzynets, N. S. Finiuk, A. M. Babsky   +6 more
doaj   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Riluzole‐Derived Benzo[d]thiazoles as CK1δ Inhibitors for Amyotrophic Lateral Sclerosis‐Related Neurodegeneration [PDF]

ChemMedChem
Riluzole metabolism guided the design of benzo[d]thiazole inhibitors of casein kinase 1 delta (CK1δ), a kinase linked to amyotrophic lateral sclerosis (ALS). Docking supported ATP site recognition by the hydroxylamine metabolite and hydrazine analogues, leading to compounds showing improved potency and retained predicted blood brain barrier ...
Adorinni S, Grieco I, Morasso S, Fornasier M, Novello G, Salmaso V, Martínez‐González L, Cescon E, Bassani D, Bassan G, Gianferrara T, Prencipe F, Kost V, Da Ros T, Storici P, Martinez A, Spalluto G, Moro S, Federico S.   +18 more
europepmc   +2 more sources

Core and π‐Bridge Engineering to Deconstruct Y6‐Series into Modular Non‐Fused Acceptors: DFT‐Guided Structure‐Property Map for Organic Solar Cells

Advanced Electronic Materials, EarlyView.
The rigid fused backbone of Y6‐series acceptors is deconstructed into a modular, non‐fused A‐π‐A′‐π‐A architecture. Comprehensive quantum chemical simulations reveal that strategic core and π‐bridge engineering preserves strong near‐infrared light‐harvesting and enhances intramolecular charge‐transfer character.
Qurat ul Ain, Waqas Akram, Hasan Yaqoob, Munazza Shahid, Abdul Majid, Muhammad Altaf, Christian B. Nielsen, Raja Shahid Ashraf   +7 more
wiley   +1 more source

Short Review on Thiazole Derivative [PDF]

, 2019
Thiazole is aromatic, heterocyclic organic compound that have five membered molecular ring structures C3H3NS. Thiazole was first described by Hantzch and Weber in 1887. Prop confirmed its structure in 1889.
Pradhan, Alka, Qureshi, Abida
core   +1 more source

Generative and Experimental Validation of High Refractive Index Polymers via Domain Knowledge Approach with Small Data

Advanced Intelligent Discovery, EarlyView.
This research demonstrates that the combination of domain knowledge–based multiple regression, multi‐objective Bayesian optimization, and generative models is a suitable prediction tool for candidates of high refractive index polymers, even with the constraints in the model trained on limited data. The experimental validation can reproduce the proposed
Takuya Yokoo, Seigo Watanabe, Hana Matsunaga, Kenichi Oyaizu   +3 more
wiley   +1 more source