Results 61 to 70 of about 46,327 (259)

Novel Thiazole Derivatives Containing Imidazole and Furan Scaffold: Design, Synthesis, Molecular Docking, Antibacterial, and Antioxidant Evaluation

Molecules
Carbothioamides 3a,b were generated in high yield by reacting furan imidazolyl ketone 1 with N-arylthiosemicarbazide in EtOH with a catalytic amount of conc. HCl.
F. Agili
semanticscholar   +1 more source

Generative and Experimental Validation of High Refractive Index Polymers via Domain Knowledge Approach with Small Data

Advanced Intelligent Discovery, EarlyView.
This research demonstrates that the combination of domain knowledge–based multiple regression, multi‐objective Bayesian optimization, and generative models is a suitable prediction tool for candidates of high refractive index polymers, even with the constraints in the model trained on limited data. The experimental validation can reproduce the proposed
Takuya Yokoo, Seigo Watanabe, Hana Matsunaga, Kenichi Oyaizu   +3 more
wiley   +1 more source

Effect of Thiazole Derivatives on Copper Corrosion in Acidic Sulphate Solution

International Journal of Electrochemical Science, 2015
Inhibition of copper corrosion in 0.1 mol dm-3 Na2SO4 solution (pH 3) by two thiazole derivatives of 5-(5'-methylfurfurylidene-2')-2,4-dioxotetrahydro-1,3-thiazole (MFDT) and 2-thiono-5-(4'-ethoxybenzylidene)-4-oxotetrahydro-1,3-thiazole (TEBOT) was ...
Jelena Nakomčić, Gyöngyi Vastag, Abdul Shaban, Lajos Nyikos   +3 more
doaj   +1 more source

Nucleic Acid Specificity, Cellular Localization and Reduced Toxicities of Thiazole Orange‐Neomycin Conjugates

ChemistryOpen
Selective binding of small molecule ligands to nucleic acids with high affinity and limited toxicity remains an important goal in the development of compounds that can probe DNA or RNA in cells.
Antwine W. McFarland Jr., Lawrence P. Fernando, Patrick Kellish, Sandra P. Story, Gretchen B. Schober, Sunil Kumar, Changjun Gong, Ada King, Xianchang Gong, Alain S. Leutou, Dev P. Arya   +10 more
doaj   +1 more source

Overview on Biological Activities of Thiazole Derivatives [PDF]

Records of Pharmaceutical & Biomedical Sciences
Thiazole and its derivatives have garnered widespread attention in medicinal chemistry due to their remarkable range of biological activities. This heterocyclic scaffold is characterized by a five-membered aromatic ring that incorporates both nitrogen ...
Omnia Beker, Marwa Elewa, Yasser Loksha, Hossam Elshihawy   +3 more
doaj   +1 more source

Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation

Molecules, 2021
Compounds bearing thiazole and chalcone pharmacophores have been reported to possess excellent antitubercular and anticancer activities. In view of this, we designed, synthesized and characterized a novel series of thiazole–chalcone hybrids (1–20) and ...
Ashok Babu Kasetti, I. Singhvi, Ravindra Nagasuri, Richie R. Bhandare, A. Shaik   +4 more
semanticscholar   +1 more source

The newly synthesized thiazole derivatives as potential antifungal compounds against Candida albicans

Applied Microbiology and Biotechnology, 2021
Recently, the occurrence of candidiasis has increased dramatically, especially in immunocompromised patients. Additionally, their treatment is often ineffective due to the resistance of yeasts to antimycotics. Therefore, there is a need to search for new
Anna Biernasiuk, Anna Berecka-Rycerz, A. Gumieniczek, Maria Malm, Krzysztof Z. Łączkowski, J. Szymańska, A. Malm   +6 more
semanticscholar   +1 more source

6-Bromo-2-methylsulfanyl-1,3-benzothiazole

Acta Crystallographica Section E, 2011
The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS ...
Michał A. Dobrowolski, Marta Struga, Daniel Szulczyk   +2 more
doaj   +1 more source

1,3-Thiazole-4-carbonitrile

IUCrData, 2021
The title compound, C4H2N2S, is a 1,3-thiazole substituted in the 4-position by a nitrile group. In the crystal, C—H...N hydrogen bonds and aromatic π–π stacking interactions are observed.
Martin J. G. Fait, Anke Spannenberg, Evgenii V. Kondratenko, David Linke   +3 more
doaj   +1 more source

SYNTHESIS OF SOME NEW 2,4,6-TRISUBSTITUTEDTHIAZOLO-[5,4-d] PYRIMIDINE-5,7(4H,6H)-DIONES.

Zagazig Journal of Pharmaceutical Sciences, 1999
Reaction of 2,6-disubstitutedthiazolo5,4-dpyrimidin-7(6H)-ones 2 with ethyl chloroformate/ethanol mixture afforded 5-(ethoxycarbonylamino) -2-(substitutedthio) thiazole-4-(N-substituted)-carboxamides 4a-c.
Wahid Basyouni , Hanaa Hosni
doaj   +1 more source