Results 61 to 70 of about 36,963 (239)

Die Aza‐Büchner–Curtius–Schlotterbeck‐Reaktion: Selektive Bildung Quartärer Kohlenstoffzentren

Angewandte Chemie, EarlyView.
Wir stellen die Aza‐Büchner–Curtius–Schlotterbeck‐(ABCS)‐Reaktion vor: eine milde, katalysatorfreie Methode zur Homologierung von Aryliminen. Im Gegensatz zum traditionellen BCS‐Mechanismus durchläuft das Diazo‐Intermediat eine selektive C─C‐Insertion zur Bildung eines quartären Zentrums.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

1,3-Thiazole-4-carbonitrile

IUCrData, 2021
The title compound, C4H2N2S, is a 1,3-thiazole substituted in the 4-position by a nitrile group. In the crystal, C—H...N hydrogen bonds and aromatic π–π stacking interactions are observed.
Martin J. G. Fait, Anke Spannenberg, Evgenii V. Kondratenko, David Linke   +3 more
doaj   +1 more source

A comprehensive review on thiazole derivatives as multifunctional therapeutics

Discover Chemistry
Thiazole, a versatile five-membered heterocyclic scaffold containing sulfur and nitrogen atoms, has emerged as a pivotal pharmacophore in medicinal chemistry due to its unique chemical properties and broad spectrum of biological activities.
Dattatray N. Thorat, Krutika S. Sonar, Sandip R. Kale, Anoop Singh, Sandip D. Patil, Pramodkumar Awasthi   +5 more
doaj   +1 more source

4-[Bis(thiazol-2-ylamino)methyl]phenol

Molbank, 2023
We have designed and synthesized novel bis-thiazole derivative. A 4-[bis(thiazol-2-ylamino)methyl]phenol was efficiently prepared in 71% yield by the reaction of 2-aminothiazole with 4-hydroxybenzaldehyde in ethanol for 24 h.
Joanna Cytarska, Anna Kolasa
doaj   +1 more source

Ranking ligand affinity for the DNA minor groove by experiment and simulation [PDF]

, 2010
The structural and thermodynamic basis for the strength and selectivity of the interactions of minor-groove binders (MGBs) with DNA is not fully understood.
Wittayanarakul, Kitiyaporn, Parkinson, John A, Hannongbua, Supa, Anthony, Nahoum G., Treesuwan, Witcha, Suckling, Colin J., Khalaf, Abedawn I., Alniss, Hasan, Mackay, Simon P.   +8 more
core   +3 more sources

CORROSION INHIBITION PERFOMANCE OF FOUR NATURAL THIAZOLE DERIVATIVES: QUANTUM CHEMICAL AND MONTE CARLO SIMULATION STUDIE [PDF]

, 2018
Some thiazole derivatives: 2-acetyl-thiazole, 2-isobutyl-thiazole, 4-methyl-5-(2-hydroxyethyl)-thiazole, 2,4,5-trimethyl-thiazole used as corrosion inhibitors for iron were calculated at DFT-PBEPBE/6-31+G(d,p) level of theory and by Monte Carlo ...
Duy Quang Dao
core   +2 more sources

Crystal structure and Hirshfeld surface analysis of 4-(naphthalen-2-yl)-N-[(Z)-4-propoxybenzylidene]-1,3-thiazol-2-amine

Acta Crystallographica Section E: Crystallographic Communications, 2020
The asymmetric unit of the title compound, C23H20N2OS, contains one slightly bent molecule. The naphthalene ring system and the thiazole ring are twisted with respect to each other, making a dihedral angle of 13.69 (10)°; the anisole ring is inclined to ...
Ropak A. Sheakh Mohamad, Wali M. Hamad, Hashim J. Aziz   +2 more
doaj   +1 more source

Strain-Based Design, Direct Macrocyclization, and Metal Complexation of Thiazole-Containing Calix[3]pyrrole Analogues [PDF]

Coordination chemistry of ring-contracted porphyrins, such as subporphyrin and calix[3]pyrrole, has been largely unexplored due to the synthetic difficulty of their free-base analogues.
Kotaro, Shibata, Yasuhide, Inokuma, Keita, Watanabe, Tomoki, Yoneda, Yuki, Ide, Satoshi, Maeda, Tomoya, Ichino   +6 more
core   +2 more sources

Biosynthesis of the Thiamin-Thiazole in Eukaryotes: Identification of a Thiazole Tautomer Intermediate

, 2016
Thiamin thiazole biosynthesis in eukaryotes is still not completely understood. In this report, a late intermediate, tightly bound to the active site of the Saccharomyces cerevisiae thiazole synthase, was identified as an adenylated thiazole tautomer ...
Tadhg P. Begley (170128), Steven E. Ealick (43371), Frank C. Schroeder (159898), Christopher T. Jurgenson (2422837), Abhishek Chatterjee (1919224)   +4 more
core   +1 more source

Bioactive thiazole and benzothiazole derivatives

European Journal of Medicinal Chemistry, 2015
The heterocycles are the versatile compounds existing in almost all natural products and synthetic organic compounds, usually associated with one or the other biological activity. Among the heterocycles the thiazoles and benzothiazoles occupy a prominent position.
Rouf, Abdul, Tanyeli, Cihangir
openaire   +3 more sources