Results 81 to 90 of about 36,963 (239)

Beyond Protein Synthesis: The Multifunctional Role of Functional Amino Acids in Modulating Meat Quality in Ruminants

open access: yesAnimal Research and One Health, EarlyView.
Multifunctional roles of functional amino acids in regulating meat quality in ruminants: Functional amino acids (FAAs) regulate ruminant meat quality through multiple interconnected mechanisms, including antioxidant protection, metabolic regulation, signal transduction, structural support, and gene expression modulation.
Zixin Liu   +5 more
wiley   +1 more source

(E)-N′-(4-Fluorobenzylidene)-5-methyl-2-(pyridin-3-yl)thiazole-4-carbohydrazide

open access: yesMolbank, 2019
5-methyl-2-(pyridin-3-yl)-1,3-thiazole-4-carbohydrazide (1) on treatment with 4-fluorobenzaldehyde in presence of catalytic amount of acetic acid, accessed the target compound (2) with the yield of 79%.
Vinuta Kamat   +2 more
doaj   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon   +3 more
wiley   +1 more source

Synthesis of benzofuro[6,7-d]thiazoles, benzofuro[7,6-d]thiazoles and 6-arylaminobenzo[d]thiazole-4,7-diones as antifungal agent

open access: yes, 2018
Antifungal; Antimicrobial; Benzofuro[6,7-d]thiazole; Benzofuro[7,6-d]thiazole; Benzo[d]thiazole-4,7- dione ...
유충규
core   +1 more source

Biomimetic N‐cyano sulfoximine–thiazole ligation for antibody–drug conjugate assembly

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Biomimetic N‐cyano sulfoximine–thiazole ligation is applied for the first time to antibody–drug conjugate assembly. Installation of a sulfoximine handle on trastuzumab followed by ligation with a cysteine‐functionalized payload affords model ADCs with tunable drug‐to‐antibody ratios of 2–8 under mild aqueous conditions.
Eunsil Kim   +7 more
wiley   +1 more source

Inhibition of copper corrosion using thiazole derivative

open access: yes, 2015
The inhibitor efficiency of 5-(4'-dimetylaminobenzylidene)-2,4-dioxotetrahydro-1,3-thiazole, DABDT, against copper corrosion in acidic sulfate solution (0.1moldm-3 Na2SO4 at pH=3) was investigated applying the electrochemical impedance spectroscopy (EIS)
Borko Matijević, Abdul Shaban
core   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

open access: yesChemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens   +3 more
wiley   +1 more source

SCF MO Calculations for 1,3-Thiazole and 2-Phenyl-1,3- thiazole and Rotational Barriers in 2-Phenyl-1,3-thiazole and Its Protonated Form [PDF]

open access: yes, 1971
SCF MO calculations show that 2-phenyl-1,3-thiazole exists in planar configuration, while protonated 2-phenyl-1,3-thiazole tends to stabilize in a non-planar ...
Bodor, N., Farkas, M., Trinajstić, N.
core   +1 more source

Crystal structures of 6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione and 5′-methyl-6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2019
The title compounds, C20H16N2O3S, (I), and C21H18N2O3S, (II), differ by the presence of a methyl group in position 5 on the 1H-indole-2-one ring of compound (II). The two compounds have a structural overlap r.m.s. deviation of 0.48 Å.
S. Pangajavalli   +4 more
doaj   +1 more source

Red Blood Cell Surface Proteins and Cryopreservation for Tracking Altered Erythropoiesis

open access: yesDrug Testing and Analysis, EarlyView.
Recombinant human erythropoietin altered red blood cell surface protein expression, but responses were inconsistent and accompanied by substantial baseline variability. Although cryopreservation reduced analytical variability, it did not improve biomarker performance, indicating limited utility for detecting altered erythropoiesis. ABSTRACT The present
Martin Thomassen   +7 more
wiley   +1 more source

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