Results 71 to 80 of about 36,963 (239)

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

Angewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

Pharmaceutical perspectives of thiazole analogues: An overview

Results in Chemistry
Thiazole derivatives have attracted considerable attention in medicinal chemistry due to their promising biological activities. This review article provides a comprehensive overview on the pharmaceutical applications of the thiazole derivatives ...
Archana R. Patil, Basappa C. Yallur, Sampath Chinnam, Guddekoppa S. Ananthnag, C.R. Santhosh, Geetika Pant, S.G. Prasanna Kumar, Manjuanth D. Hadagali   +7 more
doaj   +1 more source

Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid

Molecules, 2007
A series of eight new azomethine derivatives were synthesized by reacting 2-formylphenoxyacetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of 1H-NMR, 13C-NMR, MS and elemental analysis.
George W. Weaver, Matloob Ahmad, C. M. Ashraf, Hamid Latif Siddiqui, Amjid Iqbal   +4 more
doaj   +1 more source

Quinoxaline Clubbed Thiazole-Supplementary data file

, 2023
Spectral data of Thiazole-quinoxaline derivatives (3a-3j).
Pravin Tryambake (17425920), Sagar Shrimandilkar (17180533), Keshao Mahale (17425931), Dnyaneshwar Lokhande (17425915)   +3 more
core   +1 more source

Synthesis and biological activity evaluation of new functionally substituted 5-arylidene-2,4-dioxotetrahydro-1,3-thiazoles [PDF]

Journal of the Serbian Chemical Society, 2006
New functionally substituted 5-arylidene-2,4-dioxotetrahydro-1,3-thiazole-3-carboxylic acid cholesteryl esters were synthesized from 2,4-dioxotetrahydro-1,3-thiazole and evaluated for their in vitro cytotoxicity against several human tumor cell lines and
MIROSLAV PERGAL, MILICA RANCIC, KATARINA POPOV-PERGAL, GORDANA BOGDANOVIC, VESNA KOJIC, DEJAN DJOKOVIC   +5 more
doaj  

Some Studies in Sulfadiazine Incorporating Pyridine, Pyrimidine, Oxadiazole, and Azo Moieties Endowed with Pharmaceutical Potency

Acta Chimica Slovenica, 2020
A set of substituted sulfadiazine compounds was prepared as cytotoxic and antitumor agents by using 4-amino-N-(pyrimidin-2-yl)benzenesulfonamide (1) as the starting material.
Sherihan El-Hadidy, Sraa Abu-Melha
doaj   +1 more source

Thiazoles in glycosylation reactions: Novel synthesis of thiazole thioglycosides

Heteroatom Chemistry, 2017
Abstract This research reports a novel method for synthesizing new thiazole thioglycosides. This series of thiazole thioglycosides were designed by the reaction of potassium cyanocarbonimidodithioate 2 with benzoyl acetonitrile 3a and ...
Mamdouh A. Abu‐Zaied, Galal H. Elgemeie   +1 more
openaire   +1 more source

Comprehensive review on coumarin–thiazole hybrids: Synthesis, characterization, in silico studies, and biological perspectives

Bulletin of Pharmaceutical Sciences. Assiut University
The hybrid molecules with various pharmacological actions are believed to emerge on the combination of coumarin and thiazole scaffolds. The bioactive scaffolds of coumarin and thiazole comprise such derivatives and have a broad spectrum of biological ...
Noor Abd Alhassan, Leaqaa Abd Ridha
doaj   +1 more source

6′-(3-Bromophenyl)-7′-nitro-1′,6′,7′,7a'-tetrahydro-3′H-spiro[indeno[1,2-b]quinoxaline-11,5′-pyrrolo[1,2-c]thiazole]

IUCrData, 2018
The title compound, C26H19BrN4O2S, crystallizes in a monoclinic C-centred lattice with eight molecules in the unit cell. The five-membered thiazole and pyrrolidine rings adopt envelope conformations and the bromophenyl and indenoquinoxaline planes are ...
C. Muthuselvi, M. Muthu, S. Athimoolam, B. Ravikumar, S. Pandiarajan, R. V. Krishnakumar   +5 more
doaj   +1 more source

Synthesis of oligonucleotides containing thiazole and thiazole N-oxide nucleobases

, 2002
[reaction: see text] The thiazole C-nucleoside analogue was synthesized by the Hantzsch cyclization method to form the thiazole ring and was then converted to the thiazole N-oxide C-nucleoside analogue by peracid oxidation of the heterocycle nitrogen ...
Fronczek, Frank R, Sheybani, Arsham, Tallini, Camille E, Miller, Tod J, Saurage, Andrea S, Hammer, Robert P, Farquar, Hannah D, Tod J. Miller, Arsham Sheybani, Hannah D. Farquar, Camille E. Tallini, Andrea S. Saurage, Robert P. Hammer, Frank R. Fronczek   +13 more
core   +1 more source