Results 71 to 80 of about 46,327 (259)

4-[Bis(thiazol-2-ylamino)methyl]phenol

Molbank, 2023
We have designed and synthesized novel bis-thiazole derivative. A 4-[bis(thiazol-2-ylamino)methyl]phenol was efficiently prepared in 71% yield by the reaction of 2-aminothiazole with 4-hydroxybenzaldehyde in ethanol for 24 h.
Joanna Cytarska, Anna Kolasa
doaj   +1 more source

A comprehensive review on thiazole derivatives as multifunctional therapeutics

Discover Chemistry
Thiazole, a versatile five-membered heterocyclic scaffold containing sulfur and nitrogen atoms, has emerged as a pivotal pharmacophore in medicinal chemistry due to its unique chemical properties and broad spectrum of biological activities.
Dattatray N. Thorat, Krutika S. Sonar, Sandip R. Kale, Anoop Singh, Sandip D. Patil, Pramodkumar Awasthi   +5 more
doaj   +1 more source

Inclusion of a Catechol-Derived Hydrazinyl-Thiazole (CHT) in β-Cyclodextrin Nanocavity and Its Effect on Antioxidant Activity: A Calorimetric, Spectroscopic and Molecular Docking Approach

Antioxidants, 2023
The aim of the present research was to obtain a supramolecular complex between a strong antioxidant compound previously reported by our group, in order to extend its antioxidant activity.
Mihaela Mic, Adrian Pîrnău, Călin G. Floare, Mariana Doina Palage, Ovidiu Oniga, Gabriel Marc   +5 more
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of 4-(naphthalen-2-yl)-N-[(Z)-4-propoxybenzylidene]-1,3-thiazol-2-amine

Acta Crystallographica Section E: Crystallographic Communications, 2020
The asymmetric unit of the title compound, C23H20N2OS, contains one slightly bent molecule. The naphthalene ring system and the thiazole ring are twisted with respect to each other, making a dihedral angle of 13.69 (10)°; the anisole ring is inclined to ...
Ropak A. Sheakh Mohamad, Wali M. Hamad, Hashim J. Aziz   +2 more
doaj   +1 more source

New thiazole, pyridine and pyrazole derivatives as antioxidant candidates: synthesis, DFT calculations and molecular docking study

Heliyon, 2020
Novel heterocyclic compounds containing pyrazole, thiazole and pyridine moieties were designed and prepared based on the condensation reaction between 1,3-thiazole or aminopyridine derivatives and 1H-pyrazole,3,5-dimethyl-1H-pyrazole or 1,2,4-triazole ...
Y. Kaddouri, F. Abrigach, E. B. Yousfi, M. El Kodadi, R. Touzani   +4 more
semanticscholar   +1 more source

Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (Mpro)

Molecules, 2020
A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop grinding of thiazole carbohydrazide 2 with various carbonyl compounds.
Sraa Abu-Melha, M. M. Edrees, S. Riyadh, Mohamad R. Abdelaziz, Abdo A. Elfiky, Sobhi M. Gomha   +5 more
semanticscholar   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid

Molecules, 2007
A series of eight new azomethine derivatives were synthesized by reacting 2-formylphenoxyacetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of 1H-NMR, 13C-NMR, MS and elemental analysis.
George W. Weaver, Matloob Ahmad, C. M. Ashraf, Hamid Latif Siddiqui, Amjid Iqbal   +4 more
doaj   +1 more source

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Pharmaceutical perspectives of thiazole analogues: An overview

Results in Chemistry
Thiazole derivatives have attracted considerable attention in medicinal chemistry due to their promising biological activities. This review article provides a comprehensive overview on the pharmaceutical applications of the thiazole derivatives ...
Archana R. Patil, Basappa C. Yallur, Sampath Chinnam, Guddekoppa S. Ananthnag, C.R. Santhosh, Geetika Pant, S.G. Prasanna Kumar, Manjuanth D. Hadagali   +7 more
doaj   +1 more source