Results 51 to 60 of about 36,963 (239)
Overview on Biological Activities of Thiazole Derivatives [PDF]
Records of Pharmaceutical & Biomedical SciencesThiazole and its derivatives have garnered widespread attention in medicinal chemistry due to their remarkable range of biological activities. This heterocyclic scaffold is characterized by a five-membered aromatic ring that incorporates both nitrogen ...
Omnia Beker +3 more
doaj +1 more source
, 2016 In this paper we report three thiazole-flanked diketopyrrolopyrrole-based donor–acceptor alternating copolymers as new ambipolar semiconductors and their field-effect transistor devices with balanced hole and electron mobilities.
Weifeng Zhang (134361) +5 more
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Effect of Thiazole Derivatives on Copper Corrosion in Acidic Sulphate Solution
International Journal of Electrochemical Science, 2015 Inhibition of copper corrosion in 0.1 mol dm-3 Na2SO4 solution (pH 3) by two thiazole derivatives of 5-(5'-methylfurfurylidene-2')-2,4-dioxotetrahydro-1,3-thiazole (MFDT) and 2-thiono-5-(4'-ethoxybenzylidene)-4-oxotetrahydro-1,3-thiazole (TEBOT) was ...
Jelena Nakomčić +3 more
doaj +1 more source
Synthesis of 5-β-D-ribofuranosyl-1,3-thiazole-2-carboxamide - A thiazole analogue of ribavirin
, 1979 Condensation of ethyl thioxamate (II) with bromomethyl D-ribo-1,2,3,4-tetraacetoxybutyl ketone (I) or bromomethyl 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl ketone (IX) afforded ethyl 5-(D-ribo-1,2,3,4-tetraacetoxybutyl)-1,3-thiazole-2-carboxylate (III) and ...
Jiří Gut +2 more
core +1 more source
ChemistryOpenSelective binding of small molecule ligands to nucleic acids with high affinity and limited toxicity remains an important goal in the development of compounds that can probe DNA or RNA in cells.
Antwine W. McFarland Jr. +10 more
doaj +1 more source
Diethylene Glycol-Linked Ring-Fused Bis-Azoles: Target-Oriented Synthesis, In Silico Screening, and Antitumor Activity. [PDF]
ChemMedChemA series of diethylene glycol‐linked cyclic derivatives with diversity in the heterocyclic motif have been synthesized and screened for antitumor activity. Two bis‐thiazolo[3,2‐a]pyrimidinone derivatives displayed moderate cytotoxicity, high selectivity against hepatocellular carcinoma cells, promising VEGFR2, and remarkable FGFR2 inhibitory activities
Al-Hussain SA +6 more
europepmc +2 more sources
, 1981 [Anilino-2 méthyl-4 N-méthyl-anilino-5 thiazole-1,3 et anilino-2 N-méthylanilino-5 phenyl-4 thiazole-1,3 (deux dérivés du thiazole-1,3)
Henriet, Marielle +5 more
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6-Bromo-2-methylsulfanyl-1,3-benzothiazole
Acta Crystallographica Section E, 2011 The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS ...
Michał A. Dobrowolski +2 more
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SYNTHESIS OF SOME NEW 2,4,6-TRISUBSTITUTEDTHIAZOLO-[5,4-d] PYRIMIDINE-5,7(4H,6H)-DIONES.
Zagazig Journal of Pharmaceutical Sciences, 1999 Reaction of 2,6-disubstitutedthiazolo5,4-dpyrimidin-7(6H)-ones 2 with ethyl chloroformate/ethanol mixture afforded 5-(ethoxycarbonylamino) -2-(substitutedthio) thiazole-4-(N-substituted)-carboxamides 4a-c.
Wahid Basyouni , Hanaa Hosni
doaj +1 more source
Synthesis of the thiazole-thiazoline fragment of largazole analogues
, 2011 The thiazole-thiazoline fragment of the marine natural product largazole, a potent histone deacetylase 1 inhibitor, has been synthesized in five steps.
Nielsen, Daniel Skovhaur +5 more
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