Results 21 to 30 of about 49,222 (248)

Activity of antioxidant enzymes in hepatocytes of mice with lymphoma under the action of thiazole derivative in complex with polymeric nanocarrier

Біологія тварин, 2023
Many chemotherapeutics drugs have low water solubility, which potentially can decrease their anticancer potential. The use of drug delivery systems has proven to be highly effective in addressing the challenges associated with delivering hydrophobic ...
B. Omeliukh, Ya. Shalai, M. Bura, M. Ilkiv, Yu. Ostapiuk, N. Mitina, O. Zaichenko, A. Babsky   +7 more
doaj   +1 more source

Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts [PDF]

, 2013
Platinum diam(m)ine complexes, such as cisplatin, are successful anticancer drugs, but suffer from problems of resistance and side-effects. Photoactivatable PtIV prodrugs offer the potential of targeted drug release and new mechanisms of action.
Bancroft, Brabec, Brabec, Brabec, Butler, Caradonna, Coluccia, Dhara, Eastman, Eastman, Farrell, Farrer, Farrer, Fichtinger-Schepman, Guddneppanavar, Hall, Hamers, Harper, Intini, Jamieson, Kasparkova, Kasparkova, Kauffman, Keck, Kelland, Lau, Lemaire, Mackay, Mackay, Mackay, Najajreh, Ohndorf, O’Dwyer, Pantoja, Phillips, Pracharova, Pregosin, Prokop, Reedijk, Ronconi, Salassa, Salassa, Salassa, Salassa, Siddik, Stehlíková, Still, Suchánková, Tai, Vinje, Vlček, Wang, Westendorf, Westendorf, Westendorf, Wong, Yao, Zenker   +57 more
core   +1 more source

Demethylation and desulfonation of textile industry dye, Thiazole Yellow G by Aspergillus niger LAG

Biotechnology Reports, 2019
Filamentous fungi perform tremendously in adsorption of dyes from polluted environment. In this study, Aspergillus niger LAG decolorized thiazole yellow G dye within 5 days. Scale up studies done revealed that maximum decolorization (98%) was achieved at
Paul O. Bankole, Adedotun A. Adekunle, Sanjay P. Govindwar   +2 more
doaj   +1 more source

Synthesis of camphor thiazole derivates from Dryobalanops aromatica and its bioactivity as antioxidants and antidiabetes against alpha glucosidase enzymes

MethodsX, 2023
Camphor is synthesized from the Sumatran camphor plant (Dryobalanops aromatica) in previous experiments. It can be synthesized with thiosemicarbazide, ethy-2‑chloro acetoacetate, and sodium acetate (catalyze) to form camphor derivate with thiazole ring ...
Antonius Herry Cahyana, Gusman Santika, Kandarpa Phukan   +2 more
doaj   +1 more source

Synthesis and biological activity evaluation of new functionally substituted 5-arylidene-2,4-dioxotetrahydro-1,3-thiazoles [PDF]

Journal of the Serbian Chemical Society, 2006
New functionally substituted 5-arylidene-2,4-dioxotetrahydro-1,3-thiazole-3-carboxylic acid cholesteryl esters were synthesized from 2,4-dioxotetrahydro-1,3-thiazole and evaluated for their in vitro cytotoxicity against several human tumor cell lines and
MIROSLAV PERGAL, MILICA RANCIC, KATARINA POPOV-PERGAL, GORDANA BOGDANOVIC, VESNA KOJIC, DEJAN DJOKOVIC   +5 more
doaj   +3 more sources

Thiazole, triazole, thio- and semicarbazone derivatives - Promising moieties for drug development for the treatment of tuberculosis

European Journal of Medicinal Chemistry Reports, 2021
Thiazole, triazole, thio and semicarbazones are privileged motifs that act as pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB).
Cauê Benito Scarim, Fernando Rogério Pavan   +1 more
doaj   +1 more source

Molecular modeling and docking of new 2-acetamidothiazole-based compounds as antioxidant agents

Journal of Saudi Chemical Society, 2022
The highly versatile, 2-chloroacetamido-5-(4-chlorophenylazo)thiazole (2) was synthesized and used as a precursor for the production of five 2-(2-substitutedacetamido)thiazole compounds by its reaction with different types of nucleophiles such as ...
Sraa Abu-Melha
doaj   +1 more source

Methyl 2-amino-5-iso­propyl-1,3-thia­zole-4-carboxyl­ate [PDF]

, 2004
The title compound, C8H12N2O2S, forms a supramolecular network based on N-HN hydrogen-bonded centrosymmetric dimers that are linked in turn by N-HO ...
Kennedy, Alan R., Khalaf, Abedawn I., Suckling, Colin J., Waigh, Roger D.   +3 more
core   +1 more source

Design, Synthesis and Cytotoxicity of Thiazole-Based Stilbene Analogs as Novel DNA Topoisomerase IB Inhibitors

Molecules, 2022
A series of new thiazole-based stilbene analogs were designed, synthesized and evaluated for DNA topoisomerase IB (Top1) inhibitory activity. Top1-mediated relaxation assays showed that the synthesized compounds possessed variable Top1 inhibitory ...
Jin-Chuan Liu, Bo Chen, Jia-Lin Yang, Jian-Quan Weng, Qian Yu, De-Xuan Hu   +5 more
doaj   +1 more source

2-(Benzothiazol-2-ylsulfanyl)acetic acid

Acta Crystallographica Section E, 2010
In the title compound, C9H7NO2S2, the benzine ring is essentially co-planar with the thiazole ring, making a dihedral angle of 0.36 (7)°. In the crystal structure, molecules are linked by intermolecular O—H...N hydrogen bonds
Zhi-li Fang, Jun Wang
doaj   +1 more source