Results 11 to 20 of about 46,327 (259)

Synthesis, modeling, and biological studies of new thiazole-pyrazole analogues as anticancer agents

open access: yesJournal of Saudi Chemical Society, 2023
A series of various substituted thiazole-pyrazole hybrids 5, 7, 8, and 9 were synthesized, and their chemical structures were confirmed by spectral data (infrared, 1H & 13C NMR and Mass).
Gadeer R.S. Ashour   +7 more
doaj   +2 more sources

Antiproliferative activity of thiazole and oxazole derivatives: A systematic review of in vitro and in vivo studies

open access: yesBiomedicine and Pharmacotherapy, 2021
Thiazole and oxazole are compounds with a heterocyclic nucleus that have attracted the attention of medicinal chemistry due to the great variety of biological activities that they enable.
Sepulveda-Arias Jc, Luz Angela Veloza
exaly   +2 more sources

Synthesis and Biological Evaluation of 2-Aminothiazole Analogues of Nα-Protected Amino Acids [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2023
Synthesis of 2-amino-thiazoles from Nα-protected bromomethyl ketones obtained from Nα-protected diazomethyl ketones has been reported in this study.N-protected amino acids were converted to diazomethylketones using (Benzotriazol-1-yloxy) tris ...
Lalithamba Haraluru Shankaraiah   +3 more
doaj   +1 more source

Synthesis of Thiazole-2(3H)-thiones as Antimicrobial Agents Promoted by H3PW12O40-amino-functionalized CdFe12O19@SiO2 Nanocomposite [PDF]

open access: yesNanochemistry Research, 2022
H3PW12O40-amino-functionalized CdFe12O19@SiO2 nanocomposite has been utilized as an effective nanocatalyst for the preparation of thiazole-2(3H)-thiones by three-component reactions of CS2, 2-bromoacetophenone or 2-bromo-1-(4-methoxyphenyl) ethenone, and
Hossein Shahbazi-Alavi   +1 more
doaj   +1 more source

Synthesis and Structural Confirmation of the Thiazole Alkaloids Derived from Peganum harmala L.

open access: yesApplied Sciences, 2021
Peganumal A and B are thiazole alkaloids isolated from the seeds of Peganum harmala L. Thiazole moieties are rarely found in natural products, but diverse compounds possessing thiazole moieties have attracted attention owing to their broad range of ...
Myeonghyeon Sim   +2 more
doaj   +1 more source

5-Chloro-6-oxo-6H-xantheno[4,3-d]thiazole-2-carbonitrile

open access: yesMolbank, 2022
Xanthones and benzothiazoles are important classes of heterocyclic compounds with versatile biological activities. Herein, we describe a straightforward and scalable synthesis of 5-chloro-6-oxo-6H-xantheno[4,3-d]thiazole-2-carbonitrile, a thiazole-fused ...
Konstantinos Paraskevas   +3 more
doaj   +1 more source

Theoretical investigations on the HOMO–LUMO gap and global reactivity descriptor studies, natural bond orbital, and nucleus-independent chemical shifts analyses of 3-phenylbenzo[d]thiazole-2(3H)-imine and its para-substituted derivatives: Solvent and substituent effects

open access: yes, 2021
Natural bond orbital analysis, salvation, and substituent effects of electron-releasing (–CH3, –OH) and electron-withdrawing (–Cl, –NO2, –CF3) groups at para positions on the molecular structure of synthesized 3-phenylbenzo[d]thiazole-2(3H)-imine and its
Marzieh Miar   +4 more
semanticscholar   +1 more source

A Thiazole-linked Covalent Organic Framework for Lithium-Sulphur Batteries.

open access: yesAngewandte Chemie, 2023
Lithium-sulphur (Li-S) batteries are a promising alternative power source, as they can provide a higher energy density than current lithium-ion batteries.
Rui Yan   +9 more
semanticscholar   +1 more source

In Vitro Inhibition Effects of 2-Amino Thiazole Derivatives on Lactoperoxidase Enzyme Activity

open access: yesCumhuriyet Science Journal, 2022
Lactoperoxidase (LPO E.C. 1.11.1.7) is a member of the peroxidase family and is an important glycoprotein containing heme group in its structure and showing the antimicrobial effect on disease causing microorganisms in the digestive system of newborn ...
Işıl Nihan Korkmaz
doaj   +1 more source

Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells. [PDF]

open access: yesPLoS ONE, 2009
Forkhead box M1 (FoxM1) oncogenic transcription factor represents an attractive therapeutic target in the fight against cancer, because it is overexpressed in a majority of human tumors.
Uppoor G Bhat   +2 more
doaj   +1 more source

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