Results 11 to 20 of about 36,963 (239)

Synthesis of 2,3-dihydronaphtho[2,3-d][1,3]thiazole-4,9-diones and 2,3-dihydroanthra[2,3-d][1,3]thiazole-4,11-diones and novel ring contraction and fusion reaction of 3H-spiro[1,3-thiazole-2,1'-cyclohexanes] into 2,3,4,5-tetrahydro-1H-carbazole-6,11-diones

Beilstein Journal of Organic Chemistry, 2013
Treatment of N-substituted 2-(methylamino)naphthoquinones 3 and -anthracene-1,4-diones 4 with S2Cl2 and DABCO in chlorobenzene gave the corresponding 2,3-dihydronaphtho[2,3-d][1,3]thiazole-4,9-diones 1 and 2,3-dihydroanthra[2,3-d][1,3]thiazole-4,11 ...
Lidia S. Konstantinova, Kirill A. Lysov, Ljudmila I. Souvorova, Oleg A. Rakitin   +3 more
doaj   +2 more sources

Thiazole-induced rigidification in substituted dithieno-tetrathiafulvalene: The effect of planarisation on charge transport properties [PDF]

, 2015
© 2015 Taylor et al; licensee Beilstein-Institut.Two novel tetrathiafulvalene (TTF) containing compounds 1 and 2 have been synthesised via a four-fold Stille coupling between a tetrabromo-dithienoTTF 5 and stannylated thiophene 6 or thiazole 4.
Olena Avramchenko (7163237), Joseph Cameron (7034792), Anto R. Inigo (1355796), Rupert G.D. Taylor (7163051), Neil Thomson (440509), Iain Wright (3281406), Alexander L. Kanibolotsky (1340457), Tell Tuttle (1273947), Peter J. Skabara (1266399)   +8 more
core   +4 more sources

Synthesis, Anticancer and Antimicrobial Screening of New Naphthalenyl-Thiazole and Quinolinyl-Thiazole

, 2021
A new series of 4-aryl-2-(naphthalen-1-yl)thiazole (7a-b), 4-aryl/pyridyl-2-(2-substituted quinolin-4-yl)thiazole (13a-o) and 4-(pyridin-4-yl)-2-(quinolin-4-yl)thiazole (15) have been synthesized.
Yogita Abhale (11576400), Krishna Borde (11576397), Vivek Bobade (11576403), Pravin C. Mhaske (9857764), Yogesh Walunj (11576391), Abhijit Shinde (11576394)   +5 more
core   +1 more source

Thiazole-5-carbaldehyde Synthesis by Cascade Annulation of Enaminones and KSCN with Dess–Martin Periodinane Reagent

, 2022
The Dess–Martin periodinane (DMP) reagent-mediated reactions of tertiary enaminones with potassium thiocyanate for the synthesis of thiazole-5-carbaldehydes are developed.
Kang Chen (285159), Jie-Ping Wan (1393846), Yunyun Liu (538796), Baoli Zhao (1957888)   +3 more
core   +1 more source

Thiazole orange-carboplatin triplex-forming oligonucleotide (TFO) combination probes enhance targeted DNA crosslinking

, 2023
We report a new class of carboplatin-TFO hybrid that incorporates a bifunctional alkyne–amine nucleobase monomer called AP-C3-dT that enables dual ‘click’ platinum(II) drug conjugation and thiazole orange fluorophore coupling.
Klimkowski, Piotr, Gibney, Alex, Kellett, Andrew, Hennessy, Joseph, Singleton, Daniel, Brown, Tom, Farrell, Nicholas P, Coche, Malou, El-Sagheer, Afaf H   +8 more
core   +2 more sources

Stereoselective synthesis, X-ray analysis, computational studies and biological evaluation of new thiazole derivatives as potential anticancer agents

Chemistry Central Journal, 2018
Background The synthesis of new thiazole derivatives is very important because of their diverse biological activities. Also , many drugs containing thiazole ring in their skeletons are available in the market such as Abafungin, Acotiamide, Alagebrium ...
Yahia N. Mabkhot, Mohammed M. Alharbi, Salim S. Al-Showiman, Hazem A. Ghabbour, Nabila A. Kheder, Saied M. Soliman, Wolfgang Frey   +6 more
doaj   +1 more source

Medicinal Chemistry Aspects of Thiazole and Thiazolidine Derivatives as Fundamental Building Blocks to Design New NNRTIs Against HIV-1 Reverse Transcriptase. [PDF]

ChemMedChem
HIV‐1 reverse transcriptase (HIV‐1 RT) is a polymerase enzyme and a key target in HIV‐1 therapy. The discovery of selective HIV‐1 RT inhibitors has highlighted thiazole scaffolds and their derivatives, thiazolidine‐2‐one and thiazolidine‐2,4‐dione, as promising structures for the rational design of novel non‐nucleoside reverse transcriptase inhibitors (
da Silva Moura JA, de Melo MVG, do Nascimento DRS, Bezerra TPW, Métifiot M, Recordon-Pinson P, da Rocha Pitta MG, da Rocha Pitta MG, Pereira MC, Andreola ML.   +9 more
europepmc   +2 more sources

Thiazoles and Thiazolidinones as Antioxidants

Current Medicinal Chemistry, 2013
Antioxidants are of great interest because of their involvement in important biological and industrial processes. According to Halliwell antioxidants are substances that at low concentration significantly delay or prevent oxidation. Chemically, oxidation is a process in which a loss of electrons occurs.
Geronikaki, Athina, Pitta, Eleni, Liaras, Konstantinos   +2 more
openaire   +3 more sources

Activity of antioxidant enzymes in hepatocytes of mice with lymphoma under the action of thiazole derivative in complex with polymeric nanocarrier

Біологія тварин, 2023
Many chemotherapeutics drugs have low water solubility, which potentially can decrease their anticancer potential. The use of drug delivery systems has proven to be highly effective in addressing the challenges associated with delivering hydrophobic ...
B. Omeliukh, Ya. Shalai, M. Bura, M. Ilkiv, Yu. Ostapiuk, N. Mitina, O. Zaichenko, A. Babsky   +7 more
doaj   +1 more source

Synthesis of camphor thiazole derivates from Dryobalanops aromatica and its bioactivity as antioxidants and antidiabetes against alpha glucosidase enzymes

MethodsX, 2023
Camphor is synthesized from the Sumatran camphor plant (Dryobalanops aromatica) in previous experiments. It can be synthesized with thiosemicarbazide, ethy-2‑chloro acetoacetate, and sodium acetate (catalyze) to form camphor derivate with thiazole ring ...
Antonius Herry Cahyana, Gusman Santika, Kandarpa Phukan   +2 more
doaj   +1 more source