Results 11 to 20 of about 9,421 (215)

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications [PDF]

open access: yesAngewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika   +9 more
wiley   +3 more sources

2,4,5-Tris(pyridin-4-yl)-4,5-dihydro-1,3-oxazole

open access: yesActa Crystallographica Section E, 2012
In the title compound, C18H14N4O, the molecules are disordered about a crystallographic twofold axis, leading to 50:50 disorder of the O- and N-atom sites within the oxazole ring. As a consequence, symmetry-related oxazole C—N and C—O
José J. Campos-Gaxiola   +3 more
doaj   +2 more sources

Therapeutic Potential of Isoxazole–(Iso)oxazole Hybrids: Three Decades of Research [PDF]

open access: yesInt J Mol Sci
Heterocyclic compounds are a common subject in the field of medicinal chemistry due to their numerous pharmaceutical applications. Among these, nitrogen- and oxygen-containing five-membered heterocyclic rings, namely oxazole and isoxazole, are ...
Marcin Mączyński   +2 more
core   +2 more sources

A BRIEF REVIEW ON ANTIMICROBIAL ACTIVITY OF OXAZOLE DERIVATIVES

open access: yes, 2022
The usefulness of oxazole as intermediates for the synthesis of new chemical entities in medicinal chemistry has been increased in the past few years.
Mrs. Sheeja Rekha A G , Dr. Prasobh G R, Mrs. Athira A S, Mrs. Anila Kumari V S, Mrs. Seba M C, Mrs. Gini Jameena
core   +1 more source

A Route to Conjugated Monomers and Polymers Incorporating 2,5-Connected Oxazole in the Backbone

open access: yes, 2022
Joining of imidazole, pyrimidine, and oxazole to other conjugated core units was explored in pursuit of yielding monomers to synthesize organic semiconducting polymers.
Waner He (12274795)   +3 more
core   +1 more source

Synthesis, Characterization, and Anti-inflammatory activity of Some Novel Oxazole Derivatives [PDF]

open access: yes, 2023
A series of novel oxazole derivatives (A, A1, A2) were synthesized starting from acetone and urea. The compound (A) was obtained by heating it with acetophenone and urea in iodine.
Singh, Ranjan Kumar   +9 more
core   +1 more source

2-(Naphthalen-1-yl)-4-(thiophen-2-ylmethylidene)-1,3-oxazol-5(4H)-one

open access: yesActa Crystallographica Section E, 2011
The asymmetric unit of the title compound, C18H11NO2S, contains two crystallographically independent molecules. In one molecule, the oxazole and thiophene rings are oriented at dihedral angles of 17.40 (9) and 18.18 (7)° with
Cevher Gündoğdu   +4 more
doaj   +1 more source

Polarizability in Substituted Oxazoles: A PC-Model Data Analysis

open access: yesE-Journal of Chemistry, 2005
A systematic investigation of various Oxazole derivatives has been subjected to a Polarized Continuums Model (PCM) for evaluation of their physico-chemical parameters.
S. Harikrishna   +3 more
doaj   +1 more source

Computational Redesign of Bacterial Biotin Carboxylase Inhibitors Using Structure-Based Virtual Screening of Combinatorial Libraries

open access: yesMolecules, 2014
As the spread of antibiotic resistant bacteria steadily increases, there is an urgent need for new antibacterial agents. Because fatty acid synthesis is only used for membrane biogenesis in bacteria, the enzymes in this pathway are attractive targets for
Michal Brylinski, Grover L. Waldrop
doaj   +1 more source

Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising Acetylcholinesterase and Butyrylcholinesterase Inhibitors

open access: yesMolecules, 2023
Alzheimer’s disease (AD) is a degenerative neurological condition that severely affects the elderly and is clinically recognised by a decrease in cognition and memory.
Rafaqat Hussain   +7 more
doaj   +1 more source

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