Results 11 to 20 of about 5,801 (188)

A comprehensive review on biological activities of oxazole derivatives

BMC Chemistry, 2019
The utility of oxazole as intermediates for the synthesis of new chemical entities in medicinal chemistry have been increased in the past few years. Oxazole is an important heterocyclic nucleus having a wide spectrum of biological activities which drew ...
Saloni Kakkar, Balasubramanian Narasimhan   +1 more
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2,4,5-Tris(pyridin-4-yl)-4,5-dihydro-1,3-oxazole

Acta Crystallographica Section E, 2012
In the title compound, C18H14N4O, the molecules are disordered about a crystallographic twofold axis, leading to 50:50 disorder of the O- and N-atom sites within the oxazole ring. As a consequence, symmetry-related oxazole C—N and C—O
José J. Campos-Gaxiola, Herbert Höpfl, Gerardo Aguirre, Miguel Parra-Hake   +3 more
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2-(Naphthalen-1-yl)-4-(thiophen-2-ylmethylidene)-1,3-oxazol-5(4H)-one

Acta Crystallographica Section E, 2011
The asymmetric unit of the title compound, C18H11NO2S, contains two crystallographically independent molecules. In one molecule, the oxazole and thiophene rings are oriented at dihedral angles of 17.40 (9) and 18.18 (7)° with
Cevher Gündoğdu, Serap Alp, Yavuz Ergün, Barış Tercan, Tuncer Hökelek   +4 more
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Polarizability in Substituted Oxazoles: A PC-Model Data Analysis

E-Journal of Chemistry, 2005
A systematic investigation of various Oxazole derivatives has been subjected to a Polarized Continuums Model (PCM) for evaluation of their physico-chemical parameters.
S. Harikrishna, S. P. Shrivastava, J. T. Rao, S. N. Limaye   +3 more
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Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising Acetylcholinesterase and Butyrylcholinesterase Inhibitors

Molecules, 2023
Alzheimer’s disease (AD) is a degenerative neurological condition that severely affects the elderly and is clinically recognised by a decrease in cognition and memory.
Rafaqat Hussain, Fazal Rahim, Hayat Ullah, Shoaib Khan, Maliha Sarfraz, Rashid Iqbal, Faiza Suleman, Mohammad Khalid Al-Sadoon   +7 more
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Computational Redesign of Bacterial Biotin Carboxylase Inhibitors Using Structure-Based Virtual Screening of Combinatorial Libraries

Molecules, 2014
As the spread of antibiotic resistant bacteria steadily increases, there is an urgent need for new antibacterial agents. Because fatty acid synthesis is only used for membrane biogenesis in bacteria, the enzymes in this pathway are attractive targets for
Michal Brylinski, Grover L. Waldrop
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2-(Naphthalen-1-yl)-4-(naphthalen-1-ylmethylidene)-1,3-oxazol-5(4H)-one

Acta Crystallographica Section E, 2011
In the title compound, C24H15NO2, the oxazole ring is oriented at dihedral angles of 10.09 (4) and 6.04 (4)° with respect to the mean planes of the naphthalene ring systems, while the two naphthalene ring systems make a ...
Cevher Gündoğdu, Serap Alp, Yavuz Ergün, Barış Tercan, Tuncer Hökelek   +4 more
doaj   +1 more source

Evaluation of the Interaction between Long Telomeric DNA and Macrocyclic Hexaoxazole (6OTD) Dimer of a G-quadruplex Ligand

Molecules, 2013
Macrocyclic hexaoxazole dimer of L2H2-6OTD-dimer (3) was newly synthesized as a telomeric G-quadruplex (G4) ligand, and interaction with long telomeric DNAs telo48, 72, and 96 was evaluated by means of electrophoresis mobility shift assay, CD spectra ...
Kazuo Nagasawa, Hiroyuki Seimiya, Takahiro Nakamura, Satoki Majima, Keisuke Iida   +4 more
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Theoretical structural study of van der Waals complexes between oxazole and atmospheric gases CO2 and N2 for capture applications. [version 2; peer review: 2 approved, 1 approved with reservations]

Open Research Europe
Background The objective of this study is to explore the potential of oxazole (C3H3NO), a fascinating heterocyclic compound naturally present, which is a potential ligand in the construction of Metal-Organic Frameworks (MOFs) for the selective capture of
A. Belasri, O. Douass, F. Tahiri, M. Belmouden, N. Inostroza-Pino, M. Mogren Al-Mogren, H. Bahmann, S. Dalbouha, M. L. Senent   +8 more
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Novel Pyridyl–Oxazole Carboxamides: Toxicity Assay Determination in Fungi and Zebrafish Embryos

Molecules, 2021
Eight novel pyridyl–oxazole carboxamides were evaluated against fungi and displayed good fungicidal activities against Botrytis cinereal and Rhizoctonia solani. Preliminary bioassay results indicated that at 100 mg/L, compounds 6a–6e, 6g and 6h exhibited
Shu Chen, Dong-Lin Zhang, Chao-Li Ren, Wen-Qian Zou, Xiao-Yu Tian, Xiao-Hua Du, Cheng-Xia Tan   +6 more
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