Results 21 to 30 of about 5,801 (188)

Theoretical structural study of van der Waals complexes between oxazole and atmospheric gases CO2 and N2 for capture applications. [version 3; peer review: 2 approved, 1 approved with reservations]

Open Research Europe
Background The objective of this study is to explore the potential of oxazole (C3H3NO), a fascinating heterocyclic compound naturally present, which is a potential ligand in the construction of Metal-Organic Frameworks (MOFs) for the selective capture of
A. Belasri, O. Douass, F. Tahiri, M. Belmouden, N. Inostroza-Pino, M. Mogren Al-Mogren, H. Bahmann, S. Dalbouha, M. L. Senent   +8 more
doaj   +1 more source

New N-(oxazolylmethyl)-thiazolidinedione Active against Candida albicans Biofilm: Potential Als Proteins Inhibitors

Molecules, 2018
C. albicans is the most frequently occurring fungal pathogen, and is becoming an increasing public health problem, especially in the context of increased microbial resistance. This opportunistic pathogen is characterized by a versatility explained mainly
Gabriel Marc, Cătălin Araniciu, Smaranda Dafina Oniga, Laurian Vlase, Adrian Pîrnău, Mihaela Duma, Luminița Măruțescu, Mariana Carmen Chifiriuc, Ovidiu Oniga   +8 more
doaj   +1 more source

Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms

Molecules, 2021
Coumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules ...
Eslam Reda El-Sawy, Ahmed Bakr Abdelwahab, Gilbert Kirsch   +2 more
doaj   +1 more source

Crystal structure, Hirshfeld surface analysis and DFT study of (2Z)-2-(2,4-dichlorobenzylidene)-4-[2-(2-oxo-1,3-oxazolidin-3-yl)ethyl]-3,4-dihydro-2H-1,4-benzothiazin-3-one

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C20H16Cl2N2O3S, is built up from a dihydrobenzothiazine moiety linked by –CH– and –C2H4– units to 2,4-dichlorophenyl and 2-oxo-1,3-oxazolidine substituents, where the oxazole ring and the heterocyclic portion of the ...
Brahim Hni, Nada Kheira Sebbar, Tuncer Hökelek, Lhoussaine El Ghayati, Younes Bouzian, Joel T. Mague, El Mokhtar Essassi   +6 more
doaj   +1 more source

Helium nanodroplet infrared spectroscopy of oxazole-(water)n (n = 1,2) clusters

AIP Advances, 2021
The mass-selective infrared (IR) spectra of oxazole-(D2O)n≤2 complexes embedded in helium droplets are recorded in the spectral range of 2565–2800 cm−1. The experimental IR spectra are assigned by comparing with quantum chemical calculations at the MP2/6-
Tarun Kumar Roy, Kuntal Chatterjee, Jai Khatri, Gerhard Schwaab, Martina Havenith   +4 more
doaj   +1 more source

Isomerization of 5-(2H-Azirin-2-yl)oxazoles: An Atom-Economic Approach to 4H-Pyrrolo[2,3-d]oxazoles

Molecules, 2021
An atom economical method for the preparation of variously substituted 4H-pyrrolo[2,3-d]oxazoles was developed on the basis of thermal isomerization of 5-(2H-azirin-2-yl)oxazoles.
Timur O. Zanakhov, Ekaterina E. Galenko, Mariya A. Kryukova, Mikhail S. Novikov, Alexander A. Khlebnikov   +4 more
doaj   +1 more source

1,3-Oxazol-4-ylphosphonium salts as new non-peptide inhibitors of furin [PDF]

The Ukrainian Biochemical Journal, 2019
A series of novel triphenylphosphonium derivatives of 1,3-oxazole containing at C2 and C5-positions electron withdrawing or electron-donating groups were synthesized and characterized by 1H, 31P NMR and IR spectroscopy, element analysis and chromato-mass
T. V. Osadchuk, V. K. Kibirev1,2,, O. V. Shybyryn, A. V. Semyroz, Ye. S. Velihina, Е. R. Abdurakhmanova, V. S. Brovarets   +6 more
doaj   +1 more source

Unified Synthesis of Unconventional α‐Polyhalogenated Amines Through Hydroaminoalkylation

Angewandte Chemie International Edition, EarlyView.
A unified, redox‐neutral method that transforms alkenes and alkynes into α‐polyhalomethyl amines using stable hemiaminal reagents is reported. This approach enables access to CF3, CF2H, CF2Cl, and CFClH motifs, expanding halogenated amine space with broad substrate scope, functional group tolerance, and applicability to late‐stage modification of drug ...
Angela K. Hofmeister, Giulia Iannelli, Péter Angyal, Augustin Malandain, Daniel Kaiser, Boris Maryasin, Hanspeter Kählig, Matteo Barel, Gaia Novarino, Nuno Maulide   +9 more
wiley   +1 more source

Synthesis and Antibacterial Evaluation of Novel Heterocyclic Compounds Containing a Sulfonamido Moiety

Molecules, 2013
Aiming for the synthesis of new heterocyclic compounds containing a sulfonamido moiety suitable for use as antibacterial agents, the precursor ethyl {[4-N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenylazo}cyanoacetate was reacted with a variety of active ...
Eman A. El-Bordany, Mohamed M. Youssef, Mohammad Emad Azab   +2 more
doaj   +1 more source

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

Angewandte Chemie International Edition, EarlyView.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee, Sumin Son, Jeong Yeon Yoo, Ji Hyae Lee, Meehyun Chun, Seung Bum Park   +5 more
wiley   +1 more source