Results 41 to 50 of about 7,689 (220)

The LANCA three-component reaction to highly substituted β-ketoenamides – versatile intermediates for the synthesis of functionalized pyridine, pyrimidine, oxazole and quinoxaline derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2019
The LANCA three-component reaction of lithiated alkoxyallenes LA, nitriles N and carboxylic acids CA leads to β-ketoenamides KE in good to excellent yields.
Tilman Lechel   +4 more
doaj   +1 more source

Recent Advances on O-Ethoxycarbonyl and O-Acyl Protected Cyanohydrins

open access: yesMolecules, 2021
Ethoxycarbonyl cyanohydrins and O-acyl cyanohydrins are examples of O-protected cyanohydrins in which the protecting group presents an electrophilic center, contributing to additional reaction pathways.
Héctor Manuel Torres Domínguez   +2 more
doaj   +1 more source

Oxazole and thiazole analogs of sulindac for cancer prevention [PDF]

open access: yes, 2018
Aim: Experimental and epidemiological studies and clinical trials suggest that nonsteroidal anti-inflammatory drugs possess antitumor potential. Sulindac, a widely used nonsteroidal anti-inflammatory drug, can prevent adenomatous colorectal polyps and ...
Connelly, Michele C.   +4 more
core   +2 more sources

Diradicalar Character and Ring Stability of Mesoionic Heterocyclic Oxazoles and Thiazoles by Ab Initio Mono and Multi-Reference Methods

open access: yesMolecules, 2020
Mesoionics are neutral compounds that cannot be represented by a fully covalent or purely ionic structure. Among the possible mesomeric structures of these compounds are the diradical electronic configurations.
Antonio João da Silva Filho   +2 more
doaj   +1 more source

Modular Generation of Alkyl Selenyl Radicals for the Synthesis of Alkyl Selenides via a Mechanochemical Approach

open access: yesAdvanced Science, EarlyView.
We present a mechanochemical, radical‐mediated hydroselenation of alkenes under ambient conditions. This method modularly generates alkyl selenyl radicals from elemental selenium and alkyl (pseudo)halides, utilizing PhSiH3 and H2O as hydrogen atom donors, with the water likely originating from the air and/or trace water present in the reagents ...
Xiaochun He   +8 more
wiley   +1 more source

Componentes voláteis do café torrado. Parte I: compostos heterocíclicos Volatile components in roasted coffee. Part I: heterocyclic compounds

open access: yesQuímica Nova, 1999
A review of heterocyclic compounds in roasted coffee is presented. The contents, precursors and sensorial properties of furans, pyrroles, oxazoles, thiazoles, thiophenes, pyrazines and pyridines are discussed.
Carlos Alberto Bastos De Maria   +2 more
doaj   +1 more source

In Silico and In Vitro Assessment of Antimicrobial and Antibiofilm Activity of Some 1,3-Oxazole-Based Compounds and Their Isosteric Analogues

open access: yesApplied Sciences, 2022
In this paper, we report on the antimicrobial activity assessment of 49 compounds previously synthesized as derivatives of alanine or phenylalanine that incorporate a 4-(4-X-phenylsulfonyl)phenyl fragment (X = H, Cl, or Br), namely 21 acyclic compounds ...
Theodora-Venera Apostol   +8 more
doaj   +1 more source

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]

open access: yes, 2019
Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina   +3 more
core  

Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD [PDF]

open access: yes, 2016
Acknowledgements We thank Diamond Light Source for providing access to beamline I23. We also thank Thomas Sorensen and his staff for access to and support on beamline I02.
Bent, Andrew F   +8 more
core   +1 more source

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