Results 61 to 70 of about 5,322 (210)

SYNTHESIS OF 2,5-DISUBSTITUTED OXAZOLES FROM ALDEHYDES AND N-(TOSYLMETHYL)IMINO SYNTHONS - APPLICATION TO THE SYNTHESIS OF PIMPRININE ANALOGS

, 1981
A series of N‐(tosylmethyl)imino compounds [TosCH2N=C(L)A] has been applied to a new base‐induced, one‐operational synthesis of 2,5‐disubstituted oxazoles from aromatic aldehydes.
Houwing, Hendrik A., WILDEMAN, J, van Leusen, A.M., van Leusen, Albert M., Wildeman, Jurjen, HOUWING, HA   +5 more
core   +1 more source

Polarizability in Substituted Oxazoles: A PC-Model Data Analysis

E-Journal of Chemistry, 2005
A systematic investigation of various Oxazole derivatives has been subjected to a Polarized Continuums Model (PCM) for evaluation of their physico-chemical parameters.
S. Harikrishna, S. P. Shrivastava, J. T. Rao, S. N. Limaye   +3 more
doaj   +1 more source

A NEW SCAFFOLD FOR D3 DOPAMINERGIC AFFINITY CONTAINING ARYLPIPERAZINE FRAGMENT: MOLECULAR MODELING, SYNTHESIS, IN VITRO AND IN VIVO PHARMACOLOGICAL EVALUATION [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2007
A new series of N-(6-substitutedbenzo[d]thiazol-2-yl)-2-(4-arylpiperazin-1-yl) acetamides (3a-f) and 2-(3-(4-arylpiprazin-1-yl)propylthio)benzo[d]thiazoles/-oxazoles/-imidazole (6a-f) wassynthesized by connecting arylpiperazine through a semi-rigid ...
Franziska U. Müller, Dalal Abou El Ella   +1 more
doaj   +1 more source

TBHP/I₂-Mediated Domino Oxidative Cyclization for One-Pot Synthesis of Polysubstituted Oxazoles

, 2016
A facile type of one-pot, transition-metal-free domino process was developed for the synthesis of oxazoles. Thus, a variety of polysubstituted oxazoles were easily synthesized via t-BuOOH/I2-mediated domino oxidative cyclization from readily available ...
Huawen Huang (1427662), Chaorong Qi (1392922), Hua Cao (123075), Huanfeng Jiang (1392913)   +3 more
core   +1 more source

Azirinium ylides from α-diazoketones and 2H-azirines on the route to 2H-1,4-oxazines: three-membered ring opening vs 1,5-cyclization

Beilstein Journal of Organic Chemistry, 2015
Strained azirinium ylides derived from 2H-azirines and α-diazoketones under Rh(II)-catalysis can undergo either irreversible ring opening across the N–C2 bond to 2-azabuta-1,3-dienes that further cyclize to 2H-1,4-oxazines or reversibly undergo a 1,5 ...
Nikolai V. Rostovskii, Mikhail S. Novikov, Alexander F. Khlebnikov, Galina L. Starova, Margarita S. Avdontseva   +4 more
doaj   +1 more source

Recent Advances in Chemosensors Bearing Pyrazole and Imidazole Rings: An Approach Toward the Detection of Metal Ions Based on these Diazoles

Advanced Sensor Research, Volume 5, Issue 10, October 2026.
This contribution analyzes recent articles (2021–2025) on chemosensors containing pyrazole and imidazole rings for detecting metal ions, using distinctive examples. It focuses on the structural design of probes, their coordination behavior, sensing mechanisms, and analytical performance, including selectivity, sensitivity, working wavelength, and ...
Alexander Ladino‐Bejarano, Carlos Cifuentes, Néstor Bravo, Jaime Portilla   +3 more
wiley   +1 more source

Microhydration Structures of Protonated Oxazole [PDF]

The Journal of Physical Chemistry A, 2019
The initial microhydration structures of the protonated pharmaceutical building block oxazole (Ox), H+Ox-Wn≤4, are determined by infrared photodissociation (IRPD) spectroscopy combined with quantum chemical dispersion-corrected density functional theory calculations (B3LYP-D3/aug-cc-pVTZ).
Kuntal Chatterjee, Otto Dopfer
openaire   +2 more sources

Oxazoles as dienophiles in Diels-Alder reactions

, 1986
2-(N-benzyl-N-methylamino)-oxazoles undergo (4+2)-cycloadditions across the C4-C5 bond by electron deficient ...
Paola Pedrini, PEDRINI, Paola, DONDONI, Alessandro, UGOZZOLI, Franco, FOGAGNOLO, Marco, Annarosa Mastellari, A. Dondoni, F. UGOZZOLI, A. Mastellari, P. Pedrini, Marco Fogagnolo, Alessandro Dondoni, M. Fogagnolo, Franco Ugozzoli   +13 more
core   +1 more source

Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles

Molecules, 2013
Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj   +1 more source

Synthesis of Methylisoxazol‐5(4H)‐One Derivatives Using an ʟ‐Proline‐Functionalized‐MMT Catalyst: Molecular Docking and Cancer Cell Line Cytotoxicity Studies

ChemistrySelect, Volume 11, Issue 38, 13 October 2026.
An efficient and sustainable method for the synthesis of biologically relevant isoxazoles is developed using modified montmorillonite‐K10 (MMT) nanoclay as a heterogeneous catalyst. The catalyst exhibited good stability and reusability over five cycles, with minimal loss of activity (95%–88%). ABSTRACT Guided by green chemistry principles, an efficient
Anushka Servesh, Santhosh Govindaraju, Sumaiya Tabassum, Sankar Ganesh Ramaraj   +3 more
wiley   +1 more source