Results 61 to 70 of about 5,187 (206)
2,5-DIHYDRO-4-HYDROXYMETHYL-1,3-OXAZOLES BY ASINGER CONDENSATION
In this article* a simple Asinger type one-pot synthesis of 2,5-dihydro-4-hydroxymethyl-1,3-oxazoles is described in six examples.
BAYLER, A, Ugi, I., Dömling, Alex
core +1 more source
Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj +1 more source
Nickel-Catalyzed Synthesis of Oxazoles via C−S Activation
The synthesis of 2-substituted oxazoles is achieved via nickel-catalyzed cross-coupling reaction of 2-methylthio-oxazole and various organozinc reagents.
Kyoungsoo Lee (2385946) +2 more
core +1 more source
Machine Learning for Synthetic Organic Chemistry: Methods, Applications, and Best Practices
Artificial intelligence (AI) and machine learning (ML) are increasingly reshaping experimental chemistry. This review maps the challenges of synthetic organic chemistry to modern digital tools that can help address them. While focusing on the practical application of ML tools in real‐world laboratory settings, we outline prerequisites, emerging ...
Niklas Hölter +3 more
wiley +1 more source
Synthesis of Functionalized Oxazoles Via Silver Catalyzed Cyclization of Propargylamides and ...
易如霞, 吴凡, 万伯顺, 呼延成
core
Synthesis of some Heterocyclic Compounds Derived from
The 4-(?-bromo acetyl)-4?-toluene sulfonanilide (2) was used as key intermediate to synthesize new heterocyclic compounds. This bromo compound was synthesized via sulfonation of amino group of p-amino acetophenone using Hinsburg method with 4-toluene ...
Baghdad Science Journal
doaj +1 more source
Heterocyclic‐Based Fungicides: Emerging Strategies for Viable Plant Disease Control
Heterocyclic compounds have attracted considerable attention because of their structural diversity, potent antifungal activity, and ability to interact with multiple fungal targets, offering broad‐spectrum protection against phytopathogens. Synthetic and semisynthetic/part‐natural scaffolds, particularly azole, quinoline, indole, cyclotryptamine, and ...
Sumit Tahlan +4 more
wiley +1 more source
Evaluation of In Vitro Anti-inflammatory Activity of Azomethines of Aryl Oxazoles
Ability to inhibit erythrocyte hemolysis is often used as a characteristic of the membrane stabilising action of chemical compounds. Azomethines of aryl oxazoles were evaluated for anti-inflammatory by in vitro hemolytic membrane stabilising study.
V. Niraimathi, A. Jerad Suresh, T. Latha
doaj +1 more source
New heterocycles having double characters; as antimicrobial and surface active agents.
Fatty acids isothiocyanate (1) was used as a starting material to synthesize some important heterocycles such as triazoles, oxazoles, thiazoles, benzoxazoles and quinazolines by treating with different types of nucleophiles such as nitrogen nucleophiles,
M. S. Amine +4 more
doaj +1 more source
We report a novel cysteine‐to‐serine surface‐mutation approach to determine co‐crystal structures of KAT6A with small‐molecule inhibitors and compare it with the previously published MYSTcryst approach which uses mutated KAT8 as a surrogate for KAT6A.
Vera Puetter +8 more
wiley +1 more source

