Results 51 to 60 of about 5,187 (206)
European Journal of Organic Chemistry, EarlyView.Diarylethene‐containing cyclic tubulysin analogues were designed, synthesized, and evaluated as light‐responsive cytotoxic agents. One analogue showed reversible photoswitching, photoregulated tubulin polymerization inhibition, and photoform‐dependent cytotoxicity.
Anna Iampolska +9 more
wiley +1 more source
Recent advances and prospects for high‐efficiency blue hot exciton organic light‐emitting diodes
FlexMat, EarlyView.Blue organic light‐emitting diodes (OLEDs) face great challenges in achieving the balance between color purity, device efficiency, and stability. Hot exciton materials offer a solution by rapidly converting non‐emissive triplet excitons into singlet ones through a high‐lying reverse intersystem crossing process.
Xiaoen Shi +3 more
wiley +1 more source
Unified Synthesis of Unconventional α‐Polyhalogenated Amines Through Hydroaminoalkylation
Angewandte Chemie International Edition, Volume 65, Issue 38, 14 September 2026.A unified, redox‐neutral method that transforms alkenes and alkynes into α‐polyhalomethyl amines using stable hemiaminal reagents is reported. This approach enables access to CF3, CF2H, CF2Cl, and CFClH motifs, expanding halogenated amine space with broad substrate scope, functional group tolerance, and applicability to late‐stage modification of drug ...
Angela K. Hofmeister +9 more
wiley +1 more source
Polarizability in Substituted Oxazoles: A PC-Model Data Analysis
E-Journal of Chemistry, 2005 A systematic investigation of various Oxazole derivatives has been subjected to a Polarized Continuums Model (PCM) for evaluation of their physico-chemical parameters.
S. Harikrishna +3 more
doaj +1 more source
A NEW SCAFFOLD FOR D3 DOPAMINERGIC AFFINITY CONTAINING ARYLPIPERAZINE FRAGMENT: MOLECULAR MODELING, SYNTHESIS, IN VITRO AND IN VIVO PHARMACOLOGICAL EVALUATION [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2007 A new series of N-(6-substitutedbenzo[d]thiazol-2-yl)-2-(4-arylpiperazin-1-yl) acetamides (3a-f) and 2-(3-(4-arylpiprazin-1-yl)propylthio)benzo[d]thiazoles/-oxazoles/-imidazole (6a-f) wassynthesized by connecting arylpiperazine through a semi-rigid ...
Franziska U. Müller +1 more
doaj +1 more source
Recent Applications of Propylene Carbonate as a Solvent in Sustainable Organic Synthesis
ChemSusChem, Volume 19, Issue 17, 14 September 2026.This review evaluates propylene carbonate (PC) as a non‐toxic green solvent in organic synthesis, highlighting its performance in key reactions including cross‐couplings, asymmetric hydrogenations, peptide synthesis and biocatalysis. Across these processes, PC delivers yields comparable to conventional and alternative green solvents.
Laura G. Aguilar‐Sanchez +1 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2015 Strained azirinium ylides derived from 2H-azirines and α-diazoketones under Rh(II)-catalysis can undergo either irreversible ring opening across the N–C2 bond to 2-azabuta-1,3-dienes that further cyclize to 2H-1,4-oxazines or reversibly undergo a 1,5 ...
Nikolai V. Rostovskii +4 more
doaj +1 more source
Truncation of Samroiyotmycin: Tailored seco‐Acids as Novel Antimalaria Compounds
European Journal of Organic Chemistry, Volume 29, Issue 34, 11 September 2026.Six truncated samroiyotmycin‐derived antimalarials were synthesized by replacing the tosyloxazole unit with electron‐deficient aryl groups. The most active seco‐acid with EWG = 2 × CF3 outperformed the natural product SamA. Its enhanced activity supports a donor–acceptor interaction involving the electron‐poor aryl unit, consistent with inhibition of ...
Anton Czuczkowski +10 more
wiley +1 more source
Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation
Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco +5 more
wiley +1 more source
Isocyano Enones: Addition–Cyclization Cascade to Oxazoles
, 2016 Copper iodide catalyzes the conjugate addition of organometallic and heteroatom nucleophiles to isocyano enones to afford oxazoles. A range of enolates, metalated nitriles, amines, and thiols undergo catalyzed conjugate addition to cyclic and acyclic ...
Fraser F. Fleming (1520524) +2 more
core +1 more source