Results 71 to 80 of about 7,689 (220)

Polarizability in Substituted Oxazoles: A PC-Model Data Analysis

E-Journal of Chemistry, 2005
A systematic investigation of various Oxazole derivatives has been subjected to a Polarized Continuums Model (PCM) for evaluation of their physico-chemical parameters.
S. Harikrishna, S. P. Shrivastava, J. T. Rao, S. N. Limaye   +3 more
doaj   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source

Azirinium ylides from α-diazoketones and 2H-azirines on the route to 2H-1,4-oxazines: three-membered ring opening vs 1,5-cyclization

Beilstein Journal of Organic Chemistry, 2015
Strained azirinium ylides derived from 2H-azirines and α-diazoketones under Rh(II)-catalysis can undergo either irreversible ring opening across the N–C2 bond to 2-azabuta-1,3-dienes that further cyclize to 2H-1,4-oxazines or reversibly undergo a 1,5 ...
Nikolai V. Rostovskii, Mikhail S. Novikov, Alexander F. Khlebnikov, Galina L. Starova, Margarita S. Avdontseva   +4 more
doaj   +1 more source

Synthesis of new beta-amidodehydroaminobutyric acid derivatives and of new tyrosine derivatives using copper catalyzed C-N and C-O coupling reactions [PDF]

, 2012
Several beta-amidodehydroaminobutyric acid derivatives were prepared from N,C-diprotected beta-bromodehydroaminobutyric acids and amides by a copper catalyzed C-N coupling reaction.
Ferreira, Paula M. T., Pereira, Goreti, Vilaça, Helena   +2 more
core   +1 more source

Molecular Mechanisms of Resistance and Treatment Efficacy of Delamanid Against Mycobacterium tuberculosis: A Systematic Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Tuberculosis (TB) remains a major global health problem, and treatment progress is increasingly threatened by rising multidrug‐resistant tuberculosis (MDR‐TB). Delamanid (DLM), a nitroimidazole drug, has shown good efficacy and safety against both drug‐susceptible and drug‐resistant Mycobacterium tuberculosis (Mtb) strains.
Md. Mahmudul Islam, Md. Zahid Hasan, Md. Touki Tahamid Tusar, Md. Yeamin Hossain, Md. Motaher Hossain, Md. Abdulla Al Jubayed, Md. Jubaer‐Al‐Abedin, Sheikh Soikot, Shanzida Akther, Jahid Bhuyian, Hafizur Rahman Gazi, B. M. Mahmudul Hasan, Md. Shofiul Azam, Md. Enamul Haque, Abdullah‐Al‐Jubayer, Md. Faruk Hasan, F. M. Ali Haydar, Md. Khalekuzzaman, Md. Torequl Islam, Sohel Hasan   +19 more
wiley   +1 more source

Total synthesis of the post-translationally modified polyazole peptide antibiotic goadsporin [PDF]

, 2017
The structurally unique polyazole antibiotic goadsporin contains six heteroaromatic oxazole and thiazole rings integrated into a linear array of amino acids that also contains two dehydroalanine residues.
Arnison, Bagley, Bredenkamp, Connell, Davies, Doyle, Doyle, El-Faham, Haginaka, Hughes, Igarashi, Kaul, Lin, Linder, Nicolaou, Onaka, Onaka, Onaka, Onaka, Ozaki, Platzer, Wada, Wipf   +22 more
core   +2 more sources

AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives

Journal of Integrative Plant Biology, Volume 68, Issue 5, Page 1384-1398, May 2026.
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li, Tao Zeng, Hongquan Xu, Xu Kang, Minghui Liang, Ruibo Wu   +5 more
wiley   +1 more source

One-Pot Synthesis of Polysubstituted Oxazoles by the Catalysis of FeCl3 under MW and Synthesis of Leaf Alcohol and 2-Deoxy-L-glucose [PDF]

, 2010
一、含噁唑环类化合物广泛存在于天然产物和药物中，其合成方法备受关注。我们成功地发展了一种快速而有效的三氯化铁催化的微波条件下由炔丙酯与酰胺合成多取代噁唑的方法（见图1）。该方法中我们用单一的三氯化铁催化剂催化了两个不同的反应，即先催化取代反应生成取代产物，中间体无需分离，再催化环化异构反应“一锅”内生成目标产物多取代噁唑，并且应用了“绿色”的热源，反应时间短，操作简便，产率较令人满意，且底物应用范围较广。因而这一方法不失为合成多取代噁唑的方法的补充 ...
续文文
core  

Iodoaminations of alkenes [PDF]

, 2016
The activation of alkenes and their subsequent functionalization is a frequently used methodology in synthetic chemistry. This review highlights recent iodine-mediated aminations and elaborates on the various strategies to bring about regio- or ...
Mizar, Pushpak, Wirth, Thomas
core   +1 more source

Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles

Molecules, 2013
Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj   +1 more source