Results 91 to 100 of about 4,839 (215)

Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles

Molecules, 2012
In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf2NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4 ...
Yuji Hanzawa, Akio Saito, Nao Hyodo
doaj   +1 more source

oxazoles

, 2014
WOS: 000330163300031Furan-3-one derivatives 1 were converted into 2-hydroxy-pyrrole-3-ones 4 by reacting with various - and -amino acids. In contrast, the reaction of furan-3-ones and 1-aminocyclobutanecarboxylic acid afforded spiro-pyrrolo[2,1-b][1,3 ...
Üngören, Sevket Hakan, Mustafa Saçmacı, Koca, İrfan, Sacmaci, Mustafa, Filiz Yılmaz, Şevket Hakan Üngören, Yilmaz, Filiz, İrfan Koca, Yılmaz, Filiz   +8 more
core   +1 more source

Synthesis of substituted oxazoles via Pd-catalyzed tandem oxidative cyclization

, 2017
An easy approach to access multisubstituted oxazoles via tandem oxidative cyclization is developed.
Wei Zhang, Yuhong Zhang, Zhanxiang Liu, Wenlong Yu, Qiangqiang Yan   +4 more
core   +1 more source

MW-Assisted Synthesis of Eight New 6-Nitrilmethyl Pyrrolo[3,4-b]pyridin-5-Ones via a Domino Process: aza Diels–Alder/N-Acylation/Aromatization

Proceedings, 2019
An efficient Microwave (MW)-assisted synthesis of eight new 6-nitrilmethyl-pyrrolo[3,4-b]pyridin-5-ones via a domino process: aza Diels–Alder/N-acylation/aromatization (dehydration–decarboxylation) from their corresponding 2-aminonitrile ...
Manuel A. Rentería-Gómez, Shrikant G. Pharande, Alejandro Islas-Jácome, Eduardo González-Zamora, Rocío Gámez-Montaño   +4 more
doaj   +1 more source

Identification of Volatile Compounds and Selection of Discriminant Markers for Elephant Dung Coffee Using Static Headspace Gas Chromatography—Mass Spectrometry and Chemometrics

Molecules, 2018
Elephant dung coffee (Black Ivory Coffee) is a unique Thai coffee produced from Arabica coffee cherries consumed by Asian elephants and collected from their feces.
Poowadol Thammarat, Chadin Kulsing, Kanet Wongravee, Natchanun Leepipatpiboon, Thumnoon Nhujak   +4 more
doaj   +1 more source

TBHP/I₂-Mediated Domino Oxidative Cyclization for One-Pot Synthesis of Polysubstituted Oxazoles

, 2016
A facile type of one-pot, transition-metal-free domino process was developed for the synthesis of oxazoles. Thus, a variety of polysubstituted oxazoles were easily synthesized via t-BuOOH/I2-mediated domino oxidative cyclization from readily available ...
Huawen Huang (1427662), Chaorong Qi (1392922), Hua Cao (123075), Huanfeng Jiang (1392913)   +3 more
core   +1 more source

A Convenient Oxazole C-2 Protecting Group:  The Synthesis of 4- and 5-Substituted Oxazoles via Metalation of 2-Triisopropylsilyloxazoles

, 2016
Metalation of oxazoles at the 4 and 5 position was achieved after regioselective C-2 silyl protection. Removal of the protecting group was then accomplished under mild conditions allowing for a straightforward preparation of C-5 monosubstituted and C-4,5
Benjamin Marcune (1508755), Ross A. Miller (2666266), Randi M. Smith (2666263)   +2 more
core   +2 more sources

A Practical Approach to the Synthesis of 2,4-Disubstituted Oxazoles from Amino Acids

, 2016
A new sequence for the synthesis of various 2,4-disubstituted oxazoles from α-amino acids is reported. The method is shown to be general and incorporates the reagent combination, triphenylphosphine/hexachloroethane, for cyclodehydration of intermediate α-
Molly DeTuri (2640031), Scot Campbell (1968172), Tina Morwick (2322700), Matt Hrapchak (2640043)   +3 more
core   +1 more source

Aromaticities of Five Membered Heterocycles through Dimethyldihydropyrenes Probe by Magnetic and Geometric Criteria

Journal of Chemistry, 2015
Aromaticities of five membered heterocycles, containing up to three heteroatoms, are quantified through the dimethyldihydropyrene (DHP) probe. Bond fixation caused by the fusion of heterocycles to the dimethyldihydropyrene nucleus (DHPN) was measured by ...
Maria, Khurshid Ayub
doaj   +1 more source

Reactions between Weinreb Amides and 2-Magnesiated Oxazoles:  A Simple and Efficient Preparation of 2-Acyl Oxazoles

, 2016
Treatment of oxazole or 5-aryl oxazoles with i-PrMgCl smoothly generates the corresponding 2-Grignard reagents, which react with Weinreb amides to provide exclusively 2-acyl oxazole ...
Christopher M. Mapes (2250142), Daniel J. Pippel (1562482), Neelakandha S. Mani (1393090)   +2 more
core   +1 more source