Results 101 to 110 of about 7,689 (220)

Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

Molecules, 2018
The 8-hydroxyquinoline pharmacophore scaffold has been shown to possess a range of activities as metal chelation, enzyme inhibition, cytotoxicity, and cytoprotection.
Iván Kanizsai, Ramóna Madácsi, László Hackler Jr., Márió Gyuris, Gábor J. Szebeni, Orsolya Huzián, László G. Puskás   +6 more
doaj   +1 more source

Aromaticities of Five Membered Heterocycles through Dimethyldihydropyrenes Probe by Magnetic and Geometric Criteria

Journal of Chemistry, 2015
Aromaticities of five membered heterocycles, containing up to three heteroatoms, are quantified through the dimethyldihydropyrene (DHP) probe. Bond fixation caused by the fusion of heterocycles to the dimethyldihydropyrene nucleus (DHPN) was measured by ...
Maria, Khurshid Ayub
doaj   +1 more source

Synthesis and biological evaluation of 4-(1H-imidazol-2-yl)-2-(pyrimidin-5-yl)oxazoles as potent anticancer agents

Results in Chemistry
A new series of aryl derivatives of 4-(1H-imidazol-2-yl)-2-(pyrimidin-5-yl)oxazoles 11a–j were synthesised and their structures were characterized by analytical techniques.
Divya Komirishetti, Vasantha Mittapelli
doaj   +1 more source

Targeting the Hsp90 interactome using in silico polypharmacology approaches [PDF]

, 2013
In recent years, polypharmacology has gained popularity in drug discovery. [1] Especially for complex diseases such as cancer, the ability of a drug to bind to and interfere with multiple targets provides new opportunities for therapeutic intervention ...
Anighoro, Andrew, Bajorath, J., Heikamp, K., Rastelli, Giulio, Stumpfe, D.   +4 more
core  

Synthesis and biological evaluation of chalcone derivatives of oxazole-pyrimidines as anticancer agents

Results in Chemistry
We have developed a new library of chalcone derivatives of oxazole-pyrimidines (16a-j) and their structures were confirmed by analytical data. Further, in vitro anticancer activity of the newly prepared compounds 16a-j was assessed against a panel of ...
Divya Komirishetti, Tasqeeruddin Syed, Vasantha Mittapelli   +2 more
doaj   +1 more source

Flavouring Group Evaluation 85: Consideration of miscellaneous nitrogen‐containing substances evaluated by JECFA (65th meeting) ‐ Scientific Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food

EFSA Journal, 2008
European Food Safety Authority (EFSA)
doaj   +1 more source

NH-1,2,3-triazoles as versatile building blocks in denitrogenative transformations. [PDF]

RSC Adv, 2023
Motornov V, Beier P.
europepmc   +1 more source

Silver(i)-mediated oxazoline formation: a mild route to 2,4-oxazoles in peptides. [PDF]

Chem Sci
Pickett AS, Campbell JW, Cox KM, Bello ZA, Johnson ER, Charron CL.   +5 more
europepmc   +1 more source

Asymmetric Electrophilic alpha-Amidoalkylation 6 [PDF]

, 1989
Praschak, Ilona, Wanner, Klaus Th.
core   +1 more source

Synthetic Strategies to Access Fluorinated Azoles. [PDF]

European J Org Chem
El-Gaber MKA, Djugovski M, Huang TY, Adhikari S, Roy S.   +4 more
europepmc   +1 more source