Results 11 to 20 of about 546 (157)
Prolonged tedizolid use in cutaneous non-tuberculous mycobacterial infection
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2021 Cutaneous non-tuberculous mycobacterial (NTM) infections are an emerging infectious disease and require a protracted course of combination antibiotics. Antimicrobial choice is limited by resistance and toxicity.
Timothy David Shaw +3 more
doaj +2 more sources
Brazilian Journal of Infectious Diseases, 2016 Acute bacterial skin and skin structure infections are caused mainly by Gram-positive bacteria which are often treated with intravenous vancomycin, daptomycin, or linezolid, with potential step down to oral linezolid for outpatients.
Alejandro Ortiz-Covarrubias +9 more
doaj +2 more sources
Pharmacokinetic/Pharmacodynamic Analysis of Tedizolid Phosphate Compared to Linezolid for the Treatment of Infections Caused by Gram-Positive Bacteria [PDF]
Antibiotics, 2021 Tedizolid and linezolid have antibacterial activity against the most important acute bacterial skin and skin-structure infection (ABSSSIs) pathogens.
Alicia Rodríguez-Gascón +3 more
doaj +2 more sources
Potential role of tedizolid phosphate in the treatment of acute bacterial skin infections
Drug Design, Development and Therapy, 2013 Olatz Urbina,1 Olivia Ferrández,1 Mercè Espona,1 Esther Salas,1 Irene Ferrández,2 Santiago Grau1 1Services of Hospital Pharmacy, Hospital Universitari del Mar, Universitat Autònoma de Barcelona, 2Ciència i Tecnologia ...
Urbina O +5 more
doaj +4 more sources
Effect of the human endotoxin challenge on tedizolid tissue penetration
British Journal of Clinical Pharmacology, 2022 The effects of the human endotoxin challenge on tissue pharmacokinetics are unknown. In the present study, we aimed to assess the effect of the endotoxin challenge on interstitial fluid pharmacokinetics of tedizolid in healthy volunteers using intramuscular microdialysis. Eight healthy male subjects were treated with 200 mg of tedizolid phosphate for 6
Anselm Jorda +10 more
openaire +3 more sources
In vitro activity of tedizolid against 43 species of Nocardia species
Scientific ReportsThe purpose of the present study was to evaluate the in vitro activity of tedizolid against several clinically significant species of Nocardia by comparing with that of linezolid.
Masahiro Toyokawa +9 more
doaj +2 more sources
Long-Term Use of Tedizolid in Osteoarticular Infections: Benefits among Oxazolidinone Drugs [PDF]
Antibiotics, 2021 Background: To evaluate the efficacy and safety of long-term use of tedizolid in osteoarticular infections. Methods: Multicentric retrospective study (January 2017–March 2019) of osteoarticular infection cases treated with tedizolid.
Eva Benavent +9 more
doaj +2 more sources
In Vitro Activity of Tedizolid against Mycobacterium tuberculosis [PDF]
Antimicrobial Agents and Chemotherapy, 2019 Tedizolid is a novel oxazolidinone with activities against Gram-positive microorganisms, including mycobacteria. We studied the in vitro activity of tedizolid against 120 Mycobacterium tuberculosis strains, including susceptible, first-line-resistant, and multidrug-resistant isolates.
Ruiz Martínez, P. +3 more
openaire +7 more sources
Journal of Global Antimicrobial Resistance, 2022 Objectives: The aim of this study is to compare the in vitro activity and minimal inhibitory concentration (MIC) distributions of tedizolid and linezolid against Mycobacterium avium complex (MAC) strains using a reference broth microdilution assay and a ...
Eduardo Marfil +3 more
doaj +2 more sources
Infection and Drug Resistance, 2015 Ronald G Hall 2nd, Heidi N Michaels Texas Tech University Health Sciences Center, Dallas, TX, USA Abstract: Tedizolid phosphate is the first once-daily oxazolidinone approved by the United States Food and Drug Administration for the treatment of acute ...
Hall RG 2nd, Michaels HN
doaj +1 more source