Emerging Treatment Options for Acute Bacterial Skin and Skin Structure Infections and Bloodstream Infections Caused by Staphylococcus aureus: A Comprehensive Review of the Evidence. [PDF]
: Staphylococcus aureus remains an important human pathogen of concern, with mortality rates surpassing 30% in the case of severe systemic infections. Distinguishing methicillin-susceptible S. aureus from methicillin-resistant S.
Giacobbe DR +7 more
europepmc +2 more sources
Tedizolid and linezolid have antibacterial activity against the most important acute bacterial skin and skin-structure infection (ABSSSIs) pathogens.
Alicia Rodríguez-Gascón +3 more
doaj +1 more source
Oritavancin for acute bacterial skin and skin structure infections [PDF]
Inpatient treatment of acute bacterial skin and skin structure infections (ABSSSIs) exerts a significant economic burden on the healthcare system. Oritavancin is a concentration-dependent, rapid bactericidal agent approved for the treatment of ABSSSIs.
Julia A, Messina +2 more
openaire +2 more sources
Assessment of pharmacokinetics-pharmacodynamics to support omadacycline dosing regimens for the treatment of patients with acute bacterial skin and skin structure infections. [PDF]
Michael Trang, Christopher Rubino
exaly +2 more sources
Dalbavancin for the treatment of acute bacterial skin and skin structure infections [PDF]
Acute bacterial skin and skin structure infections (ABSSSI) have increased in incidence and severity. The involvement of resistant organisms, particularly methicillin-resistant Staphylococcus aureus, presents additional challenges. The lipoglycopeptide dalbavancin has a prolonged half-life, high protein binding, and excellent tissue levels which led to
Sheena, Ramdeen, Helen W, Boucher
openaire +2 more sources
Multidisciplinary panel opinion on the management of bacterial skin infections
Eight hot topics regarding the diagnosis and management of bacterial skin infections were selected and reviewed by five experts from different European countries, chosen based on their expertise in microbiology, infectious diseases, and dermatology.
Emilio Bouza +4 more
doaj +1 more source
Dalbavancin for the treatment of acute bacterial skin and skin structure infections (ABSSSI) in pediatric patients: a case series. [PDF]
Acute bacterial skin and skin-structure infections (ABSSSI) are a significant cause of morbidity in pediatric patients, requiring timely and effective treatment.
Garbo V +7 more
europepmc +2 more sources
Acute bacterial skin and skin-structure infections (ABSSSI) is defined in 2013 by the US Food and Drug Administration as a bacterial cellulitis/erysipelas, major skin abscesses, and wound infections.
Erni Juwita Nelwan +3 more
doaj +2 more sources
Introduction The prevalence of acute bacterial skin and skin structure infections (ABSSSIs) continues to increase. Bloodstream infection (BSI) is a severe secondary complication of ABSSSI.
Michael J. Rybak +6 more
doaj +1 more source
Antimicrobial Peptides and Skin: A Paradigm of Translational Medicine [PDF]
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Schöllmann, C. +3 more
core +1 more source

