Results 61 to 70 of about 52,424 (257)

Tedizolid: A comprehensive review of pharmacology, clinical applications and future directions in antimicrobial resistance [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases
Tedizolid phosphate, a second-generation xazolidinone, has emerged as a valuable tool in the treatment of Gram-positive bacterial infections, particularly those caused by multidrug-resistant organisms such as methicillin-resistant Staphylococcus aureus ...
Shambo Samajdar, Rupak Chatterjee, Shatavisa Mukherjee, Manoranjan Behera, Shravan Venkatraman, Jyotirmoy Pal, Nandini Chatterjee, Shashank Joshi   +7 more
doaj   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

New developments in the treatment of acute bacterial skin and skin structure infections: considerations for the effective use of dalbavancin

Therapeutics and Clinical Risk Management, 2016
Janelle J Juul, Caitlin F Mullins, William J Peppard, Angela M Huang Department of Pharmacy, Froedtert & the Medical College of Wisconsin, Milwaukee, WI, USA Abstract: Dalbavancin, an intravenous glycopeptide, was approved by the US Food and Drug ...
Juul JJ, Mullins CF, Peppard WJ, Huang AM   +3 more
doaj  

Updated Review on Clinically-Relevant Properties of Delafloxacin

Antibiotics, 2023
The extensive use of fluoroquinolones has been consequently accompanied by the emergence of bacterial resistance, which triggers the necessity to discover new compounds.
Adrien Turban, François Guérin, Aurélien Dinh, Vincent Cattoir   +3 more
doaj   +1 more source

Rare‐Earth–Functionalized Carbon Dot Hydrogels as Mechanically Robust Antibacterial Wound Dressings

Advanced Healthcare Materials, EarlyView.
The schematic depicts a dynamically cross‐linked PVA hydrogel network in which reversible borate ester bonds and hydrogen‐bonding interactions integrate lanthanum‐doped carbon dots (La‐CDs) and dipotassium glycyrrhizinate (DPG) to form a mechanically robust, multifunctional matrix.
Shih‐Han Tsai, Ramadhass Keerthika Devi, Muthusankar Ganesan, Guo‐Ping Chang Chien, Chun Che Lin   +4 more
wiley   +1 more source

Potential for Cost Saving with Iclaprim Owing to Avoidance of Vancomycin-Associated Acute Kidney Injury in Hospitalized Patients with Acute Bacterial Skin and Skin Structure Infections.

, 2018
Click on the Resource Link to access the article (may not be free).BACKGROUND AND OBJECTIVE: Vancomycin is the most prescribed antibiotic for hospitalized adults with skin and skin structure infections.
Patel, Nimish, Lodise, Thomas P, Huang, David B   +2 more
core   +1 more source

A preliminary investigation into the risk factors associated with cellulitis of the lower limb

, 2009
Cellulitis is an infective/inflammatory skin condition costing 426,000 bed days per year. The legs are most frequently affected and 18-20% of patients suffer from recurrent attacks.
Collins, Carol
core   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

New antibiotics for skin and skin-structure infections

, 2014
Comment on Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): a randomised, double-blind, phase 3, non-inferiority trial.
Tacconelli, Evelina, Kern, Winfried V., Kern, Winfried V   +2 more
core   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source