Results 31 to 40 of about 175,069 (252)
With the development of global warming, extreme high-temperature weather events have frequently occurred. Elevated water temperature can promote lipid deposition in the liver of fish and then cause fish death, ultimately leading to considerable economic ...
Yue Ru +11 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Acute Liver Injury and Acute Liver Failure following Bariatric Surgery
Bariatric surgery is the most effective treatment for obesity and improves several manifestations of the metabolic syndrome, including nonalcoholic fatty liver disease.
Rowan F. van Golen +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Background Portal vein embolization is essential for patients with biliary cancer who undergo extended hepatectomy to induce hypertrophy of the future remnant liver.
Chun-Yi Tsai +5 more
doaj +1 more source
Oxidative Stress in Liver Pathophysiology and Disease
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which not only arise during metabolic functions but also during the biotransformation of xenobiotics.
Abdolamir Allameh +4 more
doaj +1 more source
Idiopathic acute fatty liver of pregnancy [PDF]
A maternal survivor of idiopathic fatty liver, with the characteristic histological appearance on liver biopsy, is reported. Profound hypoglycaemia was the major complication in this patient and it is suggested that more attention should be given to the blood glucose in this disease. The consideration of future pregnancy in this patient is discussed.
K J, Breen +3 more
openaire +2 more sources
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Background & Aims: The steatotic grafts have been applied in liver transplantation frequently owing to the high incidence of non-alcoholic fatty liver disease. However, fatty livers are vulnerable to graft injury.
Hui Liu +13 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

