Acute flaccid myelitis (AFM) is an incompletely understood neurologic disorder occurring in epidemic fashion causing weakness ranging from mild paresis to devastating paralysis in children and some adults. This article reviews the case definition of AFM as well as its epidemiology and association with enteroviral infection.
William, Ide +2 more
exaly +5 more sources
Enterovirus D68: Genomic and Clinical Comparison of 2 Seasons of Increased Viral Circulation and Discrepant Incidence of Acute Flaccid Myelitis-Maryland, USA. [PDF]
Background Enterovirus D68 (EV-D68) is associated with severe respiratory disease and acute flaccid myelitis (AFM). The 2022 outbreaks showed increased viral circulation and hospital admissions, but the expected rise in AFM cases did not occur.
Fall A +8 more
europepmc +2 more sources
Acute Flaccid Myelitis Associated with Enterovirus D68 in Children, Argentina, 2016
After a 2014 outbreak of severe respiratory illness caused by enterovirus D68 in the United States, sporadic cases of acute flaccid myelitis have been reported worldwide.
Carolina M. Carballo +10 more
doaj +2 more sources
Acute Flaccid Myelitis Surveillance - United States, January 2020-December 2025. [PDF]
Acute flaccid myelitis (AFM) is a rare but serious neurologic condition that causes paralysis and primarily affects children. Clinically and radiologically, AFM is indistinguishable from the acute flaccid paralysis of poliomyelitis caused by poliovirus ...
Lopez AS +8 more
europepmc +2 more sources
Nerve Transfer Surgery in Acute Flaccid Myelitis: Prognostic Factors, Long-Term Outcomes, Comparison With Natural History. [PDF]
Background: Nerve transfer surgery is sometimes offered to patients with acute flaccid myelitis (AFM). The objectives of this study were to evaluate surgical efficacy, assess which clinical and neurophysiological data are valuable for preoperative ...
Rivera GS +5 more
europepmc +2 more sources
Adult Onset Acute Flaccid Myelitis: A Case Report. [PDF]
We report a 23-year-old male who presented with acute dysarthria, dysphagia, and quadriparesis. These symptoms were preceded by fever and headache. His neurological symptoms were progressive and rendered him quadriplegic over three weeks.
Peeran A +3 more
europepmc +2 more sources
Acute Flaccid Myelitis Caused by West Nile Virus: A Case Report and Neuroimaging Correlate. [PDF]
West Nile virus (WNV) is the most common mosquito-borne illness in the United States. Most cases remain asymptomatic or may be associated with a mild febrile illness; however, it can invade the central nervous system and cause meningoencephalitis, or ...
Creswell A +5 more
europepmc +2 more sources
Transcutaneous Spinal Cord Stimulation Enables Recovery of Walking in Children with Acute Flaccid Myelitis. [PDF]
Background: Limited research exists for use of transcutaneous spinal stimulation (TSS) in pediatric spinal cord injuries (SCI) to improve walking outcomes, especially in children diagnosed with SCI secondary to acute flaccid myelitis (AFM).
Neighbors E +3 more
europepmc +2 more sources
Multimodal Surveillance Model for Enterovirus D68 Respiratory Disease and Acute Flaccid Myelitis among Children in Colorado, USA, 2022. [PDF]
Surveillance for emerging pathogens is critical for developing early warning systems to guide preparedness efforts for future outbreaks of associated disease.
Messacar K +12 more
europepmc +2 more sources
Using the Acute Flaccid Paralysis Surveillance System to Identify Cases of Acute Flaccid Myelitis, Australia, 2000‒2018 [PDF]
Since 2012, the United States has reported a distinct syndrome of acute flaccid paralysis (AFP) with anterior myelitis, predominantly in children. This polio-like syndrome was termed acute flaccid myelitis (AFM).
Liz J. Walker +5 more
doaj +2 more sources

