VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. [PDF]
J VirolEnterovirus D68 (EV-D68) is an emerging pathogen that can cause severe respiratory and neurologic disease [acute flaccid myelitis (AFM)]. Intramuscular (IM) injection of neonatal Swiss Webster (SW) mice with US/IL/14-18952 (IL52), a clinical isolate from
Leser JS +5 more
europepmc +2 more sources
Midterm Outcomes of Surgical Reconstruction and Spontaneous Recovery of Upper-Extremity Paralysis Following Acute Flaccid Myelitis. [PDF]
JB JS Open AccessBackground: Acute flaccid myelitis (AFM) is a disabling, poliomyelitis-like illness that mainly affects children. Although various surgical interventions are performed for intractable paralysis due to AFM, the timing of surgery and its long-term outcomes
Doi K +5 more
europepmc +2 more sources
Response to: 'Acute flaccid myelitis in low to middle income countries: diagnosis and surveillance'. [PDF]
Brain Communacute
Olum S +4 more
europepmc +2 more sources
Scoliosis in Pediatric Patients With Acute Flaccid Myelitis. [PDF]
Top Spinal Cord Inj Rehabil, 2022 Background: Acute flaccid myelitis (AFM) is an anterior horn disorder that manifests as rapid onset muscle weakness or paralysis. Development of scoliosis in pediatric AFM patients has been anecdotally reported, but associated risk factors or incidence have yet to be determined.
Suresh KV +4 more
europepmc +3 more sources
Acute Flaccid Myelitis in COVID-19. [PDF]
BJR Case Rep, 2020 Spinal cord imaging findings in COVID-19 are evolving with the increasing frequency of neurological symptoms among COVID-19 patients. Several mechanisms are postulated to be the cause of central nervous system affection including direct virus neuroinvasive potential, post infectious secondary immunogenic hyperreaction, hypercoagulability, sepsis and ...
Abdelhady M, Elsotouhy A, Vattoth S.
europepmc +3 more sources
European Journal of Neurology, 2023 Acute flaccid myelitis (AFM) and transverse myelitis (TM) are serious conditions that may be difficult to differentiate, especially at onset of disease. In this study, we compared clinical features of pediatric AFM and TM and evaluated current diagnostic
Rinze F Neuteboom +2 more
exaly +2 more sources
Studies of C57BL/6J Mice Deficient in Receptors for IFNα/β and IFNγ as a Model for EV-D68 Acute Flaccid Myelitis [PDF]
Comp MedEnterovirus D68 (EV-D68) causes severe respiratory disease and is a strong candidate as the etiologic agent of acute flaccid myelitis. Acute flaccid myelitis is a rare neurologic disorder that typically affects adolescents less than 13 y old, manifesting
Watarastaporn T +5 more
europepmc +2 more sources
Mycoplasma pneumoniae-associated transverse myelitis presenting as asymmetric flaccid paralysis
Clinics and Practice, 2019 Acute transverse myelitis is a rare spinal cord inflammatory disorder that manifests as sudden onset of motor, sensory, and autonomic dysfunctions.
Shafee Salloum +2 more
doaj +2 more sources
Adult-onset Acute Flaccid Myelitis Accompanied by Rhombencephalitis Which First Presented with Prominent Psychiatric Symptoms and Dysautonomia Mimicking Anti-N-methyl-D-aspartate Receptor Encephalitis. [PDF]
Intern MedA 44-year-old woman with a subacute onset of an altered mental status, urinary retention, and fluctuating blood pressure was initially diagnosed with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, meeting the criteria of Graus et al.
Sumikura H +12 more
europepmc +2 more sources
Enterovirus D68–Associated Acute Flaccid Myelitis, United States, 2020 [PDF]
Emerging Infectious Diseases, 2020 Acute flaccid myelitis (AFM) is a serious neurologic condition that causes limb weakness or paralysis in previously healthy children. Since clusters of cases were first reported in 2014, nationwide surveillance has demonstrated sharp increases in AFM ...
Sarah Kidd +5 more
doaj +2 more sources