Results 51 to 60 of about 5,320 (189)

Epidemiological and Clinical Characteristics of the Enterovirus D68 Outbreak in Spain in 2024

open access: yesJournal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Enterovirus D68 (EV‐D68) is a significant cause of respiratory and neurological disease worldwide. In 2024, Spain experienced its largest recorded EV‐D68 outbreak, accounting for 37.4% of all typed EV (294/892). This study describes the epidemiological, clinical, and phylogenetic features of EV‐D68 infections.
Juan Camacho   +18 more
wiley   +1 more source

Enterovirus D68 capsid formation and stability requires acidic compartments

open access: yesmBio, 2023
Enterovirus D68 (EV-D68), a picornavirus traditionally associated with respiratory infections, has recently been linked to a polio-like paralytic condition known as acute flaccid myelitis.
Ganna Galitska   +5 more
doaj   +1 more source

Curcuminoids amplify host innate antiviral immunity via the CRYAB‐RBM26 axis in viral infection

open access: yesiMeta, Volume 5, Issue 1, February 2026.
DMC/CUR antagonize viral hijacking of host nucleic acid resources and finely regulate the induction and effector phases of the type I interferon (IFN‐I) pathway through the CRYAB‐RBM26 axis. This molecular axis serves as a key downstream regulator for DMC/CUR activation of the IFN‐I pathway.
Tingting Chen   +18 more
wiley   +1 more source

A Rare Clinical Manifestation of Disseminated Tuberculosis: Case Report of Tuberculous Meningitis With Flaccid Paralysis

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case highlights a rare presentation of disseminated tuberculosis in a child, manifesting as tuberculous meningitis and flaccid paralysis due to spinal tuberculosis. Timely initiation of antitubercular therapy, corticosteroids, and ventriculoperitoneal shunt placement led to full recovery, emphasizing tuberculosis consideration in atypical
Aisha Haleem   +5 more
wiley   +1 more source

A novel mucosal bivalent vaccine of EV-A71/EV-D68 adjuvanted with polysaccharides from Ganoderma lucidum protects mice against EV-A71 and EV-D68 lethal challenge

open access: yesJournal of Biomedical Science, 2023
Background Human enteroviruses A71 (EV-A71) and D68 (EV-D68) are the suspected causative agents of hand-foot-and-mouth disease, aseptic meningitis, encephalitis, acute flaccid myelitis, and acute flaccid paralysis in children.
Yu-Li Lin   +9 more
doaj   +1 more source

Acute flaccid myelitis: an emerging clinical entity [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2018
This commentary is on the original article by Gordon‐Lipkin et al. on pages 366–375 and the case series by Kirolos et al. on pages 376–380 of this issue.
Akihisa Okumura, Harushi Mori
openaire   +2 more sources

High‐Dependency Care Without Mechanical Ventilation for Severe Guillain–Barré Syndrome in a Rural Low‐Income Setting

open access: yesCase Reports in Critical Care, Volume 2026, Issue 1, 2026.
Guillain–Barré syndrome (GBS) is a major cause of neuromuscular respiratory failure globally. In many low‐income settings, access to mechanical ventilation and disease‐modifying therapy is limited. We describe the management of a young woman with rapidly progressive GBS and bulbar weakness in a mission hospital in northern Madagascar without access to ...
Lesley Notghi   +3 more
wiley   +1 more source

Assessment of acute motor deficit in the pediatric emergency room

open access: yesJornal de Pediatria (Versão em Português), 2017
Objectives: This review article aimed to present a clinical approach, emphasizing the diagnostic investigation, to children and adolescents who present in the emergency room with acute‐onset muscle weakness.
Marcio Moacyr Vasconcelos   +2 more
doaj   +1 more source

Efficacy and Safety of Plasmapheresis in Children With Acute Transverse or Flaccid Myelitis, and Guillain‐Barré Syndrome

open access: yesEuropean Journal of Neurology, Volume 32, Issue 11, November 2025.
17/23 (74%) children showed significant improvement at the end of TPE/IA 7/23 (30%) children had a full motor recovery TPE/IA sessions were well tolerated ABSTRACT Background Acute transverse myelitis (ATM), acute flaccid myelitis with polio‐like myeloradiculitis (AFM) and Guillain‐Barré syndrome (GBS) are severe neuroimmune disorders associated with ...
Alix Fleurance   +18 more
wiley   +1 more source

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