Results 1 to 10 of about 6,613 (193)

Firsekibart in acute gouty arthritis [PDF]

Journal of Translational Medicine
Yu Xue, Tianshu Chu, Jiankang Hu, Wei Gou, Ning Zhang, Juan Li, Jing Yu, Rongping Li, Rongbin Li, Long Qian, Xinwang Duan, Lihua Duan, Hejian Zou   +12 more
doaj   +4 more sources

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis [PDF]

Journal of Innate Immunity, 2023
PR domain-containing 1 with zinc finger domain (PRDM1) has been reported as a promoter of inflammation, which is a critical process involved in the pathogenesis of acute gouty arthritis.
Qingsong Zhao, Nan Xia, Jinmei Xu, Yingnan Wang, Luwen Feng, Dihan Su, Zhifeng Cheng   +6 more
doaj   +2 more sources

Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis. [PDF]

PLoS ONE
The tribological behaviour of articular cartilage plays a key role in joint motion; however, there is a gap in research on the effect of hyperuricemic joint fluid on cartilage friction behaviour in acute gouty arthritis.
Pai Zheng, Xueer Zhang, Chengcheng Feng, Yuhong Yu, Guangwei Che, Zhihong Cao, Li Tian, Yong Huang   +7 more
doaj   +2 more sources

AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis [PDF]

Frontiers in Pharmacology
BackgroundGout, a prevalent and severe form of arthritis precipitated by hyperuricemia, has been the subject of extensive research. However, the intricate underlying mechanisms governing gout-related inflammation are still only partially elucidated ...
Sijing Liu, Sijing Liu, Yongli Situ, Yongli Situ, Li Deng, Li Deng, Meng Liang, Meng Liang, Haoyuan He, Zheng Shao, Zheng Shao, Lifei Peng, Lifei Peng   +12 more
doaj   +2 more sources

Acute gouty arthritis of the atlantoaxial joint. [PDF]

Korean J Intern Med
Choi SJ, So MW, Lee S, Choi SW, Lim DH.
europepmc   +4 more sources

The application value of musculoskeletal ultrasound and dualenergy CT for monosodium urate crystals during the first episode of acute gouty arthritis [PDF]

Xin yixue, 2022
Objective To evaluate the application value of musculoskeletal ultrasound （MSUS） and dualenergy CT （DECT） in the detection of monosodium urate crystals during the first onset of acute gouty arthritis.
Chai Lan, Xu Senyin, Yuan Fang, Zhou Huadi, Dai Xiaona, Huang Yan, Bao Baosheng
doaj   +1 more source

MicroRNAs Involved in the Therapeutic Functions of Noni (Morinda citrifolia L.) Fruit Juice in the Treatment of Acute Gouty Arthritis in Mice Induced with Monosodium Urate

Foods, 2021
We investigated the functions of microRNAs in the therapeutic effects of noni (Morinda citrifolia L.) fruit juice on mouse models of acute gouty arthritis induced with monosodium urate (MSU). Compared with the model group (treated with MSU), mice in both
Xiaohong Li, Yue Liu, Yaming Shan, Yukun Wang, Zhandong Li, Yingxin Bi, Weihao Zhao, Yuhe Yin, Tianlong Wang, Shuang Li, Fengjie Sun, Changwu Chen, Hao Li   +12 more
doaj   +1 more source

Phospholipase A2 regulates autophagy in gouty arthritis: proteomic and metabolomic studies

Journal of Translational Medicine, 2023
Background Acute gouty arthritis is inflammatory joint arthritis. Gouty arthritis (GA) involves multiple pathological processes. Deposition of joints by monosodium urate (MSU) crystals has been shown to play a critical role in the injury process.
Weili Fu, Minghao Ge, Jian Li
doaj   +1 more source

(−)-Epicatechin Ameliorates Monosodium Urate-Induced Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and the NF-κB Signaling Pathway

Frontiers in Pharmacology, 2022
Background: Gouty arthritis is a common and complex inflammatory disease that will reduce the life quality of human beings (−)-Epicatechin (EC) is famous for antioxidant and anti-inflammatory activities. Thus, the aim of this study was to investigate the
Chenxi Wu, Fenfen Li, Xiaoxi Zhang, Wenjing Xu, Yan Wang, Yanjing Yao, Ziwei Han, Daozong Xia   +7 more
doaj   +1 more source

β-Caryophyllene Ameliorates MSU-Induced Gouty Arthritis and Inflammation Through Inhibiting NLRP3 and NF-κB Signal Pathway: In Silico and In Vivo

Frontiers in Pharmacology, 2021
Gouty arthritis serves as an acute reaction initiated by the deposition of monosodium urate (MSU) crystals around the joints. In this study, the anti-inflammatory effects of phytochemical β-caryophyllene on MSU crystal-induced acute gouty arthritis in ...
Wan-Yang Li, Fan Yang, Ji-Hua Chen, Guo-Feng Ren   +3 more
doaj   +1 more source