Results 21 to 30 of about 6,613 (193)
Studies on the Anti-Gouty Arthritis and Anti-hyperuricemia Properties of Astilbin in Animal Models
Open Chemistry, 2020 The purpose of this study was to investigate potential anti-gouty effect of astilbin (AS) and its possible mechanisms. In mice with hyperuricemia induced by potassium oxonate (OXO) and yeast extract powder (YEP), AS and febuxostat (FB) reduced the serum ...
Yan Han +6 more
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ETHORICOXIB IN THE TREATMENT OF RHEUMATIC DISEASES
Современная ревматология, 2010 Ethoricoxib is a new-generation selective COX-2 inhibitor. It has been recently licensed in Russia for the treatment of osteoarthrosis (OA), rheumatoid arthritis (RA), ankylosing spondylitis (AS), and acute gouty arthritis.
Yu A Olyunin, Yu A Olyunin
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Predicting anti-hyperuricemic and anti-gouty activities of fatty acids from Limonia acidissima L. fruit: In silico–in vivo study [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: As of today, the knowledge of the role of nutraceuticals in treating metabolic diseases such as hyperuricemia is still limited. Aims: To evaluate the mechanisms of anti-hyperuricemic and anti-gouty activity of Limonia acidissima in silico and
Rika Yusnaini +6 more
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Effects of Stephania hainanensis alkaloids on MSU-induced acute gouty arthritis in mice
BMC Complementary Medicine and Therapies, 2021 Background Gout is initiated by the precipitation of monosodium urate (MSU) crystals within the joints and soft tissues, and it can eventually cause acute or chronic arthritis.
Hao-fei Fan +8 more
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Journal of Orthopaedic Surgery and Research, 2022 Background To investigate the efficacy of Qingre Lishi Decoction(QLRD), in the treatment of acute gouty arthritis, and its influence on the expression levels of inflammatory factor nucleotide-binding oligomerization domain-like receptor(NALP 3) in ...
Jun Yu +3 more
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Medicina, 2021 Background and Objectives: Gouty arthritis is an acute inflammatory response caused by the precipitation of monosodium urate (MSU) crystals in joints. The triggering of MSU leads to increased production of inflammatory cytokines, such as interleukin-1β ...
Chih-Chien Wang +9 more
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Journal of Medical Sciences, 2023 Background: Renal insufficiency reduces the excretion of uric acid and inflammatory factors and exacerbates the structural deformities caused by gouty arthritis.
Zheng-Hao Huang +5 more
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Neutrophil extracellular trap clearance by synovial macrophages in gout
Arthritis Research & Therapy, 2021 Background Monosodium urate (MSU) crystals, i.e., the central etiological factors in gouty arthritis, induce the formation of neutrophil extracellular traps (NETs).
Ji Hye Jeong +7 more
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Suppressing chondrocyte cuproptosis by syringaresinol-4-O-β-d-glucoside alleviates gouty arthritis
Frontiers in PharmacologyBackgroundGouty arthritis is a rheumatic disease characterized by synovial inflammation and cartilage damage. Current therapeutic options for gouty arthritis, such as colchicine, primarily relieve the symptoms, which makes treatment challenging.MethodsWe
Shaotian Fu +11 more
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BMC Complementary and Alternative Medicine, 2017 Background The Gnaphalium pensylvanicum willd. is used in China as a folk medicine to treat anti-inflammatory, cough and rheumatism arthritis. The aim of this study was to evaluate the potential of the extract of G.
Yan Jiang +5 more
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