Results 91 to 100 of about 2,674,348 (298)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Peculiarities of Acute Intestinal Infections Epidemic Process in the Khabarovsk Territory under Conditions of Rainfall Flooding

Проблемы особо опасных инфекций, 2014
Analysis of the incidence rate over the past decade as regards acute intestinal infections in the Khabarovsk Territory has revealed unfavorable epidemiological situation on bacterial dysentery, enteric infections of rotavirus and undetermined etiology ...
V. A. Ott
doaj   +1 more source

The State of the Intestinal Microflora in Hospitalized Children with Acute Intestinal Infections

CHILDREN INFECTIONS, 2018
The purpose of this study was to study the state of the intestinal microflora in young children who received inpatient treatment for acute intestinal infections. A study of the microflora in 183 children aged 0 months. up to 3 years of life. At the same time, 43 (23.5%) children received breast milk, 53 (29.0%) were artificially fed and 87 (47.5 ...
Z. M. Kuliyeva, L. I. Rustamova, S. M. Faradzheva, M. G. Aliev, I. B. Israfilbekova, M. N. Mamedova, S. F. Suleymanova, F. V. Gylyndzhova   +7 more
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The aetiology of infectious intestinal disease in the community in Malta [PDF]

, 2010
Routine sources of data provide limited information on aetiological agents causing infectious intestinal disease (IID) in the community. A retrospective, age-stratified, cross-sectional, telephone study at community level was performed whereby identified
Gauci, Charmaine, Ruggieri, Franco-Maria, Mamo, Julian, Cuschieri, Liliana, Barbara, Christopher, Gilles, Herbert, Bartolo, Ilaria di   +6 more
core  

Aetiological role of viral and bacterial infections in acute adult lower respiratory tract infection (LRTI) in primary care [PDF]

, 2005
Background: Lower respiratory tract infections (LRTI) are a common reason for consulting general practitioners (GPs). In most cases the aetiology is unknown, yet most result in an antibiotic prescription.
McHugh, TD, Gillespie, S H, Creer, D.D., Wallace, P.G., McHugh, T.D., Gillespie, S.H., Creer, D D, Johnston, S.L., Johnston, AR, Wallace, P G, Johnston, A R, Dilworth, J P, Sanderson, G, Sanderson, G., Johnston, S L, Ling, C., Johnston, A.R., McHugh, T D, Creer, DD, Dilworth, JP, Patel, S, Dilworth, J.P., Gillespie, SH, Ling, C, Patel, S., Wallace, PG, Johnston, SL   +26 more
core   +1 more source

Markers of intestinal infection agents in patients with acute viral hepatitis with cholestatic syndrome

Терапевтический архив, 2011
Aim. To study the pathogenetic role of agents of the most common intestinal infections in the development of cholestatic syndrome in patients with acute viral hepatitis. Material and methods.
Svetlana Nikolaevna Zuevskaya, Ol'ga Fedorovna Belaya, Elena Bacil'evna Volchkova, Natal'ya Alekseevna Andrekayte, S N Zuevskaya, O F Belaya, E V Volchkova, N A Andrekaite   +7 more
doaj  

Exploring the gut microbiota’s crucial role in acute pancreatitis and the novel therapeutic potential of derived extracellular vesicles

Frontiers in Pharmacology
During acute pancreatitis, intestinal permeability increases due to intestinal motility dysfunction, microcirculatory disorders, and ischemia-reperfusion injury, and disturbances in the intestinal flora make bacterial translocation easier, which ...
Yijie Li, Jie Li, Sen Li, Shumin Zhou, Jiahua Yang, Ke Xu, Ke Xu, Yafeng Chen   +7 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Possibilities of Correction and Prophylaxis of Intestinal Microbiocenosis Disorders in Frequently Ill Children

Вопросы современной педиатрии, 2013
Frequently and protractedly ill children constitute a special for pediatricians group of patients. Acute respiratory infections with severe and frequently relapsing course badly affect children’s health and contribute to the decrease of the functional ...
A. N. Surkov
doaj   +1 more source