Results 71 to 80 of about 170,035 (293)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Rehabilitation of patients after acute intestinal infections [PDF]

, 2017
Дисбіотичні зміни відмічаються у більшості хворих, які перенесли гострі кишкові інфекції (ГКІ), особливо після антибактерійної терапії. При відсутності адекватної корекції вони зберігаються тривало.
Кондрин, О.Є., Дикий, Б.М., Мазурок, У.Я., Пришляк, О.Я.   +3 more
core  

Clinical, epidemiological and laboratory features of Salmonellosis in children at the present stage

Детские инфекции (Москва), 2019
In recent years, there has been an increase in the incidence of salmonellosis in children, including in the Yaroslavl region by 52.7%.In order to study salmonellosis in children at the present stage, we observed 185 patients aged from 1 month to 18 years
E. G. Klimovitskaya, S. N. Eshmolov, I. G. Sitnikov   +2 more
doaj   +1 more source

[Acute intestinal infections and hypertension].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1996
Some data on the specific features of the clinical course of acute enteric infections (AKI) and hypertensive disease (HD) are presented. The data indicate that the pathogenetic mechanisms of these diseases often act on the same points and in some cases in the same direction.
L E, Brodov, V V, Maleev, N D, Iushchuk
openaire   +1 more source

ACUTE INTESTINAL INFECTION AS A DISGUISE OF ACUTE APPENDICITIS IN CHILDREN

Pediatric pharmacology, 2016
The issue of differential diagnosis of acute appendicitis and acute intestinal infections in contemporary medicine remains relevant for clinical practice of surgeons and pediatricians. Late diagnosis of appendicitis results in development of complicated forms of vermiform appendix inflammation.
Y. Y. Dyakonova, I. V. Poddubniy, L. S. Namazova-Baranova, M. D. Bakradze, A. A. Gusev, A. S. Bekin   +5 more
openaire   +3 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The aetiology of infectious intestinal disease in the community in Malta [PDF]

, 2010
Routine sources of data provide limited information on aetiological agents causing infectious intestinal disease (IID) in the community. A retrospective, age-stratified, cross-sectional, telephone study at community level was performed whereby identified
Gauci, Charmaine, Ruggieri, Franco-Maria, Mamo, Julian, Cuschieri, Liliana, Barbara, Christopher, Gilles, Herbert, Bartolo, Ilaria di   +6 more
core  

Pathogenetic Mechanisms of Diarrhea in Children and Methods for Its Treatment

Zdorovʹe Rebenka, 2014
The paper presents the current views on the pathogenesis of acute intestinal infections in children and principles of therapy of diarrhea syndrome. Particular attention is paid to antisecretory therapy and the role of racecadotril in relieving diarrhea.
B.I. Krivuschev
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source