Results 61 to 70 of about 170,035 (293)

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Josiah I. Chung, Nutman, Thomas B, Barnes, MA, Josiah I Chung, Chung, Josiah I, Cooper, Philip J, Meera G. Nair (285902), Josiah I. Chung (682394), Nair, Meera G, Gang Chen (107840), Thomas B. Nutman, Nair, MG, Mali Camberis, Le Gros, G, Graham Le Gros, Mark A. Barnes (682393), Thomas B. Nutman (113195), Le Gros, Graham, Steel, C, Mark A Barnes, Jessica C. Jang (682391), Mitchell A. Lazar, Camberis, M, Thomas B Nutman, Meera G. Nair, Cathy Steel (180788), Jang, JC, Meera G Nair, Graham Le Gros (682396), Cooper, PJ, Jessica C Jang, Spencer H. Wang, Lazar, MA, Mitchell A Lazar, Spencer H. Wang (682392), Lazar, Mitchell A, Mark A. Barnes, Chen, Gang, Camberis, Mali, Mitchell A. Lazar (27888), Wang, SH, Gang Chen, Barnes, Mark A, Chen, G, Spencer H Wang, Philip J. Cooper, Wang, Spencer H, Mali Camberis (682395), Philip J. Cooper (218309), Chung, JI, Nutman, TB, Cathy Steel, Jang, Jessica C, Philip J Cooper, Steel, Cathy, Jessica C. Jang   +55 more
core   +1 more source

Contemporary issues epidemiology of acute intestinal infections of viral etiology in the north-eastern region of Ukraine

Журнал инфектологии, 2014
A retrospective epidemiological analysis of the incidence of acute intestinal infections in 2008–2012 in Sumy region. Indicators of the incidence ranged from 172,8 to 181,7 per 100 thousand of the population. Absolute growth of acute diarrheal infections
N. G. Malysh, N. D. Chemich, S. I. Doan, Yu. V. Khatynskaya, T. Yu. Kiry   +4 more
doaj   +1 more source

Acute Intestinal Ischemia in a Patient with COVID-19 Infection

The Korean Journal of Gastroenterology, 2020
The World Health Organization has declared novel coronavirus disease 2019 (COVID-19) a global public health emergency. Although respiratory symptoms predominate in COVID-19, thrombosis can occur in patients with COVID-19. This paper reports a case of an 82-year-old female with a prior medical history of hypertension, diabetes presenting with fever and ...
Balraj Singh, Ashesha Mechineni, Parminder Kaur, Nora Ajdir, Michael Maroules, Fayez Shamoon, Mahesh Bikkina   +6 more
openaire   +5 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Polymorphism of pro-inflammatory cytokine genes in acute intestinal infections

, 2021
Acute intestinal infections are widespread and hold the second place among infectious diseases, giving way solely to respiratory diseases. In this regard, much attention has been paid to examining acute intestinal infections, including immunopathogenetic
Y. A. Vitkovsky, A. N. Emelyanova, N. V. Epifantseva   +2 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effect of deworming on school-aged children's physical fitness, cognition and clinical parameters in a malaria-helminth co-endemic area of Côte d'Ivoire [PDF]

, 2014
Malaria and helminth infections are thought to negatively affect children's nutritional status and to impair their physical and cognitive development. Yet, the current evidence-base is weak.
Silué, Kigbafori D., Houngbedji, Clarisse A., Eveline Hürlimann, Giovanna Raso, N'Dri, Prisca B., Raso, Giovanna, Utzinger, Jürg, Coulibaly, Jean T., Prisca B N’Dri, Jean T Coulibaly, Dominique Bänninger, Clarisse A Houngbedji, Peiling Yap, Bänninger, Dominique, Yap, Peiling, N'Goran, Eliézer K., Hürlimann, Eveline, Kigbafori D Silué, Eliézer K N’Goran, Jürg Utzinger   +19 more
core   +1 more source

Current Approaches to the Treatment of Acute Intestinal Infections in Children

Zdorovʹe Rebenka, 2013
The article discussed in detail the following directions in the treatment of acute intestinal infections: rehydration, causal and supportive therapy. The indications to antibiotics in infectious diarrhea are given, attention was paid to use of probiotics.
L.V. Zakordonets, S.A. Kramarev, T.V. Beregovaya, A.N. Tolstanova, T.V. Dovbinchuk, A.V. Putnikov, T.M. Furzikova   +6 more
doaj   +1 more source