Results 61 to 70 of about 3,289,331 (190)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Experience of using vegetal enterosorbent in the treatment of acute intestinal infections
Журнал инфектологии, 2014 New approaches to pathogenetic therapy of acute intestinal infections remains a priority for clinical practice. Seventy one patients 71 with acute intestinal infections were include in the study.
D. A. Lioznov +4 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Diet therapy features for children with acute gastroenteritis
Медицинский совет, 2020 In the structure of infectious diseases in children, acute intestinal infections are only inferior to respiratory infections. The World Health Organization considers the effectiveness of only two therapeutic interventions to be absolutely proven: oral or
I. N. Zakharova, N. G. Sugyan
doaj +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
A METHOD FOR DIAGNOSING ACUTE INTESTINAL INFECTIONS IN NEWBORN
Детские инфекции (Москва), 2015 In this article development of mathematical model of diagnosis of sharp intestinal infections in newborn children depending on the nature of the infectious agent is described.
S. N. Beniova +5 more
doaj +1 more source
THE CLINICO-LABORATORY CHARACTERISTIC OF MIXED VIRAL INTESTINAL INFECTIONS IN CHILDREN IN BAKU CITY
Siberian Journal of Life Sciences and Agriculture, 2020 The aim of investigation was to study of epidemiological and clinical characteristics of mixed viral intestinal infections in children. The etiological diajnostic of acute intestinal infection of viral origin have been carried out by serological method ...
Lala Islakhovna Rustamova +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Environmental interventions and the pattern of geohelminth infections in Salvador, Brazil. [PDF]
, 2004 This paper reports a longitudinal study, conducted in 1989/90, of 1893 children aged 5 to 14 years in 9 poor urban areas of the city of Salvador (population 2.44 million), capital of Bahia State in northeast Brazil.
Moraes, LRS, Cairncross, S
core +1 more source