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AACN Advanced Critical Care, 2018
Acute ischemic stroke is a major cause of mortality and morbidity in the United States and worldwide. Despite the development of specialized stroke centers, mortality and morbidity as a result of acute ischemic strokes can and do happen anywhere. These strokes are emergency situations requiring immediate intervention.
Bryan, Boling, Katie, Keinath
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Acute ischemic stroke is a major cause of mortality and morbidity in the United States and worldwide. Despite the development of specialized stroke centers, mortality and morbidity as a result of acute ischemic strokes can and do happen anywhere. These strokes are emergency situations requiring immediate intervention.
Bryan, Boling, Katie, Keinath
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Treatment of acute ischemic stroke
Journal of Stroke and Cerebrovascular Diseases, 2001Acute ischemic stroke remains difficult to treat despite the advent of new therapies. The only approved medication to reverse its effects is recombinant tissue plasminogen activator administered intravenously within 3 hours of onset of stroke symptoms--an opportunity that does not often present itself. The principal drawback to thrombolytic therapy for
C, Lewandowski, W, Barsan
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Thrombolysis for Acute Ischemic Stroke
Current Topics in Medicinal Chemistry, 2009In the last decennium, thrombolytic therapy has changed the management of acute ischemic stroke. Randomized clinical studies have demonstrated that intravenous thrombolysis with tissue plasminogen activator improves functional outcomes. Recently the time window for intravenous thrombolysis has been extended from 3 to 4.5 hours after stroke onset, which
Uyttenboogaart, M +2 more
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Leukoaraiosis and acute ischemic stroke
European Journal of Neuroscience, 2021Abstract Ischaemic stroke is characterized by high morbidity, high disability rate, high mortality and high recurrence rate, which can have a grave impact on the quality of life of the patients and consequently becomes an economic burden on their families and society.
Xiaojia Tang +6 more
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New England Journal of Medicine, 2020
Key Clinical Points Acute Ischemic Stroke Treatment for patients with acute ischemic stroke is guided by the time from the onset of stroke, the severity of neurologic deficit, and findings on neuro...
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Key Clinical Points Acute Ischemic Stroke Treatment for patients with acute ischemic stroke is guided by the time from the onset of stroke, the severity of neurologic deficit, and findings on neuro...
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Management of acute ischemic stroke
Medicina Clínica (English Edition), 2023Ischemic stroke is a serious neurological condition that requires urgent attention. As a time-dependent disease, acute stroke management must be coordinated and effective to provide the best treatment as early as possible. The treatment of the acute phase of ischemic stroke includes general measures to ensure patient hemodynamic stability, the use of ...
Ricardo, Rigual +2 more
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Management of Acute Ischemic Stroke
Neurologic Clinics, 2008Stroke is the third leading cause of death and the leading cause of disability in the United States. This article summarizes the management of acute ischemic stroke, including conventional and novel therapies. The article provides an overview of the initial management, diagnostic work-up, treatment options, and supportive measures that need to be ...
Anna, Finley Caulfield +1 more
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Treatment of Acute Ischemic Stroke
New England Journal of Medicine, 2000Ischemic stroke exacts a heavy toll in death and disability worldwide. In the United States, where it is the third leading cause of death and the leading cause of serious long-term disability, approximately 750,000 strokes occur annually, with an annual mortality rate exceeding 150,000.1–4 In June 1996, the Food and Drug Administration (FDA) approved ...
T, Brott, J, Bogousslavsky
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Acute Treatment of Ischemic Stroke
Neurologic Clinics, 2022Ischemic stroke affects 2.5% of the population of the United States and is the leading cause of disability. This article outlines the evidence to support intravenous thrombolysis with alteplase and tenecteplase, thrombolysis in the setting of DWI/flair mismatch, endovascular treatment in the 6-hour and 6- to 24-hour window, and the use of telemedicine ...
Stephanie, Lyden, Jana, Wold
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Thrombolysis in Acute Ischemic Stroke
1996Thrombolysis is an attractive but potentially dangerous they for cerebral ischemia: it is capable of dissolving an arterial thrombus, but can also transform a pale infarct into a hematoma and/or may cause severe oedema and herniation. The safety and efficacy of the treatment critically depend on the timing of intervention ad on patient selection.
FIESCHI, Cesare +8 more
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