Results 81 to 90 of about 664,442 (399)

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Neuroimaging in Acute Schemic Stroke: Role and Recent Advances

대한영상의학회지, 2019
Neuroimaging plays a key role in assessing the detection of acute hemorrhage, diagnosis of infarct core, detection of steno-occlusive arteries, mismatch between infarct core and penumbra, and collateral circulation in patients with acute cerebral ...
Se Jin Cho, Seung Chai Jung, Chong Hyun Suh, Kyung Won Kim, Dong-Cheol Woo, Woo Yong Oh, Jong Gu Lee, Byung Jun Kim   +7 more
doaj   +1 more source

Comparative Characterization of Candidate Molecular Markers in Ischemic and Hemorrhagic Stroke

Общая реаниматология, 2021
According to epidemiological studies, the leading cause of morbidity, disability and mortality are cerebrovascular diseases, in particular ischemic and hemorrhagic strokes.
A. M. Golubev, A. V. Grechko, V. E. Zakharchenko, M. M. Kanarsky, M. V. Petrova, I. V. Borisov   +5 more
doaj   +1 more source

Data science of stroke imaging and enlightenment of the penumbra. [PDF]

, 2015
Imaging protocols of acute ischemic stroke continue to hold significant uncertainties regarding patient selection for reperfusion therapy with thrombolysis and mechanical thrombectomy.
Liebeskind, David S, Nour, May, Scalzo, Fabien   +2 more
core   +2 more sources

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute ischemic stroke

Journal of Neuroinflammation, 2019
Introduction In humans, a major component of natural killer (NK) and T cell target recognition depends on the surveillance of human leukocyte antigen (HLA) class I molecules by killer immunoglobulin-like receptors (KIRs).
Antonino Tuttolomondo, Domenico Di Raimondo, Rosaria Pecoraro, Alessandra Casuccio, Danilo Di Bona, Anna Aiello, Giulia Accardi, Valentina Arnao, Giuseppe Clemente, Vittoriano Della Corte, Carlo Maida, Irene Simonetta, Calogero Caruso, Rosario Squatrito, Antonio Pinto, on behalf of KIRIIND (KIR Infectious and Inflammatory Diseases) Collaborative Group   +15 more
doaj   +1 more source

One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke [PDF]

, 2016
BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke.
Albers, Gregory W., Amarenco, Pierre, Bornstein, Natan M., Canhão, Patrícia, Caplan, Louis R., Donnan, Geoffrey A., Ferro, José M., Hennerici, Michael G., Labreuche, Julien, Lavallée, Philippa C., Molina, Carlos, org Steering Committee, T. I. A. r. e. g. i. s. t. r. y., Rothwell, Peter M., Sissani, Leila, Steg, Philippe Gabriel, Toni, Danilo, Touboul, Pierre Jean, Uchiyama, Shinichiro, Vicaut, Éric, Wong, Lawrence K. S., Školoudík, David   +20 more
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Diagnostic performance of plasma D-dimer, fibrinogen, and D-dimer to fibrinogen ratio as potential biomarkers to predict hypertension-associated acute ischemic stroke

Heliyon
Background: Ischemic stroke is a common type of stroke that leads to death and functional disability in hypertensive patients. However, there are no well-studied non-invasive and less expensive fluid biomarkers routinely used to detect ischemic stroke in
Endeshaw Chekol Abebe, Tadesse Asmamaw Dejenie, Denekew Tenaw Anley, Misganaw Asmamaw Mengstie, Natnael Atnafu Gebeyehu, Getachew Asmare Adella, Gizachew Ambaw Kassie, Natnael Amare Tesfa, Molalegn Mesele Gesese, Sefineh Fenta Feleke, Melkamu Aderajew Zemene, Anteneh Mengist Dessie, Wubet Alebachew Bayih, Yenealem Solomon Kebede, Berihun Bantie, Mohammed Abdu Seid, Engidaw Fentahun Enyew, Gashaw Dessie, Dagnew Getnet Adugna, Teklie Mengie Ayele, Assefa Agegnehu Teshome, Fitalew Tadele Admasu   +21 more
doaj   +1 more source

Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke with and without metabolic syndrome. [PDF]

, 2014
OBJECTIVE: The aim of our study was to evaluate the associations between arterial stiffness indexes and immune-inflammatory markers in subjects with acute ischemic stroke with and without metabolic syndrome.
Arnao, V., Butt\ue0, C., Canino, B., Della Corte, V., DI RAIMONDO, D., Di Sciacca, R., Licata, G., Maida, C., Pecoraro, R., Pinto, A., Tuttolomondo, A.   +10 more
core   +2 more sources