Results 91 to 100 of about 2,149,646 (301)

Korelasi Rasio Kolesterol Total Terhadap HDL dengan Prediksi Outcome Stroke Iskemik Akut

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2018
Stroke is the leading cause of death in Indonesia with the significant increase in prevalence each year. The dominant stroke is ischemic stroke which is often caused by abnormal blood lipid profile which is the increase of total cholesterol to High ...
yuziani yuziani
doaj  

Comparison of High Density Lipid (Hdl) Cholesterol Levels In Acute Ischemic Stroke Patients with and Without Diabetes Mellitus

Pakistan Armed Forces Medical Journal
Objective: To compare HDL cholesterol levels among acute ischemic stroke patient with and without diabetes at tertiary care hospital of Rawalpindi. Study Design: Cross sectional study.
Sarah Khan, Malik Nadeem Azam Khan, Natasha Sarwar, Ambreen Nawaz, Muhammad Zahid Hussain, Hamid Mukhtar Butt   +5 more
doaj   +1 more source

NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II trials [PDF]

, 2008
<p><b>Background and Purpose:</b> In animal models of acute ischemic stroke (AIS), the free radical-trapping agent NXY-059 showed promise as a neuroprotectant.
Lees, K.R., Shuaib, A., Diener, H.C., Alderfer, V., Davis, S.M., Wasiewski, W., Lyden, P., Rodichok, L., Ashwood, T., Hardemark, H.G., Davalos, A., Grotta, J.   +11 more
core   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) [PDF]

, 2008
<p><b>Background and Purpose:</b> The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with ...
Wahlgren, N., Dávalos A, Hennerici MG, Kaste, M., N. Eriksson, Toni, Danilo, Bluhmki, Erich, N. Wahlgren, Hacke, Werner, Köhrmann, Martin, M. Kaste, Eriksson, Niclas, Aichner F, Ahmed N, Hacke W, Eriksson, N., Koehrmann, M., Bluhmki E, Grond M, F. Aichner, V. Larrue, G. A. Ford, D. Toni, Kaste M, Larrue, Vincent, Erila, T., Larrue, V., Eriksson, Niclas,, Aichner, F., M. G. Hennerici, Wahlgren, Nils, Davalos, A., Ford, Gary A, Grond, M., Toni, D., K. R. Lees, null null, Hennerici, Michael G, T. Erila, Roine, Risto O, Hacke, W., Koehrmann, Martin, Davalos, Antoni, Eriksson N, W. Hacke, Larrue V, Erilä, Terttu, A. Davalos, Aichner, Franz, Bluhmki, E., Wahlgren N, Roine RO, Machnig, T., M. Grond, Vanhooren, Geert, Ford, G.A., Roine, R.O., Hennerici, Michael G., Lees, K.R., Roine, Risto O., E. Bluhmki, Hennerici, M.G., Lees KR, Grond, Martin, Kaste, Markku, Köhrmann M, Peeters, André, Ahmed, Niaz, Machnig, Thomas, Machnig T, Vanhooren G., Erilä T, M. Kohrmann, Ahmed, N., R. O. Roine, Lees, Kennedy R., Ford GA, G. Vanhooren, Vanhooren, G., Lees, Kennedy R, Ford, Gary A., T. Machnig, N. Ahmed, Grond, M, Wahlgren, N,, Aichner, F, Erila, T, Hacke, W, Davalos, A, Eriksson, N, Ford, GA, Ahmed, N,, Bluhmki, E   +92 more
core   +1 more source

Early outcomes of thrombolysis for acute ischaemic stroke in a South African tertiary care centre [PDF]

, 2012
Includes abstract.Includes bibliographical references.Stroke is an important cause of death and disability in sub-Saharan Africa. Recombinant tissue plasminogen activator (tPA) thrombolysis is effective in treating acute ischaemic stroke, but may not be ...
Wasserman, Sean
core   +1 more source

Comparison of Regional Lepomeningeal Collateral Score and Tan Collateral Score in prediction of prognosis of anterior ischemic stroke with intravenous thrombolysis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To screen the related influencing factors of prognosis in acute anterior ischemic stroke patients who underwent intravenous thrombolysis, and to explore the predictive ability of two collateral scores based on CT angiography (CTA).
Yan CHEN, Jia-ju ZHAO, Bo WU
doaj   +1 more source

Role of SH levels and markers of immune response in the stroke [PDF]

, 2013
Background. Sulfhydryl groups (SH) are considered a key factor in redox sensitive reaction of plasma, and their modification could be considered an expression of abnormal generation of oxygen free radicals. Methods. Fifty consecutive patients with acute
Arru, Giannina, Gervasoni Jacopo, D’Addessi A, Minucci, Angelo, Fois, Maria Laura, Sotgiu, Stefano, Schiattarella Arcangelo, Cocci A, Angeletti, Silvia, Schiattarella, Arcangelo, Musumeci, Maria, Gambaro Giovanni, Persichilli S, Fois ML, Persichilli, Silvia, Musumeci, Salvatore, Primiano, Aniello, Ferraro Pm, Minucci A, Musumeci M, Angeletti S, Gambaro, Giovanni, Gervasoni, Jacopo, Ferraro, Pietro Manuel, Persichilli Silvia, Musumeci S., Primiano Aniello   +26 more
core   +1 more source

Thrombolysis and Thrombectomy in Acute Ischemic Stroke

, 2023
In the treatment of acute stroke, thrombolysis and thrombectomy have proven to be highly effective. Many patients have seen significant improvement after reperfusion therapy. This reprint aims to address current knowledge gaps and promote advancements in

core   +1 more source