Results 101 to 110 of about 884,542 (406)

Literature review of the mechanisms of acute kidney injury secondary to acute liver injury [PDF]

, 2022
People exposed to liver ischaemia reperfusion (IR) injury often develop acute kidney injury and the combination is associated with significant morbidity and mortality.
Davidson, B, Klootwijk, E, Platt, E, Robertson, F, Salama, A   +4 more
core   +1 more source

Biomarkers of Acute Kidney Injury [PDF]

Journal of Toxicology, 2011
Acute kidney injury (AKI) is a common problem in both the inpatient and outpatient setting and often results from drug toxicities. Traditional methods of identifying AKI, through measurement of blood urea nitrogen and serum creatinine, are problematic in that they are slow to detect decreases in glomerular filtration rate (GFR) and are influenced by a ...
Charles L. Edelstein, Jelena Klawitter, Jeffrey C. Sirota   +2 more
openaire   +4 more sources

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

Discovering Drug-Drug and Drug-Disease Interactions Inducing Acute Kidney Injury Using Deep Rule Forests [PDF]

arXiv, 2020
Patients with Acute Kidney Injury (AKI) increase mortality, morbidity, and long-term adverse events. Therefore, early identification of AKI may improve renal function recovery, decrease comorbidities, and further improve patients' survival. To control certain risk factors and develop targeted prevention strategies are important to reduce the risk of ...
arxiv  

Leonurine alleviates ferroptosis in cisplatin‐induced acute kidney injury by activating the Nrf2 signalling pathway

British Journal of Pharmacology, 2021
Evidence indicates that ferroptosis plays a key role in acute kidney injury induced by cisplatin. The Nrf2/NRF2 pathway regulates oxidative stress, lipid peroxidation and positively regulates cisplatin‐induced acute kidney injury, but its effect along ...
Jianqiang Hu, Wenjing Gu, Ning Ma, Xiaoye Fan, X. Ci   +4 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Review of the limitations of current biomarkers in acute kidney injury clinical practices

SAGE Open Medicine
Acute kidney injury is a prevalent disease in hospitalized patients and is continuously increasing worldwide. Various efforts have been made to define and classify acute kidney injury to understand the progression of this disease. Furthermore, deviations
Kendra B Bufkin, Zubair A Karim, Jeane Silva   +2 more
doaj   +1 more source

Determinants of urinary output response to IV furosemide in acute kidney injury [PDF]

, 2016
OBJECTIVES: This study assessed the determinants of urinary output response to furosemide in acute kidney injury; specifically, whether the response is related to altered pharmacokinetics or pharmacodynamics. DESIGN: Prospective cohort. SETTING:
Bagshaw, Bellomo, Bonventre, Brater, Calzavacca, Chawla, Coca, Endre, Hammarlund-Udenaes, Hasannejad, Herrera-Gutiérrez, Ho, Ho, Ho, Karvellas, Kunin, Lam, Leite, Levey, Mehta, Morgan, Murugan, Prandota, Prowle, Rose, Rosen, Rosen, Schmidt, Solomon, Wilson   +29 more
core   +2 more sources

Acute toxic kidney injury [PDF]

Renal Failure, 2019
Substances toxic to the kidney are legion in the modern world. The sheer number and variety, their mutual interactions and, metabolism within the body are a challenge to research. Moreover, the kidney is especially prone to injury owing to its physiology.
Nadezda Petejova, Nadezda Petejova, Vladimír Teplan, Josef Zadrazil, Arnošt Martínek   +4 more
openaire   +4 more sources

Biocompatibility of Water‐Dispersible Pristine Graphene and Graphene Oxide Using a Close‐to‐Human Animal Model: A Pilot Study on Swine

Advanced Healthcare Materials, EarlyView.
Graphene‐based materials are attracting considerable interest for biomedical applications. Analysis of their biocompatibility is required before their clinical translation, and swine represents an excellent close‐to‐human model. This study evaluates the toxicological and immunological impact of pristine graphene and graphene oxide through a compendium ...
Paola Nicolussi, Giovannantonio Pilo, Maria Giovanna Cancedda, Guotao Peng, Ngoc Do Quyen Chau, Alejandro De la Cadena, Renzo Vanna, Yarjan Abdul Samad, Tanweer Ahmed, Jeremia Marcellino, Giuseppe Tedde, Linda Giro, Acelya Ylmazer, Federica Loi, Gavina Carta, Loredana Secchi, Silvia Dei Giudici, Simona Macciocu, Dario Polli, Yuta Nishina, Ciriaco Ligios, Giulio Cerullo, Andrea Ferrari, Alberto Bianco, Bengt Fadeel, Giulia Franzoni, Lucia Gemma Delogu   +26 more
wiley   +1 more source