Prevention of acute kidney injury and protection of renal function in the intensive care unit : update 2017 [PDF]
Background: Acute kidney injury (AKI) in the intensive care unit is associated with significant mortality and morbidity. Objectives: To determine and update previous recommendations for the prevention of AKI, specifically the role of fluids, diuretics ...
Druml, W +8 more
core +3 more sources
Acute kidney injury following proton pump inhibitor therapy [PDF]
A 63-year-old male with a past medical history significant for hypertension for 12 years, stage 3 chronic kidney disease (baseline serum creatinine concentration, 1.4 mg/dl; estimated glomerular filtration rate, 54ml/min) secondary to hypertensive nephrosclerosis presented with generalized malaise and weakness for 2 weeks. He was referred for admission
Brewster, U.C., Perazella, M.A.
openaire +2 more sources
Micronutrient and amino acid losses in acute renal replacement therapy [PDF]
A wide range of renal replacement therapies is now available to support patients with acute kidney injury. These treatments utilize diffusion, convection or a combination of these mechanisms to remove metabolic waste products from the bloodstream.
Andrews +24 more
core +1 more source
Acute kidney injury in critically ill cancer patients : an update [PDF]
Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer itself or its treatment, these patients ...
Benoit, Dominique +3 more
core +2 more sources
Positive effects of a novel non-peptidyl low molecular weight radical scavenger in renal ischemia/reperfusion: a preliminary report [PDF]
Ischemia/reperfusion (I/R) is one of the most common causes of acute kidney injury. Reactive oxygen species have been recognized to be an important contributor to the pathogenesis of I/R injury.
A. Mocci +9 more
core +2 more sources
Use of Estimating Equations for Dosing Antimicrobials in Patients with Acute Kidney Injury Not Receiving Renal Replacement Therapy. [PDF]
Acute kidney injury (AKI) can potentially lead to the accumulation of antimicrobial drugs with significant renal clearance. Drug dosing adjustments are commonly made using the Cockcroft-Gault estimate of creatinine clearance (CLcr). The Modified Jelliffe
Awdishu, Linda +5 more
core +2 more sources
Translating Knowledge Into Therapy for Acute Kidney Injury [PDF]
No therapies have been shown to improve outcomes in patients with acute kidney injury (AKI). Given the high morbidity and mortality associated with AKI this represents an important unmet medical need. A common feature of all of the therapeutic development efforts for AKI is that none were driven by target selection or preclinical modeling that was ...
Mark, de Caestecker, Raymond, Harris
openaire +2 more sources
Systemic hypertension in cats with acute kidney injury [PDF]
Retrospective study of cats presenting to the Queen Mother Hospital for Animals, Royal Veterinary College with acute kidney injury between 2007 and 2015.
Acierno +28 more
core +2 more sources
Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury [PDF]
Cisplatin-induced acute kidney injury (CI-AKI) is a significant co-morbidity of chemotherapeutic regimens. While this condition is associated with substantially lower survival and increased economic burden, there is no pharmacological agent to effectively treat CI-AKI.
Ryan M. Williams +16 more
openaire +3 more sources
Acute kidney disease and renal recovery : consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup [PDF]
Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice.
A Dewitte +173 more
core +2 more sources

