Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study [PDF]
, 2015 Background: It is unclear how modifications in the way to calculate serum creatinine (sCr) increase and in the cut-off value applied, influences the prognostic value of Acute Kidney Injury (AKI).
Dhondt, Annemieke +4 more
core +2 more sources
Long Term Prognosis after Acute Kidney Injury (AKI) - What is the Role of Baseline Kidney Function and Recovery? A Systematic Review [PDF]
, 2015 Peer reviewedPublisher ...
Black, Corri +4 more
core +1 more source
Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery—development and validation of a risk score and effect of acute kidney injury on survival:observational cohort study [PDF]
, 2015 Funding: This study was funded by Tenovus Tayside, Chief Scientist Office, Scotland and a travelling fellowship from the Royal College of Physicians and Surgeons of Glasgow.
Bell, Samira +6 more
core +4 more sources
Novel regenerative therapy for acute kidney injury [PDF]
Renal Replacement Therapy, 2016 Acute kidney injury (AKI) is a renal disease that is associated with high mortality. Current treatments mostly rely on supportive therapies and do not directly target the disease. Regenerative medicine, however, offers potentially direct AKI therapy through two strategies: cell transplantation and kidney reconstruction.
Toyohara, Takafumi, Osafune, Kenji
openaire +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Cardiac-surgery associated acute kidney injury requiring renal replacement therapy. A Spanish retrospective case-cohort study [PDF]
, 2009 Acute kidney injury is among the most serious complications after cardiac surgery and is associated with an impaired outcome. Multiple factors may concur in the development of this disease.
Jose Ramon Perez-Valdivieso +5 more
core +2 more sources
Renal replacement therapy for acute kidney injury [PDF]
Renal Replacement Therapy, 2016 The annual incidence of acute kidney injury (AKI) has been increasing as the population ages. Despite advances in critical care and dialysis technology, the mortality remains unacceptably high in patients with AKI during the past few decades. Renal replacement therapy (RRT) is performed to treat patients with severe AKI and multiple organ failures, as ...
Negi, Shigeo +4 more
openaire +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Fenoldapam for Acute Kidney Injury in Children [PDF]
, 2008 We report two cases of children with severe cardiomyopathy requiring treatment with ventricular assist devices who developed acute kidney injury and were treated with fenoldopam.
Andreoli, Sharon P. +4 more
core +1 more source
Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]
, 2014 Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core +3 more sources