Results 21 to 30 of about 501,514 (307)

Acute kidney injury following proton pump inhibitor therapy [PDF]

Kidney International, 2007
A 63-year-old male with a past medical history significant for hypertension for 12 years, stage 3 chronic kidney disease (baseline serum creatinine concentration, 1.4 mg/dl; estimated glomerular filtration rate, 54ml/min) secondary to hypertensive nephrosclerosis presented with generalized malaise and weakness for 2 weeks. He was referred for admission
Brewster, U.C., Perazella, M.A.
openaire   +2 more sources

Probable tacrolimus toxicity from tibolone co-administration in a woman: a case report [PDF]

, 2010
Introduction: Tibolone is a synthetic steroid, used with increasing frequency to treat symptoms of menopause, including patients with solid-organ transplants who are taking concurrent immune suppression.
Carolyn J Clark, Carmel M Hawley, David W Mudge   +2 more
core   +2 more sources

Acute kidney injury associated with immune checkpoint inhibitor therapy: incidence, risk factors and outcomes

Journal for ImmunoTherapy of Cancer, 2020
Background Immune checkpoint inhibitors (ICPi) are a novel and promising anti-cancer therapy. There are limited data on the incidence, risk factors and outcomes of acute kidney injury (AKI) in patients receiving ICPi.
A. Meraz-Muñoz, E. Amir, P. Ng, C. Avila-Casado, Claire Ragobar, Christopher T. Chan, Joseph Kim, R. Wald, Ahbijat Kitchlu   +8 more
semanticscholar   +1 more source

Micronutrient and amino acid losses in acute renal replacement therapy [PDF]

, 2015
A wide range of renal replacement therapies is now available to support patients with acute kidney injury. These treatments utilize diffusion, convection or a combination of these mechanisms to remove metabolic waste products from the bloodstream.
Andrews, Btaiche, Casaer, Clase, Combs, Danzeisen, Fiaccadori, Filler, Heyland, Heyland, Iglesias, Jones, Kerr, Kosmadakis, Landucci, Leaf, Oh, Ronco, Shaban, Shibata, Stefanowicz, Thomas, Tucker, Umber, van Zanten   +24 more
core   +1 more source

Positive effects of a novel non-peptidyl low molecular weight radical scavenger in renal ischemia/reperfusion: a preliminary report [PDF]

, 2014
Ischemia/reperfusion (I/R) is one of the most common causes of acute kidney injury. Reactive oxygen species have been recognized to be an important contributor to the pathogenesis of I/R injury.
A. Mocci, A. Vergani, F. D&apos, J.V. Bonventre, M. Ben Nasr, M.B. Nasr, M.P. Rastaldi, P. Fiorina, R. Bassi, T. Ichimura   +9 more
core   +2 more sources

Prevention of acute kidney injury and protection of renal function in the intensive care unit : update 2017 [PDF]

, 2017
Background: Acute kidney injury (AKI) in the intensive care unit is associated with significant mortality and morbidity. Objectives: To determine and update previous recommendations for the prevention of AKI, specifically the role of fluids, diuretics ...
Druml, W, Forni, LG, Groeneveld, ABJ, Honore, PM, Hoste, Eric, Joannidis, M, Ostermann, M, Oudemans-van Straaten, HM, Schetz, Mathias   +8 more
core   +3 more sources

Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials.

The Lancet, 2020
BACKGROUND The timing of renal replacement therapy (RRT) for severe acute kidney injury is highly debated when no life-threatening complications are present. We assessed whether a strategy of delayed versus early RRT initiation affects 28-day survival in
S. Gaudry, D. Hajage, Nicolas Bénichou, K. Chaïbi, D. Dreyfuss   +4 more
semanticscholar   +1 more source

Translating Knowledge Into Therapy for Acute Kidney Injury [PDF]

Seminars in Nephrology, 2018
No therapies have been shown to improve outcomes in patients with acute kidney injury (AKI). Given the high morbidity and mortality associated with AKI this represents an important unmet medical need. A common feature of all of the therapeutic development efforts for AKI is that none were driven by target selection or preclinical modeling that was ...
Mark, de Caestecker, Raymond, Harris
openaire   +2 more sources

Acute kidney disease and renal recovery : consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup [PDF]

, 2017
Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice.
A Dewitte, A Ishani, A Ishani, A Morden, AB Pai, AG Schneider, AJ Lewington, Alexander Zarbock, AM Patel, AS Levey, Azra Bihorac, B Rodriguez-Iturbe, B Rodriguez-Iturbe, BB Newsome, BJ Philips, BS Moffett, C Mudumbai, C Ronco, C Vinsonneau, C-T Chao, CC Shiao, CJ Kirwan, Claudio Ronco, CM Bell, CM Horkan, CY Hsu, CY Hsu, D Korenkevych, D Ponce, D Schnell, David Bittleman, Dinna Cruz, DM Thomas, DW Brown, E Wang, EA Coleman, EA Hoste, EA Hoste, EA Hoste, ED Siew, ED Siew, ED Siew, ED Siew, ED Siew, Edward D. Siew, Eric Hoste, ES Kirkendall, Etienne Macedo, F Lapi, FG Brivet, GV do Nascimento, H de Geus, H Graf, H Schiffl, HL Smets, I Benz-de Bretagne, I Koulouridis, I Nachtigall, ID Bucaloiu, IH Khan, J Bouchard, J Bouchard, J Herrera, J Herrera, J Kaufman, J Zavada, JA Kellum, JA Kellum, JA Kellum, JA Kellum, Jay Koyner, JF Platt, JJ Dixon, JO Friedrich, John A. Kellum, JP Bosch, JP Nicholson, JR Brown, JR Brown, JR Prowle, JW Pickering, JW Pickering, K Doi, K Solez, Kathleen D. Liu, KD Liu, KR Pechman, L Cox, LA Tomlinson, Lakhmir S. Chawla, LJ Hickson, LS Chawla, LS Chawla, LS Chawla, LS Chawla, LS Chawla, Lui Forni, M Carlier, M Darmon, M Heung, M Heung, M Huber, M James, M Jun, M Monseu, M Xie, MA Onuigbo, Marlies Ostermann, MB Kwong, ME Matheny, Mitchell Rosner, Mitra Nadim, MM Chrymko, MM Sood, MT James, MT James, N Pannu, N Srisawat, Neesh Pannu, P Sharma, PA Duran, Patrick Murray, Paul M. Palevsky, PH van der Voort, PK Tao Li, PM Palevsky, PM Palevsky, R Cartin-Ceba, R Chu, R Jelliffe, R Rivosecchi, R Wald, R Wald, RA Parker, Ravindra Mehta, Rinaldo Bellomo, RK Basu, RL Amdur, RL Mehta, Robert L. Fitzgerald, Ron Wald, S Chen, S Ftouh, S Ninet, S Perinel, S Uchino, S Uchino, SA Silver, Sandra L. Kane-Gill, SC Gautam, Sean M. Bagshaw, SG Coca, SG Coca, SL Goldstein, SL Goldstein, SL Hu, SL Kane-Gill, SM Bagshaw, SM Handler, SM Jang, SM Lee, SM Moran, SP Kelleher, Stuart L. Goldstein, TJ Pianta, TY Wu, VC Wu, VC Wu, W Picard, Z Harel, ZH Endre, ZH Endre, ZL Cox, Zoltan Endre   +173 more
core   +2 more sources

Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury [PDF]

Frontiers in Pharmacology, 2022
Cisplatin-induced acute kidney injury (CI-AKI) is a significant co-morbidity of chemotherapeutic regimens. While this condition is associated with substantially lower survival and increased economic burden, there is no pharmacological agent to effectively treat CI-AKI.
Ryan M. Williams, Ryan M. Williams, Janki Shah, Elizabeth Mercer, Helen S. Tian, Vanessa Thompson, Justin M. Cheung, Madeline Dorso, Madeline Dorso, Jaclyn M. Kubala, Jaclyn M. Kubala, Lorraine J. Gudas, Elisa de Stanchina, Edgar A. Jaimes, Edgar A. Jaimes, Daniel A. Heller, Daniel A. Heller   +16 more
openaire   +3 more sources