Results 121 to 130 of about 1,012,052 (375)
Reticuloendothelial System Function Following Acute Liver Failure Induced by 90% Hepatectomy in the Rat [PDF]
Sepsis and bacterial infections are frequent complications of acute liver failure and following major liver resection. The mechanisms underlying this phenomenon are unclear. In this study, RES function and blood clearance of radiolabelled E.
Andersson, R+4 more
core +3 more sources
Background Combined iatrogenic vascular and biliary injury during cholecystectomy resulting in ischemic hepatic necrosis is a very rare cause of acute liver failure.
Goldaracena Nicolas+6 more
doaj +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Brain edema : a valid endpoint for measuring hepatic encephalopathy? [PDF]
Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease.
Bémeur, Chantal+5 more
core +1 more source
Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option.
David N. Perdigoto+7 more
doaj +1 more source
EASL Clinical Practice Guidelines on acute-on-chronic liver failure.
R. Moreau+11 more
semanticscholar +1 more source
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna+4 more
wiley +1 more source
Background Liver failure is usually associated with the inflammation and oxidation of hepatocytes. Due to their unique properties, graphene and graphene-based nanostructures such as magnetic graphene oxide (MGO) are useful in biomedicine and engineering.
Tahereh Foroutan+3 more
doaj +1 more source
Liver‐specific lncRNAs associated with liver cancers
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina+3 more
wiley +1 more source
Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study [PDF]
Mild hypothermia has a protective effect on brain edema and encephalopathy in both experimental and human acute liver failure. The goals of the present study were to examine the effects of mild hypothermia (35°C) on brain metabolic pathways using ...
Butterworth, Roger+4 more
core +1 more source