Results 131 to 140 of about 386,804 (284)

Brain CT Scan Diagnostic and Prognostic Value in Patients With Acute Liver Failure and Cerebral Edema: A Multicenter Cohort Study.

open access: yes
OBJECTIVE: Patients with acute liver failure (ALF) may develop cerebral edema. We aimed to study the CT scan diagnostic and prognostic value among patients with ALF and cerebral edema. DESIGN: International multicenter retrospective cohort. SETTING: U.S.
Study Group, U.S. Acute Liver Failure   +4 more
core   +1 more source

Acute liver failure in children: A regional experience

open access: yes, 2003
Objective: To review the outcome of acute liver failure (ALF) and the effect of liver transplantation in children in Australia. Methodology: A retrospective review was conducted of all paediatric patients referred with acute liver failure between 1985 ...
Strong, R. W.   +7 more
core   +1 more source

Plasmin-mediated proteolysis of von Willebrand factor in patients with acute and chronic liver disease

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: In patients with acute and chronic liver disease, von Willebrand factor (VWF) antigen levels are markedly elevated, whereas a disintegrin and metalloproteinase with thrombospondin type 1 motifs, member 13 (ADAMTS13) activity is often reduced.
Hinde El Otmani   +6 more
doaj   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Definitions of Acute-On-Chronic Liver Failure: The Past, the Present, and the Future

open access: yes, 2015
Acute-on-chronic liver failure (ACLF) is an entity used to define patients with liver cirrhosis presenting with acute decompensation. For over 20 years, ACLF has taken multiple definitions and/or classifications.
Roland Amathieu, Ali Al-Khafaji
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Liver transplantation for acute liver failure and acute-on-chronic liver failure

open access: yesAmerican Journal of Transplantation
Acute liver failure (ALF) and acute-on-chronic liver (ACLF) are distinct phenotypes of liver failure and, thus, need to be compared and contrasted for appropriate management. There has been a significant improvement in the outcomes of these patients undergoing liver transplantation (LT).
Anand V. Kulkarni   +2 more
openaire   +2 more sources

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Hepatitis E virus infection in the perspective of acute-on-chronic liver failure

open access: yes, 2017
Introduction: Hepatitis E virus is a non-enveloped virus measuring 27 to 34nm, which belongs to the hepeviridae family. Its transmission is predominantly fecal oral and it is a common cause of acute viral hepatitis worldwide.
Sekawi, Zamberi   +3 more
core  

Liver progenitor cell line HepaRG differentiated in a bioartificial liver effectively supplies liver support to rats with acute liver failure.

open access: yes, 2012
A major roadblock to the application of bioartificial livers is the need for a human liver cell line that displays a high and broad level of hepatic functionality.
Oude Elferink, R.P.   +35 more
core   +1 more source

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