Results 21 to 30 of about 1,006,426 (373)
Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors. [PDF]
PLoS ONE, 2015 Acetaminophen (APAP) hepatotoxicity is related to the formation of N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified through conjugation with reduced glutathione (GSH).
Gurnit Kaur +6 more
doaj +1 more source
The Indian Journal of Pediatrics, 2006 Acute liver failure in children is a rare but potentially fatal disease. Causes of ALF in neonatal period are different from those in early or late childhood. Despite the improvement in the paediatric intensive care, liver transplantation remains the only effective treatment.
Bansal, Sanjay, Dhawan, Anil
openaire +2 more sources
Alimentary Pharmacology and Therapeutics, 2022 Previous studies suggested increased mortality in patients with hepatorenal syndrome type 1 (HRS1) and advanced acute‐on‐chronic liver failure (ACLF).
F. Wong +6 more
semanticscholar +1 more source
Acute Liver Failure Secondary to Hepatic Infiltration of Malignant Melanoma [PDF]
Clinical Endoscopy, 2022 Acute liver failure due to malignant melanoma is uncommon. We presents a case of acute liver failure secondary to hepatic infiltration of a malignant melanoma.
Yujin Lee +7 more
doaj +1 more source
Liver transplantation in acute liver failure: Dilemmas and challenges
World journal of transplantation, 2021 Acute liver failure (ALF) refers to a state of severe hepatic injury that leads to altered coagulation and sensorium in the absence of pre-existing liver disease. ALF has different causes, but the clinical characteristics are strikingly similar.
Ramesh Kumar, U. Anand, R. Priyadarshi
semanticscholar +1 more source
HPB Surgery, 1999 To consider the classification and to present an approach to the diagnosis and management of complications associated with acute liver failure.A review of studies reported from 1966 to 1998 and identified through a MEDLINE search on treatment of acute liver failure.Acute liver failure can be subdivided into hyperacute, (encephalopathy within 7 days of ...
Lee, William M., Williams, Roger
openaire +4 more sources
Frontiers in Pediatrics, 2022 IntroductionPediatric acute liver failure is a rare and serious disease. Though liver transplantation is considered as the established treatment option for patients who are unlikely to recover with medical management, however, with the advancement of ...
Puja Amatya +6 more
doaj +1 more source
Cell Death and Disease, 2020 Acetaminophen (APAP) overdose is a common cause of drug-induced acute liver failure. Although hepatocyte cell death is considered to be the critical event in APAP-induced hepatotoxicity, the underlying mechanism remains unclear.
Naoya Yamada +14 more
semanticscholar +1 more source
Seminars in Respiratory and Critical Care Medicine, 1993 Acute liver failure (ALF) (sometimes referred to as fulminant hepatic failure) is a clinical syndrome from a variety of causes resulting from rapid loss in hepatocyte function, typically associated with coagulopathy and encephalopathy in a patient without preexisting liver disease or cirrhosis. Cerebral edema is a cardinal feature and may produce uncal
openaire +4 more sources
Novel Therapeutic Approaches against Acetaminophen-induced Liver Injury and Acute Liver Failure.
Toxicological Sciences, 2020 Liver injury and acute liver failure caused by acetaminophen (APAP) overdose is a significant clinical problem in most western countries. The only clinically approved antidote is N-acetylcysteine (NAC), which promotes the recovery of hepatic GSH.
H. Jaeschke +3 more
semanticscholar +1 more source