Results 41 to 50 of about 653,174 (341)

Death and Liver Transplantation within Two Years of Onset of Drug-Induced Liver Injury [PDF]

, 2017
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset.
Anania, Andrade, Bjornsson, Chalasani, Fontana, Fontana, Fontana, Fontana, Gustot, Jalan, Karvellas, Lee, Lee, Martinez, Medina-Caliz, Olson, Ostapowicz, Robles-Diaz, Rockey, Stickel, Stravitz, Zimmerman   +21 more
core   +2 more sources

Two sides of one coin: massive hepatic necrosis and progenitor cell-mediated regeneration in acute liver failure

Frontiers in Physiology, 2015
Massive hepatic necrosis is a key event underlying acute liver failure, a serious clinical syndrome with high mortality. Massive hepatic necrosis in acute liver failure has unique pathophysiological characteristics including extremely rapid parenchymal ...
Honglei eWeng, Xiaobo eCai, Xiaodong eYuan, Roman eLiebe, Steven eDooley, Hai eLi, Tai-Ling eWang   +6 more
doaj   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Acute liver failure in adults [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2019
This article summarizes data on etiology, epidemiology and clinical presentation of acute liver failure. The review provides statistics on the incidence rates of acute liver failure in patients with different underlying diseases, describes the most ...
Lukashik S.P., Karpov I.A.
doaj   +1 more source

Issues of intensive care and liver transplantation tactics in fulminant liver failure

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Fulminant liver failure is usually characterized as severe acute liver injury with encephalopathy and synthetic dysfunction (international normalized ratio [INR] ≥1.5) in a patient without cirrhosis or previous liver disease.
L. U. Agumava, V. A. Gulyaev, K. N. Lutsyk, O. D. Olisov, R. B. Akhmetshin, K. M. Magomedov, B. I. Kazymov, A. R. Akhmedov, K. F. Alekberov, B. I. Yaremin, M. S. Novruzbekov   +10 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Prognostic markers in acute liver failure - Alpha feto protein

Archives of Medicine and Health Sciences, 2021
Background and Aim: Acute liver failure is associated with high mortality and only about 40% patients survive without liver transplantation. The available prognostic models failed to predict the outcome correctly.
P Gayathri, Smitha Krishnamoorthy, Subhash Chandra, M G K Pillai, Raviraj Menon, Mahesh Subramania Iyer   +5 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Liver transplantation for late-onset presentations of acute liver failure in Wilson's disease: The UK experience over 2 decades

JHEP Reports, 2020
Background & Aims: Acute liver failure as the initial presentation of Wilson’s disease is usually associated with onset in childhood, adolescence or early adulthood.
Samuel Shribman, Gwilym Webb, Rhiannon Taylor, Thomas T. Warner, Adam Duckworth, Alexander Gimson, Achuth Shenoy, William Griffiths   +7 more
doaj   +1 more source