Results 71 to 80 of about 1,006,426 (373)
Issues of intensive care and liver transplantation tactics in fulminant liver failure
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023 Fulminant liver failure is usually characterized as severe acute liver injury with encephalopathy and synthetic dysfunction (international normalized ratio [INR] ≥1.5) in a patient without cirrhosis or previous liver disease.
L. U. Agumava +10 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Acute Liver Failure: An Up-To-Date Approach [PDF]
, 2017 Acute liver failure is a rare but potentially devastating disease. Throughout the last few decades, acute liver failure outcomes have been improving in the context of the optimized overall management.
Bagulho, L +3 more
core +1 more source
Acute Liver Failure (ALF) in Pregnancy: How Much Is Pregnancy Related?
Hepatology, 2020 Acute liver failure (ALF), characterized by sudden onset of coagulopathy (international normalized ratio [INR] ≥ 1.5) and encephalopathy, may occur during pregnancy either as a pregnancy‐associated etiology or an unrelated and coincidental liver injury ...
Lisa C. Casey +7 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy. [PDF]
, 2016 Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver ...
Decker, Kerry A +5 more
core +1 more source
Case Reports in Gastroenterology, 2012 In acute attacks of acute intermittent porphyria, the mainstay of treatment is glucose and heme arginate administration. We present the case of a 58-year-old patient with acute liver failure requiring urgent liver transplantation after erroneous 6-fold ...
Pascal Frei +10 more
doaj +1 more source
Prognostic markers in acute liver failure - Alpha feto protein
Archives of Medicine and Health Sciences, 2021 Background and Aim: Acute liver failure is associated with high mortality and only about 40% patients survive without liver transplantation. The available prognostic models failed to predict the outcome correctly.
P Gayathri +5 more
doaj +1 more source
Gastroenterology, 2019 BACKGROUND & AIMS Acetaminophen overdose is a major cause of acute liver failure (ALF). Mitochondrial SH3BP5 (also called SAB) and phosphorylation of JNK mediate the hepatotoxic effects of acetaminophen.
S. Torres +19 more
semanticscholar +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source