Results 81 to 90 of about 1,006,426 (373)
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Acute and chronic renal failure in liver transplantation [PDF]
We have performed a retrospective review of the incidence and etiologies of acute renal failure (ARF) in 105 adult patients receiving liver transplants. The prevalence of chronic renal failure was also determined. ARF occurred in 94.2% of these patients.
McCauley, J+3 more
core +1 more source
Longterm Outcomes of Patients Undergoing Liver Transplantation for Acute‐on‐Chronic Liver Failure
Recent data have demonstrated >80% 1‐year survival probability after liver transplantation (LT) for patients with severe acute‐on‐chronic liver failure (ACLF). However, longterm outcomes and complications are still unknown for this population.
V. Sundaram+13 more
semanticscholar +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Death and Liver Transplantation within Two Years of Onset of Drug-Induced Liver Injury [PDF]
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset.
Anania+21 more
core +2 more sources
NBAS mutations cause acute liver failure: when acetaminophen is not a culprit
Background Pediatric acute-liver-failure due to acetaminophen (APAP) administration at therapeutic dosage is rare, while viral infections and metabolic defects are the prevalent causes. Yet, as acetaminophen is routinely used in febrile illnesses, it may
Pier Luigi Calvo+7 more
doaj +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Liver Transplantation for Acute‐on‐Chronic Liver Failure: Science or Fiction?
Acute clinical deterioration of a patient with chronic liver disease remains a decisive time point both in terms of medical management and prognosis. This condition, also known as acute decompensation (AD), is an important event determining a crossroad ...
J. Trebicka+4 more
semanticscholar +1 more source
Orthotopic liver transplantation for fulminant and subacute hepatic failure [PDF]
Fulminant and subacute hepatitis are conditions characterized by rapid liver failure, which can lead to death in 80 to more than 95% of the cases with medical supportive care only.
Iwatsuki, S, Starzl, TE, Stieber, AC
core