Results 101 to 110 of about 542,420 (309)

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source

Transfusion-related acute lung injury – afrequently undiagnosed reaction following transfusion ofblood components

Pediatria i Medycyna Rodzinna, 2015
Transfusion-related acute lung injury is the leading cause of mortality following transfusion of blood components. Its characteristic feature is acute hypoxaemia during or 6 hours after transfusion.
Jolanta Korsak, Anna Łata
doaj   +1 more source

Pathophysiological aspects of severe acute pancreatitis-associated lung injury [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2005
Acute pancreatitis is an inflammatory process which occurs in severe form in 20% of all patients, out of whom 1596-25% will die. The incidence of severe acute pancreatitis-associated lung injury (APALI) varies from 15% to 55% and its severity varies from
Šurbatović Maja, Jovanović Krsta, Radaković Sonja, Filipović Nikola   +3 more
doaj   +1 more source

Neutrophil elastase inhibitor (sivelestat) may be a promising therapeutic option for management of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID‐19

Journal of Clinical Pharmacy and Therapeutics, 2020
This article summarizes the effects of sivelestat on acute lung injury/acute respiratory distress syndrome (ALI/ARDS) or ARDS with coagulopathy, both of which are frequently seen in patients with COVID‐19.
Adeleh Sahebnasagh, F. Saghafi, Mohammadreza Safdari, M. Khataminia, Afsaneh Sadremomtaz, Zeinab Talaei, Hassan Rezai Ghaleno, Mahdi Bagheri, S. Habtemariam, Razieh Avan   +9 more
semanticscholar   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

Advanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan, Lei Wu, Dong Zhang, Linxiao Wu, Graca Ferreira Vaz Pinto Mendes, Wanqiao J. Tu, Heping Ma, Toby J. Proctor, Colin R. Butler, Thomas Kjærgaard, Mark W. Lowdell, Martin A. Birchall, Robert E. Hynds, Richard Hewitt, Wenhui Song   +14 more
wiley   +1 more source

Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure

Nature Communications
Respiratory infection by Pseudomonas aeruginosa, common in hospitalized immunocompromised and immunocompetent ventilated patients, can be life-threatening because of antibiotic resistance.
Sudipta Das, Tomasz W. Kaminski, Brent T. Schlegel, William Bain, Sanmei Hu, Akruti Patel, Sagar L. Kale, Kong Chen, Janet S. Lee, Rama K. Mallampalli, Valerian E. Kagan, Dhivyaa Rajasundaram, Bryan J. McVerry, Prithu Sundd, Georgios D. Kitsios, Anuradha Ray, Prabir Ray   +16 more
doaj   +1 more source

Optical Imaging of Lipopolysaccharide-induced Oxidative Stress in Acute Lung Injury from Hyperoxia and Sepsis [PDF]

, 2013
Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants.
Audi, Said H., Eis, Annie L., Konduri, Girija G., Maleki, Sepideh, Ranji, Mahsa, Sepehr, Reyhaneh, Staniszewski, Kevin   +6 more
core   +3 more sources

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Use of pressure muscle index to predict the contribution of patient’s inspiratory effort during pressure support ventilation: a prospective physiological study

Frontiers in Medicine
BackgroundThe successful implementation of assisted ventilation depends on matching the patient’s effort with the ventilator support. Pressure muscle index (PMI), an airway pressure based measurement, has been used as noninvasive monitoring to assess the
Ran Gao, Ran Gao, Jian-Xin Zhou, Yan-Lin Yang, Shan-Shan Xu, Yi-Min Zhou, Linlin Zhang, Ming-Yue Miao   +7 more
doaj   +1 more source

Ligation of protease-activated receptor 1 enhances alpha(v)beta(6) integrin-dependent TGF-beta activation and promotes acute lung injury [PDF]

, 2006
Activation of latent TGF-beta by the alpha(v)beta(6) integrin is a critical step in the development of acute lung injury. However, the mechanism by which a alpha(v)beta(6)-mediated TGF-beta activation is regulated has not been identified.
Camerer, E, Chambers, RC, Davis, GE, Jenkins, RG, Laurent, GJ, Matthay, MA, Scotton, CJ, Sheppard, D, Su, G, Su, X   +9 more
core