Results 11 to 20 of about 318,103 (313)

Immunotherapy strategies and prospects for acute lung injury: Focus on immune cells and cytokines

open access: yesFrontiers in Pharmacology, 2022
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a disastrous condition, which can be caused by a wide range of diseases, such as pneumonia, sepsis, traumas, and the most recent, COVID-19.
Wenfang Zhu, Yiwen Zhang, Yinghong Wang
doaj   +2 more sources

Pathogenesis of pneumonia and acute lung injury

open access: yesClinical science, 2022
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary and critical care healthcare professionals, and these challenges have recently garnered global attention due to the ongoing Sars-CoV-2 pandemic.
Matthew E. Long   +2 more
semanticscholar   +1 more source

Panaxydol attenuates ferroptosis against LPS-induced acute lung injury in mice by Keap1-Nrf2/HO-1 pathway

open access: yesJournal of Translational Medicine, 2021
Background Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) induces uncontrolled and self-amplified pulmonary inflammation, and has high morbidity and mortality rates in critically ill patients.
Jiucui Li   +9 more
semanticscholar   +1 more source

Acute lung injury - from pathophysiology to treatment.

open access: yesPhysiological Research, 2021
Acute lung injury is characterized by acute respiratory insufficiency with tachypnea, cyanosis refractory to oxygen, decreased lung compliance, and diffuse alveolar infiltrates on chest X-ray.
D. Mokra
semanticscholar   +1 more source

Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report

open access: yesAmerican Journal of Respiratory Cell and Molecular Biology, 2022
Advancements in methods, technology, and our understanding of the pathobiology of lung injury have created the need to update the definition of experimental acute lung injury (ALI).
H. Kulkarni   +49 more
semanticscholar   +1 more source

The role of neutrophil extracellular traps in acute lung injury

open access: yesFrontiers in Immunology, 2022
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high morbidity and mortality. Neutrophils play a key role in the development of different forms of ALI, and the release of neutrophil extracellular traps (NETs) is emerging
D. Scozzi   +4 more
semanticscholar   +1 more source

STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway

open access: yesCell Death and Disease, 2022
Compelling evidences have revealed the emerging role of ferroptosis in the pathophysiological process of acute lung injury (ALI), but its modulation is not clear.
Youjing Yang   +7 more
semanticscholar   +1 more source

Extracellular vesicles in the pathogenesis and treatment of acute lung injury

open access: yesMilitary Medical Research, 2022
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-threatening lung diseases associated with acute and severe inflammation.
Qian Hu   +7 more
semanticscholar   +1 more source

Locally organised and activated Fth1hi neutrophils aggravate inflammation of acute lung injury in an IL-10-dependent manner

open access: yesNature Communications, 2022
Acute respiratory distress syndrome (ARDS) is a common respiratory critical syndrome with no effective therapeutic intervention. Neutrophils function in the overwhelming inflammatory process of acute lung injury (ALI) caused by ARDS; however, the ...
Kun Wang   +11 more
semanticscholar   +1 more source

Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection

open access: yesJCI Insight, 2022
Severe acute lung injury has few treatment options and a high mortality rate. Upon injury, neutrophils infiltrate the lungs and form neutrophil extracellular traps (NETs), damaging the lungs and driving an exacerbated immune response.
J. M. Adrover   +12 more
semanticscholar   +1 more source

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