Results 1 to 10 of about 123,923 (170)

A case of therapy-related acute lymphoblastic leukemia following the treatment of acute myeloid leukemia

Leukemia Research Reports, 2022
Therapy-related acute lymphoblastic leukemia represents a distinct entity associated with inferior survival compared with de novo acute lymphoblastic leukemia.
Sufana Shikdar, Yuan Ying, Mohamad Khawandanah   +2 more
doaj   +1 more source

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia. [PDF]

PLoS ONE, 2015
Osteonecrosis is one of the most common, serious, toxicities resulting from the treatment of acute lymphoblastic leukemia. In recent years, pediatric acute lymphoblastic leukemia clinical trials have used discontinuous rather than continuous dosing of ...
Laura B Ramsey, Laura J Janke, Monique A Payton, Xiangjun Cai, Steven W Paugh, Seth E Karol, Landry Kamdem Kamdem, Cheng Cheng, Richard T Williams, Sima Jeha, Ching-Hon Pui, William E Evans, Mary V Relling   +12 more
doaj   +1 more source

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]

, 2012
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
zur Stadt, Udo, Groiss, Volker, Schneider, Katja, Renier J Brentjens, Nadia Terziyska, Harald Ehrhardt, Jeremias, I., Brentjens, Renier J., Farkasova, K., Katja Schneider, Volker Groiss (106787), Katarina Farkasova (106794), Ehrhardt, Harald, Wagner, E., Renier J. Brentjens (106801), Quintanilla-Martinez, Leticia, Martin Horstmann (45040), Ehrhardt, H., Ernst Wagner (60760), Wagner, Ernst, Leticia Quintanilla-Martinez (33277), Terziyska, N., Katja Schneider (106791), Horstmann, M., Brentjens, R.J., Catarina Castro Alves, Quintanilla-Martinez, L., Zur Stadt, U., Horstmann, Martin, Schneider, K., Ogris, M., Manfred Ogris, Alves, C.C., Nadia Terziyska (106777), Terziyska, Nadia, Jeremias, Irmela, Groiss, V., Irmela Jeremias (106806), Volker Groiss, Udo zur Stadt, Martin Horstmann, Farkasova, Katarina, Ernst Wagner, Irmela Jeremias, Ogris, Manfred, Udo zur Stadt (106803), Catarina Castro Alves (106783), Manfred Ogris (60759), Castro Alves, Catarina, Katarina Farkasova, Leticia Quintanilla-Martinez, Harald Ehrhardt (106798)   +51 more
core   +1 more source

CD123 expression patterns and selective targeting with a CD123-targeted antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia

Haematologica, 2019
The potential of CD123-targeted therapies in acute lymphoblastic leukemia/lymphoma remains largely unexplored. We examined CD123 expression levels in a large cohort of patients with acute lymphoblastic leukemia/lymphoma and assessed the in vitro impact ...
Evgeniya Angelova, Charlene Audette, Yelena Kovtun, Naval Daver, Sa A. Wang, Sherry Pierce, Sergej N. Konoplev, Haitham Khogeer, Jeffrey L. Jorgensen, Marina Konopleva, Patrick A. Zweidler-McKay, L. Jeffrey Medeiros, Hagop M. Kantarjian, Elias J. Jabbour, Joseph D. Khoury   +14 more
doaj   +1 more source

Rationale for an international consortium to study inherited genetic susceptibility to childhood acute lymphoblastic leukemia

Haematologica, 2011
Acute lymphoblastic leukemia is the major pediatric cancer in developed countries. To date most association studies of acute lymphoblastic leukemia have been based on the candidate gene approach and have evaluated a restricted number of polymorphisms ...
Amy L. Sherborne, Kari Hemminki, Rajiv Kumar, Claus R. Bartram, Martin Stanulla, Martin Schrappe, Eleni Petridou, Ágnes F. Semsei, Csaba Szalai, Daniel Sinnett, Maja Krajinovic, Jasmine Healy, Marina Lanciotti, Carlo Dufour, Stefania Indaco, Eman A El-Ghouroury, Ruchchadol Sawangpanich, Suradej Hongeng, Samart Pakakasama, Anna Gonzalez-Neira, Evelia L. Ugarte, Valeria P. Leal, Juan P.M. Espinoza, Azza M. Kamel, Gamal T.A. Ebid, Eman R. Radwan, Serap Yalin, Erdinc Yalin, Mehmet Berkoz, Jill Simpson, Eve Roman, Tracy Lightfoot, Fay J. Hosking, Jayaram Vijayakrishnan, Mel Greaves, Richard S. Houlston   +35 more
doaj   +1 more source

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies

Haematologica, 2018
The prognostic value of minimal residual disease (MRD) in Philadelphia-chromosome-positive (Ph+) childhood acute lymphoblastic leukemia (ALL) treated with tyrosine kinase inhibitors is not fully established.
Giovanni Cazzaniga, Paola De Lorenzo, Julia Alten, Silja Röttgers, Jeremy Hancock, Vaskar Saha, Anders Castor, Hans O. Madsen, Virginie Gandemer, Hélène Cavé, Veronica Leoni, Rolf Köhler, Giulia M. Ferrari, Kirsten Bleckmann, Rob Pieters, Vincent van der Velden, Jan Stary, Jan Zuna, Gabriele Escherich, Udo zur Stadt, Maurizio Aricò, Valentino Conter, Martin Schrappe, Maria Grazia Valsecchi, Andrea Biondi   +24 more
doaj   +1 more source

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

Haematologica, 2014
T-cell acute lymphoblastic leukemia arises from the leukemic transformation of developing thymocytes and results from cooperative genetic lesions. Inactivation of the PHF6 gene is frequently observed in T-cell acute lymphoblastic leukemia, suggesting an ...
Evelien Mets, Gert Van Peer, Joni Van der Meulen, Michael Boice, Tom Taghon, Steven Goossens, Pieter Mestdagh, Yves Benoit, Barbara De Moerloose, Nadine Van Roy, Bruce Poppe, Jo Vandesompele, Hans-Guido Wendel, Pieter Van Vlierberghe, Frank Speleman, Pieter Rondou   +15 more
doaj   +1 more source

Parents' Perception regarding their Children Suffering from Acute Lymphoblastic Leukemia at Nasser Institute Hospital [PDF]

Helwan International Journal for Nursing Research and Practice
Background: Acute lymphoblastic leukemia is a common cancer and life-threatening malignancy affects children health physically, psychologically and socially wellbeing over the world.
Fatma Mohamed
doaj   +1 more source

Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia with e1a3 BCR-ABL1 transcript in a Nigerian with sickle cell anemia: a case report

Journal of Medical Case Reports, 2021
Background The occurrence of acute leukemia in patients with sickle cell anemia is uncommon. The Philadelphia chromosome is the hallmark of chronic myeloid leukemia.
Ibrahim O. Ahmed, Lauretta O. Ochogwu, Temilola O. Owojuyigbe, Norah O. Akinola, Muheez A. Durosinmi   +4 more
doaj   +1 more source

Oral health management in children with acute lymphoblastic leukemia

口腔疾病防治, 2021
Acute lymphoblastic leukemia is the most common type of leukemia in children. In recent years, the treatment and prognosis of acute lymphoblastic leukemia in children have improved significantly. However, acute lymphoblastic leukemia itself and treatment
TANG Yawen, ZHANG Lin, YANG Xue, ZOU Jing, WANG Yan   +4 more
doaj   +1 more source