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Acute lymphoblastic leukemia [PDF]
Pediatric Blood & Cancer, 2021 AbstractThe survival of patients with acute lymphoblastic leukemia (ALL) has improved significantly with the use of intensive multimodality treatment regimens including chemotherapy, high‐dose chemotherapy and stem cell rescue, and radiation therapy when indicated.
John Han‐Chih Chang +4 more
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Pediatric acute lymphoblastic leukemia
Haematologica, 2020 The last decade has witnessed great advances in our understanding of the genetic and biological basis of childhood acute lymphoblastic leukemia (ALL), the development of experimental models to probe mechanisms and evaluate new therapies, and the development of more efficacious treatment stratification.
Charles G. Mullighan, Hiroto Inaba
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Acute Lymphoblastic Leukemia in Children [PDF]
New England Journal of Medicine, 2015 The most common cancer in childhood is now curable in 90% of patients. Current efforts are focused on devising molecular-based therapy for the subsets of acute lymphoblastic leukemia that are most resistant to current therapy.
Hunger, S.P., Mullighan, C.G.
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Quaternion-Valued Convolutional Neural Network Applied for Acute Lymphoblastic Leukemia Diagnosis [PDF]
A. Britto and K. Valdivia Delgado (Eds.): BRACIS 2021, LNAI 13074,
pp. 280-293, 2021. Springer Nature Switzerland AG 2021, 2021 The field of neural networks has seen significant advances in recent years with the development of deep and convolutional neural networks. Although many of the current works address real-valued models, recent studies reveal that neural networks with hypercomplex-valued parameters can better capture, generalize, and represent the complexity of ...
arxiv +1 more source
Acute Lymphoblastic Leukemia Detection Using Hypercomplex-Valued Convolutional Neural Networks [PDF]
2022 International Joint Conference on Neural Networks (IJCNN), 2022 This paper features convolutional neural networks defined on hypercomplex algebras applied to classify lymphocytes in blood smear digital microscopic images. Such classification is helpful for the diagnosis of acute lymphoblast leukemia (ALL), a type of blood cancer.
arxiv +1 more source
Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia. [PDF]
PLoS ONE, 2015 Osteonecrosis is one of the most common, serious, toxicities resulting from the treatment of acute lymphoblastic leukemia. In recent years, pediatric acute lymphoblastic leukemia clinical trials have used discontinuous rather than continuous dosing of ...
Laura B Ramsey +12 more
doaj +1 more source
Acute Lymphoblastic Leukemia, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
The Journal of the National Comprehensive Cancer Network, 2021 The NCCN Guidelines for Acute Lymphoblastic Leukemia (ALL) focus on the classification of ALL subtypes based on immunophenotype and cytogenetic/molecular markers; risk assessment and stratification for risk-adapted therapy; treatment strategies for ...
P. Brown +31 more
semanticscholar +1 more source
Advances in the Diagnosis and Treatment of Pediatric Acute Lymphoblastic Leukemia
Journal of Clinical Medicine, 2021 The outcomes of pediatric acute lymphoblastic leukemia (ALL) have improved remarkably during the last five decades. Such improvements were made possible by the incorporation of new diagnostic technologies, the effective administration of conventional ...
H. Inaba, C. Pui
semanticscholar +1 more source
Adult Acute Lymphoblastic Leukemia [PDF]
Mayo Clinic Proceedings, 2005 Much progress has been made in understanding the biology of and therapy for acute lymphoblastic leukemia (ALL). This progress has translated into the recognition of several subgroups of ALL and the institution of risk-adapted therapies. New therapies are emerging based on the definition of specific cytogenetic-molecular abnormalities.
Stefan Faderl +2 more
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Relapsed Acute Lymphoblastic Leukemia
Indian Journal of Pediatrics, 2023 AbstractOutcomes for children with acute lymphoblastic leukemia (ALL) have improved worldwide to >85%. For those who relapse, outcomes have remained static at ~50% making relapsed acute lymphoblastic leukemia one of the leading causes of death in childhood cancers.
Sidhu, Jasmeet +3 more
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