Results 1 to 10 of about 324,971 (204)

Acute lymphoblastic leukemia [PDF]

Pediatric Blood & Cancer, 2021
The survival of patients with acute lymphoblastic leukemia (ALL) has improved significantly with the use of intensive multimodality treatment regimens including chemotherapy, high‐dose chemotherapy and stem cell rescue, and radiation therapy when ...
John Han-Chih Chang, M. Poppe, Chia-Ho Hua, K. Marcus, N. Esiashvili   +4 more
semanticscholar   +6 more sources

Pediatric acute lymphoblastic leukemia

Haematologica, 2020
The last decade has witnessed great advances in our understanding of the genetic and biological basis of childhood acute lymphoblastic leukemia (ALL), the development of experimental models to probe mechanisms and evaluate new therapies, and the ...
H. Inaba, C. Mullighan
semanticscholar   +5 more sources

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

Cancer Cell, 2002
Rami Mahfouz, Mary V Relling, Dawn Wilkins   +2 more
exaly   +2 more sources

Acute Lymphoblastic Leukemia [PDF]

Journal of the National Comprehensive Cancer Network, 2012
The inaugural NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for acute lymphoblastic leukemia (ALL) were developed as a result of meetings convened by a multi-disciplinary panel of experts in 2011. These NCCN Guidelines provide recommendations on the diagnostic evaluation and workup for ALL, risk assessment, risk-stratified treatment ...
Joseph C, Alvarnas, Patrick A, Brown, Patricia, Aoun, Karen Kuhn, Ballen, Naresh, Bellam, William, Blum, Michael W, Boyer, Hetty E, Carraway, Peter F, Coccia, Steven E, Coutre, Jennifer, Cultrera, Lloyd E, Damon, Daniel J, DeAngelo, Dan, Douer, Haydar, Frangoul, Olga, Frankfurt, Salil, Goorha, Michael M, Millenson, Susan, O'Brien, Stephen H, Petersdorf, Arati V, Rao, Stephanie, Terezakis, Geoffrey, Uy, Meir, Wetzler, Andrew D, Zelenetz, Maoko, Naganuma, Kristina M, Gregory   +26 more
openaire   +4 more sources

Asciminib for relapsed or refractory Philadelphia chromosome–positive acute lymphoblastic leukemia [PDF]

Blood Advances
Mathilde Chanut, Aurélie Cabannes-Hamy, Marie Balsat, Nassim Sahki, Emmanuel Raffoux, Yosr Hicheri, Bruno Lioure, Lucie Laemmel, Thibaut Leguay, Victoria Cacheux, Maria Pilar Gallego-Hernanz, Andrea Pieragostini, Gabrielle Roth-Guepin, Ludovic Gabellier, Nathalie Denizon, Lise Willems, Quentin Cabrera, Sylvain Chantepie, Valérie Coiteux, Claudie Capdupuy, Martin Carré, Antoine Machet, Juliette Lambert, Sandrine Roux, Franck-Emmanuel Nicolini, Nicolas Boissel, Emmanuelle Clappier, Rathana Kim, Philippe Rousselot   +28 more
doaj   +2 more sources

A case of therapy-related acute lymphoblastic leukemia following the treatment of acute myeloid leukemia

Leukemia Research Reports, 2022
Therapy-related acute lymphoblastic leukemia represents a distinct entity associated with inferior survival compared with de novo acute lymphoblastic leukemia.
Sufana Shikdar, Yuan Ying, Mohamad Khawandanah   +2 more
doaj   +1 more source

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia. [PDF]

PLoS ONE, 2015
Osteonecrosis is one of the most common, serious, toxicities resulting from the treatment of acute lymphoblastic leukemia. In recent years, pediatric acute lymphoblastic leukemia clinical trials have used discontinuous rather than continuous dosing of ...
Laura B Ramsey, Laura J Janke, Monique A Payton, Xiangjun Cai, Steven W Paugh, Seth E Karol, Landry Kamdem Kamdem, Cheng Cheng, Richard T Williams, Sima Jeha, Ching-Hon Pui, William E Evans, Mary V Relling   +12 more
doaj   +1 more source

Relapsed Acute Lymphoblastic Leukemia

Indian Journal of Pediatrics, 2023
AbstractOutcomes for children with acute lymphoblastic leukemia (ALL) have improved worldwide to >85%. For those who relapse, outcomes have remained static at ~50% making relapsed acute lymphoblastic leukemia one of the leading causes of death in childhood cancers.
Sidhu, Jasmeet, Gogoi, Manash Pratim, Krishnan, Shekhar, Saha, Vaskar   +3 more
openaire   +3 more sources

Adult Acute Lymphoblastic Leukemia [PDF]

Mayo Clinic Proceedings, 2005
Much progress has been made in understanding the biology of and therapy for acute lymphoblastic leukemia (ALL). This progress has translated into the recognition of several subgroups of ALL and the institution of risk-adapted therapies. New therapies are emerging based on the definition of specific cytogenetic-molecular abnormalities.
Shilpa, Paul, Hagop, Kantarjian, Elias J, Jabbour   +2 more
openaire   +3 more sources

Tisagenlecleucel in Children and Young Adults with B‐Cell Lymphoblastic Leukemia

New England Journal of Medicine, 2018
Background In a single‐center phase 1–2a study, the anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy tisagenlecleucel produced high rates of complete remission and was associated with serious but mainly reversible toxic effects in children and ...
S. Maude, T. Laetsch, J. Buechner, S. Rives, M. Boyer, H. Bittencourt, P. Bader, M. Verneris, H. Stefanski, G. D. Myers, M. Qayed, B. De Moerloose, H. Hiramatsu, Krysta D Schlis, K. Davis, P. Martin, Eneida R. Nemecek, G. Yanik, C. Peters, A. Baruchel, N. Boissel, F. Mechinaud, A. Balduzzi, J. Krueger, C. June, B. Levine, P. Wood, T. Taran, M. Leung, K. Mueller, Yiyun Zhang, K. Sen, D. Lebwohl, M. Pulsipher, S. Grupp   +34 more
semanticscholar   +1 more source