Results 11 to 20 of about 124,423 (315)

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]

open access: yes, 2012
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
zur Stadt, Udo   +51 more
core   +1 more source

Parents' Perception regarding their Children Suffering from Acute Lymphoblastic Leukemia at Nasser Institute Hospital [PDF]

open access: yesHelwan International Journal for Nursing Research and Practice
Background: Acute lymphoblastic leukemia is a common cancer and life-threatening malignancy affects children health physically, psychologically and socially wellbeing over the world.
Fatma Mohamed
doaj   +1 more source

Oral health management in children with acute lymphoblastic leukemia

open access: yes口腔疾病防治, 2021
Acute lymphoblastic leukemia is the most common type of leukemia in children. In recent years, the treatment and prognosis of acute lymphoblastic leukemia in children have improved significantly. However, acute lymphoblastic leukemia itself and treatment
TANG Yawen   +4 more
doaj   +1 more source

Therapy-related acute lymphoblastic leukemia has distinct clinical and cytogenetic features compared to de novo acute lymphoblastic leukemia, but outcomes are comparable in transplanted patients

open access: yesHaematologica, 2018
Therapy-related acute lymphoblastic leukemia remains poorly defined due to a lack of large data sets recognizing the defining characteristics of this entity.
Ibrahim Aldoss   +20 more
doaj   +1 more source

Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia with e1a3 BCR-ABL1 transcript in a Nigerian with sickle cell anemia: a case report

open access: yesJournal of Medical Case Reports, 2021
Background The occurrence of acute leukemia in patients with sickle cell anemia is uncommon. The Philadelphia chromosome is the hallmark of chronic myeloid leukemia.
Ibrahim O. Ahmed   +4 more
doaj   +1 more source

Evaluation of Plasma Level of Anticoagulant Proteins (Protein C, S and Anti thrombin III) in Patients with Acute Lymphoblastic Leukemia [PDF]

open access: yesAl-Azhar International Medical Journal, 2023
Background: Acute lymphoblastic leukemia (ALL) is related to many coagulation abnormalities like hemorrhage and thrombosis.Objectives: research was to assess role of plasma activity levels of anticoagulant proteins( Protein C, Protein S & Anti ...
ibrahim Hazman   +3 more
doaj   +1 more source

Association of ARID5B gene variants with acute lymphoblastic leukemia in Yemeni children

open access: yesTumor Biology, 2017
Studies have shown an association between ARID5B gene polymorphisms and childhood acute lymphoblastic leukemia. However, the association between ARID5B variants and acute lymphoblastic leukemia among the Arab population still needs to be studied. The aim
Boshra Al-absi   +6 more
doaj   +1 more source

In vitro validation of γ-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia

open access: yesHaematologica, 2008
Background Activating NOTCH1 mutations are common in T-cell acute lymphoblastic leukemia. Inhibition of NOTCH1 signaling with γ-secretase inhibitors causes cell cycle block, but only after treatment for several days.
Kim De Keersmaecker   +9 more
doaj   +1 more source

Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia

open access: yesHaematologica, 2010
Background Differences in survival have been reported between pediatric and adult acute lymphoblastic leukemia. The inferior prognosis in adult acute lymphoblastic leukemia is not fully understood but could be attributed, in part, to differences in ...
Ryoko Okamoto   +12 more
doaj   +1 more source

Hospital acquired pneumonia risk factors in children with Acute Lymphoblastic Leukemia on chemotherapy

open access: yesHeliyon, 2021
Background: Over the past 10 years, infection has remained as the main cause of illness and mortality among children with Acute Lymphoblastic Leukemia on chemotherapy. The high incidence of Hospital-Acquired Pneumonia in children with Acute Lymphoblastic
Anitha Marllyin Mairuhu   +7 more
doaj   +1 more source

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